2015
Revascularization in Severe Left Ventricular Dysfunction
Velazquez EJ, Bonow RO. Revascularization in Severe Left Ventricular Dysfunction. Journal Of The American College Of Cardiology 2015, 65: 615-624. PMID: 25677320, DOI: 10.1016/j.jacc.2014.10.070.Peer-Reviewed Original ResearchConceptsLeft ventricular systolic dysfunctionVentricular systolic dysfunctionShort-term riskSurgical revascularizationSystolic dysfunctionSevere left ventricular systolic dysfunctionCoronary artery bypass graft surgeryArtery bypass graft surgeryHigh-risk patient populationBypass graft surgeryReduced ejection fractionCornerstone of treatmentHigh-risk patientsMitral valve surgerySurgical ventricular reconstructionGreater short-term riskImplantable device therapyQuality of lifeMultivessel diseaseGraft surgeryValve surgerySurgery needDevice therapyEjection fractionHeart failure
2014
Surgical Revascularization Is Associated With Maximal Survival in Patients With Ischemic Mitral Regurgitation
Castleberry AW, Williams JB, Daneshmand MA, Honeycutt E, Shaw LK, Samad Z, Lopes RD, Alexander JH, Mathew JP, Velazquez EJ, Milano CA, Smith PK. Surgical Revascularization Is Associated With Maximal Survival in Patients With Ischemic Mitral Regurgitation. Circulation 2014, 129: 2547-2556. PMID: 24744275, PMCID: PMC4142433, DOI: 10.1161/circulationaha.113.005223.Peer-Reviewed Original ResearchMeSH KeywordsAgedCoronary Artery BypassDatabases, BibliographicFemaleFollow-Up StudiesHeart Valve Prosthesis ImplantationHumansKaplan-Meier EstimateMaleMiddle AgedMitral ValveMitral Valve InsufficiencyMyocardial IschemiaMyocardial RevascularizationPercutaneous Coronary InterventionProportional Hazards ModelsRetrospective StudiesRisk FactorsSeverity of Illness IndexStentsConceptsIschemic mitral regurgitationPercutaneous coronary interventionMitral valve repairSignificant coronary artery diseaseSevere ischemic mitral regurgitationCoronary artery diseaseMitral regurgitationCoronary interventionValve repairMedical treatmentArtery diseaseTreatment strategiesLower mortalityMultivariable Cox proportional hazards analysisCox proportional hazards analysisCoronary artery bypassMitral valve surgeryKaplan-Meier methodProportional hazards analysisMitral regurgitation severitySurgical revascularizationArtery bypassValve surgeryOptimal treatmentCABG