Prognostic Significance of Biomarkers in Predicting Outcome in Patients With Coronary Artery Disease and Left Ventricular Dysfunction
Feldman AM, Mann DL, She L, Bristow MR, Maisel AS, McNamara DM, Walsh R, Lee DL, Wos S, Lang I, Wells G, Drazner MH, Schmedtje JF, Pauly DF, Sueta CA, Di Maio M, Kron IL, Velazquez EJ, Lee KL. Prognostic Significance of Biomarkers in Predicting Outcome in Patients With Coronary Artery Disease and Left Ventricular Dysfunction. Circulation Heart Failure 2013, 6: 461-472. PMID: 23584092, PMCID: PMC3905743, DOI: 10.1161/circheartfailure.112.000185.Peer-Reviewed Original ResearchConceptsCoronary artery bypassPrimary end pointCoronary artery diseaseIndependent prognostic informationArtery bypassMultivariable analysisPrognostic informationSTNFR-1Artery diseaseClinical factorsPlasma levelsUnivariate analysisIschemic Heart Failure (STICH) trialEnd pointSoluble tumor necrosisHeart Failure TrialLeft ventricular reconstructionPrimary outcome variableNet reclassification improvementAbility of biomarkersSubstudy patientsVentricular dysfunctionCardiac hospitalizationBiomarker substudyHeart failure