2017
Comparison of Incidence of Left Ventricular Systolic Dysfunction Among Patients With Left Bundle Branch Block Versus Those With Normal QRS Duration
Sze E, Dunning A, Loring Z, Atwater BD, Chiswell K, Daubert JP, Kisslo JA, Mark DB, Velazquez EJ, Samad Z. Comparison of Incidence of Left Ventricular Systolic Dysfunction Among Patients With Left Bundle Branch Block Versus Those With Normal QRS Duration. The American Journal Of Cardiology 2017, 120: 1990-1997. PMID: 28958452, DOI: 10.1016/j.amjcard.2017.08.003.Peer-Reviewed Original ResearchConceptsLeft ventricular systolic dysfunctionLeft bundle branch blockVentricular systolic dysfunctionBundle branch blockEjection fractionBaseline echocardiogramSystolic dysfunctionBranch blockQRS durationRisk factorsRelative riskLeft ventricular assist deviceNarrow QRS durationCohort of patientsNormal QRS durationFinal study cohortCommon risk factorsComparison of incidenceVentricular assist deviceHeart transplantStudy cohortLBBB patientsHigh incidencePatientsEchocardiogram
2015
The MitraClip and survival in patients with mitral regurgitation at high risk for surgery: A propensity-matched comparison
Velazquez EJ, Samad Z, Al-Khalidi HR, Sangli C, Grayburn PA, Massaro JM, Stevens SR, Feldman TE, Krucoff MW. The MitraClip and survival in patients with mitral regurgitation at high risk for surgery: A propensity-matched comparison. American Heart Journal 2015, 170: 1050-1059.e3. PMID: 26542516, DOI: 10.1016/j.ahj.2015.08.004.Peer-Reviewed Original ResearchConceptsMitraClip patientsCox proportional hazards modelPropensity-matched comparisonSevere MR patientsHigh surgical riskHigh-risk patientsNon-surgical treatmentKaplan-Meier estimatesMitral regurgitation patientsProportional hazards modelSurvival benefitMedical therapySurgical riskMitral regurgitationRelative riskBaseline differencesHigh riskMR patientsHazards modelMitraClipPatientsFurther adjustmentLaboratory databasePropensity scorePatient matching
2008
High-risk myocardial infarction in the young: The VALsartan In Acute myocardial iNfarcTion (VALIANT) trial
Anderson RE, Pfeffer MA, Thune JJ, McMurray JJ, Califf RM, Velazquez E, White HD, Rouleau JL, Skali H, Maggioni A, Solomon SD. High-risk myocardial infarction in the young: The VALsartan In Acute myocardial iNfarcTion (VALIANT) trial. American Heart Journal 2008, 155: 706-711. PMID: 18371480, DOI: 10.1016/j.ahj.2007.11.016.Peer-Reviewed Original ResearchMeSH KeywordsAdultAge FactorsAgedAngiotensin II Type 1 Receptor BlockersAngiotensin-Converting Enzyme InhibitorsCardiovascular DiseasesDiabetes ComplicationsFemaleHumansHypertensionKaplan-Meier EstimateMaleMiddle AgedMortalityMultivariate AnalysisMyocardial InfarctionProportional Hazards ModelsRisk FactorsSex FactorsSmokingSurvivorsTetrazolesValineValsartanConceptsAcute myocardial infarctionAcute Myocardial Infarction trialMyocardial Infarction trialRisk factorsMyocardial infarctionHigh-risk myocardial infarctionCardiovascular event ratesInfluence of hypertensionMultivariate Cox regressionPrognostic risk factorsHistory of MICardiovascular outcomesCurrent smokersLess diabetesYounger patientsCox regressionPost-AMIAdvanced ageRelative riskYoung survivorsAge groupsHypertensionEvent ratesPatientsOutcomes