2019
Association between systolic ejection time and outcomes in heart failure by ejection fraction
Patel PA, Ambrosy AP, Phelan M, Alenezi F, Chiswell K, Van Dyke MK, Tomfohr J, Honarpour N, Velazquez EJ. Association between systolic ejection time and outcomes in heart failure by ejection fraction. European Journal Of Heart Failure 2019, 22: 1174-1182. PMID: 31863532, PMCID: PMC7493053, DOI: 10.1002/ejhf.1659.Peer-Reviewed Original ResearchConceptsSystolic ejection timeEjection fractionHeart failureClinical outcomesVentricular systolic ejection timeOutpatient transthoracic echocardiogramReduced ejection fractionTertiary referral centerMultivariable logistic regressionHFrEF patientsHF patientsReferral centerTransthoracic echocardiogramAmbulatory patientsHF populationEjection timeEligibility criteriaLogistic regressionPatientsOutcomesAssociationHFpEFEchocardiogramHigh-Density Lipoprotein Particle Subfractions in Heart Failure With Preserved or Reduced Ejection Fraction
Hunter WG, McGarrah RW, Kelly JP, Khouri MG, Craig DM, Haynes C, Felker GM, Hernandez AF, Velazquez EJ, Kraus WE, Shah SH. High-Density Lipoprotein Particle Subfractions in Heart Failure With Preserved or Reduced Ejection Fraction. Journal Of The American College Of Cardiology 2019, 73: 177-186. PMID: 30654890, DOI: 10.1016/j.jacc.2018.10.059.Peer-Reviewed Original ResearchConceptsLipoprotein particle subfractionsHeart failureEjection fractionTotal HDLSmall HDLMajor adverse cardiac eventsVentricular end-diastolic pressureHDL-P sizeAdverse cardiac eventsReduced ejection fractionEnd-diastolic pressureCox proportional hazardsStrict inclusion criteriaCATHGEN biorepositoryDiastolic dysfunctionAdverse eventsCardiac eventsSequential patientsCardiac catheterizationEndothelial functionMultivariable analysisPrognostic utilityAdverse outcomesClinical covariatesHFpEF
2017
Measures of Ventricular-Arterial Coupling and Incident Heart Failure With Preserved Ejection Fraction: A Matched Case-Control Analysis
Lekavich CL, Barksdale DJ, Wu JR, Neelon V, Crandell J, Velazquez EJ. Measures of Ventricular-Arterial Coupling and Incident Heart Failure With Preserved Ejection Fraction: A Matched Case-Control Analysis. Journal Of Cardiac Failure 2017, 23: 659-665. PMID: 28716687, PMCID: PMC5585062, DOI: 10.1016/j.cardfail.2017.07.395.Peer-Reviewed Original ResearchConceptsVentricular-arterial couplingControl groupEchocardiographic markersEjection fractionHeart failureControl subjectsCase groupHigher oddsConditional logistic regression analysisMatched Case-Control AnalysisDate of echocardiographyIncident heart failureConditional logistic regressionLogistic regression analysisCase-control analysisTimes higher oddsIncident HFpEFAtrial diameterTransthoracic echocardiogramProspective studyStudy cohortMortality implicationsUse of EESHFpEFVentricular elastance