2017
Adverse Remodeling and Reverse Remodeling After Myocardial Infarction
Bhatt AS, Ambrosy AP, Velazquez EJ. Adverse Remodeling and Reverse Remodeling After Myocardial Infarction. Current Cardiology Reports 2017, 19: 71. PMID: 28660552, DOI: 10.1007/s11886-017-0876-4.Peer-Reviewed Original ResearchMeSH KeywordsHeart FailureHeart VentriclesHumansMyocardial InfarctionStroke VolumeVentricular RemodelingConceptsAdverse LV remodelingMyocardial infarctionLV remodelingAdverse remodelingNeurohormonal regulationLeft ventricleCurrent evidence-based therapiesPost-MI heart failurePoor clinical outcomeAdverse cardiac remodelingPost-MI settingDevice-based therapiesEvidence-based therapiesNeurohormonal blockadeEarly revascularizationPathophysiological considerationsHeart failureVentricular dyssynchronyClinical outcomesEjection fractionMultiple imaging modalitiesCardiac remodelingTreatment strategiesReviewThe purposeInfarction
2016
Reassessment of Cardiac Function and Implantable Cardioverter-Defibrillator Use Among Medicare Patients With Low Ejection Fraction After Myocardial Infarction
Pokorney SD, Miller AL, Chen AY, Thomas L, Fonarow GC, de Lemos JA, Al-Khatib SM, Velazquez EJ, Peterson ED, Wang TY. Reassessment of Cardiac Function and Implantable Cardioverter-Defibrillator Use Among Medicare Patients With Low Ejection Fraction After Myocardial Infarction. Circulation 2016, 135: 38-47. PMID: 27881561, DOI: 10.1161/circulationaha.116.022359.Peer-Reviewed Original ResearchMeSH KeywordsAgedDatabases, FactualDefibrillators, ImplantableFemaleHeart VentriclesHumansMagnetic Resonance ImagingMaleMedicareMyocardial InfarctionMyocardial RevascularizationProportional Hazards ModelsRegistriesRetrospective StudiesStroke VolumeSurvival RateTomography, X-Ray ComputedUltrasonographyUnited StatesConceptsLow ejection fractionEjection fractionICD implantationMyocardial infarctionMI admissionsRevascularization statusImplantable cardioverter-defibrillator (ICD) useACTION Registry-GWTGICD implantation ratesMultivariable Cox modelPost-MI patientsYears of ageImplantation rateCardiac functionMedicare patientsCox modelPatientsAdmissionHigher likelihoodInfarctionImplantationAssociationYearsStatusICDPredicting Outcomes Over Time in Patients With Heart Failure, Left Ventricular Systolic Dysfunction, or Both Following Acute Myocardial Infarction
Lopes RD, Pieper KS, Stevens SR, Solomon SD, McMurray JJ, Pfeffer MA, Leimberger JD, Velazquez EJ. Predicting Outcomes Over Time in Patients With Heart Failure, Left Ventricular Systolic Dysfunction, or Both Following Acute Myocardial Infarction. Journal Of The American Heart Association 2016, 5: e003045. PMID: 27353607, PMCID: PMC4937254, DOI: 10.1161/jaha.115.003045.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedEpidemiologic MethodsFemaleHeart FailureHospitalizationHumansMaleMiddle AgedMyocardial InfarctionPrognosisVentricular Dysfunction, LeftConceptsVentricular systolic dysfunctionHeart failureMyocardial infarctionIntegrated discrimination improvementSystolic dysfunctionCardiovascular deathMultivariable Cox proportional hazardsAcute Myocardial Infarction trialNet reclassification improvement indexNonfatal heart failureMyocardial Infarction trialNonfatal myocardial infarctionPredictors of mortalityPatient informationBaseline heart rateAcute myocardial infarctionCox proportional hazardsCreatinine clearanceHospital arrivalHospital dischargeIndex hospitalizationPatient characteristicsOverall mortalityIndex eventClinical eventsCardiovascular Outcomes According to Systolic Blood Pressure in Patients With and Without Diabetes: An ACCOMPLISH Substudy
Weber MA, Bloch M, Bakris GL, Weir MR, Zappe DH, Dahlof B, Velazquez EJ, Pitt B, Basile JN, Jamerson K, Hua TA. Cardiovascular Outcomes According to Systolic Blood Pressure in Patients With and Without Diabetes: An ACCOMPLISH Substudy. Journal Of Clinical Hypertension 2016, 18: 299-307. PMID: 27060568, PMCID: PMC8032014, DOI: 10.1111/jch.12816.Peer-Reviewed Original ResearchMeSH KeywordsAgedAntihypertensive AgentsBlood PressureBlood Pressure DeterminationDiabetes Mellitus, Type 2Double-Blind MethodDrug Therapy, CombinationFemaleFollow-Up StudiesHumansHypertensionIncidenceMaleMyocardial InfarctionProspective StudiesRisk AssessmentRisk FactorsStrokeSurvival RateSystoleTreatment OutcomeUnited StatesConceptsSystolic blood pressureNondiabetic cohortCardiovascular outcomesPrimary endpointBlood pressurePrimary endpoint event rateTreatment systolic blood pressureEvent ratesAvoiding Cardiovascular EventsBlood pressure targetsDifferent SBP targetsFurther SBP reductionSystolic Hypertension (ACCOMPLISH) trialAdverse renal eventsComposite primary endpointTotal stroke ratesCV protectionNondiabetic patientsRenal considerationsRenal eventsSBP categoriesSBP reductionCardiovascular eventsHypertension trialsPressure targets
2015
Clinical predictors and outcomes of patients with left ventricular thrombus following ST-segment elevation myocardial infarction
Garber AM, Mentz RJ, Al-Khalidi HR, Shaw LK, Fiuzat M, O’Connor C, Velazquez EJ. Clinical predictors and outcomes of patients with left ventricular thrombus following ST-segment elevation myocardial infarction. Journal Of Thrombosis And Thrombolysis 2015, 41: 365-373. PMID: 26202909, DOI: 10.1007/s11239-015-1252-0.Peer-Reviewed Original ResearchMeSH KeywordsAgedFemaleHeart VentriclesHumansMaleMiddle AgedModels, BiologicalMyocardial InfarctionPredictive Value of TestsThrombosisConceptsST-segment elevation myocardial infarctionElevation myocardial infarctionNon-white raceHF severityBaseline characteristicsClinical predictorsHeart failureIndependent predictorsMyocardial infarctionHeart rateCox proportional hazards regression modelProportional hazards regression modelsLeft ventricular thrombusLong-term mortalityOutcomes of patientsVentricular thrombus formationHazards regression modelsHigher heart rateEligible patientsInitial troponinCause mortalityLAD diseaseSTEMI patientsVentricular thrombusTransthoracic echocardiogramOutcomes of Anatomical versus Functional Testing for Coronary Artery Disease
Douglas PS, Hoffmann U, Patel MR, Mark DB, Al-Khalidi HR, Cavanaugh B, Cole J, Dolor RJ, Fordyce CB, Huang M, Khan MA, Kosinski AS, Krucoff MW, Malhotra V, Picard MH, Udelson JE, Velazquez EJ, Yow E, Cooper LS, Lee KL. Outcomes of Anatomical versus Functional Testing for Coronary Artery Disease. New England Journal Of Medicine 2015, 372: 1291-1300. PMID: 25773919, PMCID: PMC4473773, DOI: 10.1056/nejmoa1415516.Peer-Reviewed Original ResearchConceptsObstructive coronary artery diseaseCoronary artery diseaseCTA groupSymptomatic patientsArtery diseaseComposite primary end pointPrimary end-point eventEnd pointRadiation exposureInvasive cardiac catheterizationMajor procedural complicationsPrimary end pointSecondary end pointsEnd-point eventsCumulative radiation exposureMedian followChest painUnstable anginaCardiac catheterizationMore patientsProcedural complicationsClinical outcomesRandomized trialsAnatomical testingMean ageSex differences in clinical characteristics and outcomes after myocardial infarction: insights from the Valsartan in Acute Myocardial Infarction Trial (VALIANT)
Lam CS, McEntegart M, Claggett B, Liu J, Skali H, Lewis E, Køber L, Rouleau J, Velazquez E, Califf R, McMurray JJ, Pfeffer M, Solomon S. Sex differences in clinical characteristics and outcomes after myocardial infarction: insights from the Valsartan in Acute Myocardial Infarction Trial (VALIANT). European Journal Of Heart Failure 2015, 17: 301-312. PMID: 25655011, DOI: 10.1002/ejhf.238.Peer-Reviewed Original ResearchConceptsAcute Myocardial Infarction trialMyocardial Infarction trialVentricular systolic dysfunctionHeart failureMyocardial infarctionSystolic dysfunctionClinical characteristicsVentricular volumeKillip class III/IVLeft ventricular systolic dysfunctionRisk of HFClass III/IVHigher long-term riskSmaller left ventricular volumesSimilar ejection fractionLong-term mortalityPost-infarction anginaRisk of hospitalizationSubset of patientsNon-fatal outcomesLong-term riskLeft ventricular volumeAssociation of sexMore comorbiditiesCardiovascular death
2014
Impact of Cardiovascular Events on Change in Quality of Life and Utilities in Patients After Myocardial Infarction A VALIANT Study (Valsartan In Acute Myocardial Infarction)
Lewis EF, Li Y, Pfeffer MA, Solomon SD, Weinfurt KP, Velazquez EJ, Califf RM, Rouleau JL, Kober L, White HD, Schulman KA, Reed SD. Impact of Cardiovascular Events on Change in Quality of Life and Utilities in Patients After Myocardial Infarction A VALIANT Study (Valsartan In Acute Myocardial Infarction). JACC Heart Failure 2014, 2: 159-165. PMID: 24720924, DOI: 10.1016/j.jchf.2013.12.003.Peer-Reviewed Original ResearchMeSH KeywordsAcute DiseaseAgedAngiotensin II Type 1 Receptor BlockersAngiotensin-Converting Enzyme InhibitorsBundle-Branch BlockCaptoprilDeath, Sudden, CardiacDrug Therapy, CombinationFemaleHealth StatusHeart FailureHospitalizationHumansMaleMyocardial InfarctionQuality of LifeRecurrenceStrokeSurvivorsTetrazolesTreatment OutcomeValineValsartanConceptsNonfatal CV eventsEQ-5D assessmentCV eventsVisual analog scaleEQ-5D scoresCardiovascular eventsMyocardial infarctionEQ-5DBaseline EQ-5D scoresKillip class IINonfatal cardiovascular eventsHealth-related qualityLinear mixed-effects regression modelsQuality of lifeMixed effects regression modelsVALIANT studyWorse HRQLVAS scoresEjection fractionNonfatal eventsMI survivorsAnalog scaleVALIANT trialGeneric instrumentsPatients
2013
Early Echocardiographic Deformation Analysis for the Prediction of Sudden Cardiac Death and Life-Threatening Arrhythmias After Myocardial Infarction
Ersbøll M, Valeur N, Andersen MJ, Mogensen UM, Vinther M, Svendsen JH, Møller JE, Kisslo J, Velazquez EJ, Hassager C, Søgaard P, Køber L. Early Echocardiographic Deformation Analysis for the Prediction of Sudden Cardiac Death and Life-Threatening Arrhythmias After Myocardial Infarction. JACC Cardiovascular Imaging 2013, 6: 851-860. PMID: 23850252, DOI: 10.1016/j.jcmg.2013.05.009.Peer-Reviewed Original ResearchMeSH KeywordsAgedArrhythmias, CardiacDeath, Sudden, CardiacDefibrillators, ImplantableDenmarkEchocardiographyElectric CountershockFemaleHumansMaleMiddle AgedMultivariate AnalysisMyocardial InfarctionPredictive Value of TestsPrimary PreventionProportional Hazards ModelsProspective StudiesRisk FactorsStroke VolumeTreatment OutcomeVentricular Function, LeftConceptsGlobal longitudinal strainAcute myocardial infarctionSudden cardiac deathMalignant ventricular arrhythmiasMyocardial infarctionNet reclassification indexVentricular arrhythmiasCardiac deathAddition of GLSMeasurement of GLSSCD/VAsChronic ischemic heart failureNovel echocardiographic parametersPrimary composite endpointPrimary composite outcomeIschemic heart failureEchocardiographic parametersPrimary endpointComposite outcomeHospital dischargeLate complicationsMultivariate adjustmentComposite endpointHeart failureRisk stratificationPrediction of All-Cause Mortality and Heart Failure Admissions From Global Left Ventricular Longitudinal Strain in Patients With Acute Myocardial Infarction and Preserved Left Ventricular Ejection Fraction
Ersbøll M, Valeur N, Mogensen UM, Andersen MJ, Møller JE, Velazquez EJ, Hassager C, Søgaard P, Køber L. Prediction of All-Cause Mortality and Heart Failure Admissions From Global Left Ventricular Longitudinal Strain in Patients With Acute Myocardial Infarction and Preserved Left Ventricular Ejection Fraction. Journal Of The American College Of Cardiology 2013, 61: 2365-2373. PMID: 23563128, DOI: 10.1016/j.jacc.2013.02.061.Peer-Reviewed Original ResearchMeSH KeywordsAgedCause of DeathCohort StudiesConfidence IntervalsEchocardiography, DopplerFemaleHeart FailureHumansMaleMiddle AgedMultivariate AnalysisMyocardial InfarctionPredictive Value of TestsPrognosisProportional Hazards ModelsProspective StudiesRisk AssessmentSeverity of Illness IndexStroke VolumeSurvival RateVentricular Dysfunction, LeftConceptsGlobal longitudinal strainHeart failure hospitalizationVentricular ejection fractionAcute myocardial infarctionMyocardial infarctionFailure hospitalizationSecondary endpointsEjection fractionHigh-risk myocardial infarctionVentricular global longitudinal strainLeft ventricular ejection fractionLongitudinal strainHeart failure admissionsPrimary composite endpointCox regression analysisHigh-risk subjectsVentricular longitudinal strainImportant prognostic informationSignificant prognostic valueAssessment of GLSParticular clinical relevanceCardiovascular deathCause mortalityPrimary endpointCardiac death
2012
A Quality Improvement Framework for Equity in Cardiovascular Care: Results of a National Collaborative
Siegel B, Sears V, Bretsch JK, Wilson M, Jones KC, Mead H, Hasnain-Wynia R, Ayala RK, Bhalla R, Cornue CM, Emrich CM, Patel P, Setzer JR, Suitonu J, Velazquez EJ, Eagle KA, Winniford MD. A Quality Improvement Framework for Equity in Cardiovascular Care: Results of a National Collaborative. Journal For Healthcare Quality 2012, 34: 32-43. PMID: 23552200, DOI: 10.1111/j.1945-1474.2011.00196.x.Peer-Reviewed Original ResearchConceptsPatient demographic dataCardiovascular careDemographic dataHeart Failure QualityPatient demographic characteristicsMinority patient populationAcute myocardial infarctionCare of minoritiesEvidence-based practice toolsStandardized collectionEvidence-based measuresComposite measureHispanic patientsAbility of hospitalsMyocardial infarctionPatient populationPatient raceQuality improvement toolsCardiac careMAIN OUTCOMEQuality improvement frameworkCardiac volumesQuality improvement methodsHospitalEthnic disparitiesMechanisms and Predictors of Mitral Regurgitation after High-Risk Myocardial Infarction
Meris A, Amigoni M, Verma A, Thune JJ, Køber L, Velazquez E, McMurray JJ, Pfeffer MA, Califf R, Levine RA, Solomon SD, Investigators V. Mechanisms and Predictors of Mitral Regurgitation after High-Risk Myocardial Infarction. Journal Of The American Society Of Echocardiography 2012, 25: 535-542. PMID: 22305962, PMCID: PMC3501447, DOI: 10.1016/j.echo.2012.01.006.Peer-Reviewed Original ResearchMeSH KeywordsAdultAge FactorsAgedAngiotensin-Converting Enzyme InhibitorsCaptoprilDisease ProgressionEchocardiography, Doppler, ColorElectrocardiographyFemaleFollow-Up StudiesHumansMaleMiddle AgedMitral Valve InsufficiencyMonitoring, PhysiologicMultivariate AnalysisMyocardial InfarctionPredictive Value of TestsProspective StudiesReference ValuesReproducibility of ResultsRisk AssessmentROC CurveSeverity of Illness IndexSex FactorsStatistics, NonparametricStroke VolumeTetrazolesTime FactorsValineValsartanVentricular Dysfunction, LeftVentricular RemodelingConceptsHigh-risk myocardial infarctionBaseline mitral regurgitationMitral regurgitationMyocardial infarctionAtrial sizeIndependent predictorsCoaptation depthProgression of MRMitral valve deformationStructural valve diseaseSevere mitral regurgitationFunctional mitral regurgitationIschemic mitral regurgitationGood-quality echocardiogramsMitral annular areaMitral tentingMR degreeLV dysfunctionTenting areaBaseline characteristicsDiastolic functionHeart failureValve diseaseLV remodelingVentricular remodeling
2011
Responses of mental stress–induced myocardial ischemia to escitalopram treatment: Background, design, and method for the Responses of Mental Stress Induced Myocardial Ischemia to Escitalopram Treatment trial
Jiang W, Velazquez EJ, Samad Z, Kuchibhatla M, Martsberger C, Rogers J, Williams R, Kuhn C, Ortel TL, Becker RC, Pristera N, Krishnan R, O'Connor CM. Responses of mental stress–induced myocardial ischemia to escitalopram treatment: Background, design, and method for the Responses of Mental Stress Induced Myocardial Ischemia to Escitalopram Treatment trial. American Heart Journal 2011, 163: 20-26. PMID: 22172432, PMCID: PMC3254211, DOI: 10.1016/j.ahj.2011.09.018.Peer-Reviewed Original ResearchConceptsMental stress-induced myocardial ischemiaCoronary heart diseaseStable coronary heart diseaseStress-induced myocardial ischemiaMyocardial ischemiaMental Stress–Induced Myocardial IschemiaSelective serotonin reuptake inhibitor (SSRI) treatmentStress testingSerotonin reuptake inhibitor treatmentEjection fraction reductionReuptake inhibitor treatmentMental stress testingPsychometric questionnairesEffects of SSRIsIschemic ST changesInduced Myocardial IschemiaAbnormal wall motionAdult patientsEscitalopram treatmentSSRI treatmentPoor outcomeTreatment trialsPlatelet activityHeart diseaseRisk factorsCardiac structure and function, remodeling, and clinical outcomes among patients with diabetes after myocardial infarction complicated by left ventricular systolic dysfunction, heart failure, or both
Shah AM, Hung CL, Shin SH, Skali H, Verma A, Ghali JK, Køber L, Velazquez EJ, Rouleau JL, McMurray JJ, Pfeffer MA, Solomon SD. Cardiac structure and function, remodeling, and clinical outcomes among patients with diabetes after myocardial infarction complicated by left ventricular systolic dysfunction, heart failure, or both. American Heart Journal 2011, 162: 685-691. PMID: 21982661, DOI: 10.1016/j.ahj.2011.07.015.Peer-Reviewed Original ResearchMeSH KeywordsAgedDiabetes ComplicationsFemaleHeart FailureHumansMaleMiddle AgedMyocardial InfarctionUltrasonographyVentricular Dysfunction, LeftVentricular RemodelingConceptsLV mass indexRisk of deathRelative wall thicknessDiabetic patientsEjection fractionMass indexHigh riskBaseline LV mass indexLeft ventricular systolic dysfunctionHigher LV mass indexHeart failure post-myocardial infarctionVALIANT Echo studyAtrial volume indexVentricular systolic dysfunctionAge-adjusted modelsQuantitative echocardiographic analysisPost-myocardial infarctionHF hospitalizationLong-term elevationNondiabetic patientsConcentric remodelingSystolic dysfunctionAtrial enlargementHeart failureClinical outcomesCircumstances and Outcomes of Sudden Unexpected Death in Patients With High-Risk Myocardial Infarction
Ye S, Grunnert M, Thune JJ, Stephenson KM, Uno H, Finn PV, McMurray JJ, Velazquez EJ, Califf R, Pfeffer MA, Solomon SD. Circumstances and Outcomes of Sudden Unexpected Death in Patients With High-Risk Myocardial Infarction. Circulation 2011, 123: 2674-2680. PMID: 21606398, DOI: 10.1161/circulationaha.110.990655.Peer-Reviewed Original ResearchConceptsHigh-risk myocardial infarctionSudden deathMyocardial infarctionHospital eventsVentricular tachycardia/ventricular fibrillationPrevention of SDSD eventsLong-term mortalityMajority of patientsSudden unexpected deathInitial ECG rhythmCatastrophic complicationUnwitnessed arrestsUnexpected deathVentricular fibrillationTrial trialsPatientsInfarctionECG rhythmDeathPreventionHigher proportionHome eventsArrestSource documentationIncremental value of echocardiographic assessment beyond clinical evaluation for prediction of death and development of heart failure after high-risk myocardial infarction
Verma A, Pfeffer MA, Skali H, Rouleau J, Maggioni A, McMurray JJ, Califf RM, Velazquez EJ, Solomon SD. Incremental value of echocardiographic assessment beyond clinical evaluation for prediction of death and development of heart failure after high-risk myocardial infarction. American Heart Journal 2011, 161: 1156-1162. PMID: 21641363, DOI: 10.1016/j.ahj.2011.03.024.Peer-Reviewed Original ResearchConceptsLV ejection fractionHigh-risk myocardial infarctionOutcome of deathHeart failureEchocardiographic measuresMyocardial infarctionEchocardiographic assessmentEjection fractionPrognostic valueClinical variablesClinical assessmentPredictive valueRight ventricular fractional area changeMultivariable proportional hazards modelsVentricular fractional area changeLeft ventricular ejection fractionMinimal prognostic valueAtrial volume indexIncremental prognostic valuePredictors of deathVentricular mass indexVentricular ejection fractionLeft ventricular functionPrediction of deathImportant prognostic informationPredictors and prognostic impact of recurrent myocardial infarction in patients with left ventricular dysfunction, heart failure, or both following a first myocardial infarction
Thune JJ, Signorovitch JE, Kober L, McMurray JJ, Swedberg K, Rouleau J, Maggioni A, Velazquez E, Califf R, Pfeffer MA, Solomon SD. Predictors and prognostic impact of recurrent myocardial infarction in patients with left ventricular dysfunction, heart failure, or both following a first myocardial infarction. European Journal Of Heart Failure 2011, 13: 148-153. PMID: 21037250, DOI: 10.1093/eurjhf/hfq194.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsAgedCaptoprilCause of DeathConfidence IntervalsDrug Therapy, CombinationFemaleFollow-Up StudiesHeart FailureHumansMaleMiddle AgedMultivariate AnalysisMyocardial InfarctionPredictive Value of TestsPrognosisProportional Hazards ModelsRecurrenceRisk AssessmentSeverity of Illness IndexSex FactorsSurvival AnalysisTetrazolesTime FactorsValineValsartanVentricular Dysfunction, LeftConceptsRecurrent myocardial infarctionFirst myocardial infarctionRisk of deathLeft ventricular dysfunctionMyocardial infarctionVentricular dysfunctionHeart failurePrognostic impactOne-year mortalityGlomerular filtration rateEarly reinfarctionLate reinfarctionTrial cohortUnstable anginaProlong survivalMedian timeMI survivorsFiltration ratePatientsContemporary managementContemporary treatmentInfarctionMortalityReinfarctionDeath
2010
The inter‐relationship of diabetes and left ventricular systolic function on outcome after high‐risk myocardial infarction
Shah AM, Uno H, Køber L, Velazquez EJ, Maggioni AP, MacDonald MR, Petrie MC, McMurray JJ, Califf RM, Pfeffer MA, Solomon SD. The inter‐relationship of diabetes and left ventricular systolic function on outcome after high‐risk myocardial infarction. European Journal Of Heart Failure 2010, 12: 1229-1237. PMID: 20965879, DOI: 10.1093/eurjhf/hfq179.Peer-Reviewed Original ResearchConceptsLeft ventricular ejection fractionRecurrent myocardial infarctionHF hospitalizationRisk of deathMyocardial infarctionCause mortalityHigh riskSpectrum of LVEFHigh-risk post-MI patientsBaseline left ventricular ejection fractionHigher left ventricular ejection fractionHigh-risk myocardial infarctionAcute Myocardial Infarction trialCox proportional hazards modelPost-MI populationHeart failure hospitalizationMyocardial Infarction trialNon-diabetic patientsVentricular systolic functionVentricular ejection fractionPost-MI patientsAcute myocardial infarctionPotent risk factorProportional hazards modelFailure hospitalizationLongitudinal and Circumferential Strain Rate, Left Ventricular Remodeling, and Prognosis After Myocardial Infarction
Hung CL, Verma A, Uno H, Shin SH, Bourgoun M, Hassanein AH, McMurray JJ, Velazquez EJ, Kober L, Pfeffer MA, Solomon SD, Investigators V. Longitudinal and Circumferential Strain Rate, Left Ventricular Remodeling, and Prognosis After Myocardial Infarction. Journal Of The American College Of Cardiology 2010, 56: 1812-1822. PMID: 21087709, DOI: 10.1016/j.jacc.2010.06.044.Peer-Reviewed Original ResearchMeSH KeywordsAgedBiomechanical PhenomenaFemaleHumansMaleMiddle AgedMyocardial InfarctionPrognosisUltrasonographyVentricular RemodelingConceptsCircumferential SRMyocardial infarctionHeart failureLongitudinal SRHigh-risk myocardial infarctionVALIANT Echo studyLong-term outcomesMultivariable logistic regressionStandard echocardiographic measuresClinical prognostic valueVentricular contractile performanceCox proportional hazardsParasternal short-axis viewCircumferential strain rateSpeckle-tracking softwareShort-axis viewHospital stayLV dysfunctionSystolic functionEchocardiographic measuresIndependent predictorsClinical outcomesVentricular enlargementPrognostic valueSystolic SRThe STICH trial: evidence‐based conclusions
Rouleau JL, Michler RE, Velazquez EJ, Oh JK, O'Connor CM, Desvigne‐Nickens P, Sopko G, Lee KL, Jones RH. The STICH trial: evidence‐based conclusions. European Journal Of Heart Failure 2010, 12: 1028-1030. PMID: 20861132, DOI: 10.1093/eurjhf/hfq140.Peer-Reviewed Original Research