2015
Severity of Remodeling, Myocardial Viability, and Survival in Ischemic LV Dysfunction After Surgical Revascularization
Bonow RO, Castelvecchio S, Panza JA, Berman DS, Velazquez EJ, Michler RE, She L, Holly TA, Desvigne-Nickens P, Kosevic D, Rajda M, Chrzanowski L, Deja M, Lee KL, White H, Oh JK, Doenst T, Hill JA, Rouleau JL, Menicanti L, Investigators S. Severity of Remodeling, Myocardial Viability, and Survival in Ischemic LV Dysfunction After Surgical Revascularization. JACC Cardiovascular Imaging 2015, 8: 1121-1129. PMID: 26363840, PMCID: PMC4633018, DOI: 10.1016/j.jcmg.2015.03.013.Peer-Reviewed Original ResearchMeSH KeywordsAgedCoronary Artery BypassCoronary Artery DiseaseEchocardiography, StressFemaleHumansKaplan-Meier EstimateMaleMiddle AgedMyocardiumPredictive Value of TestsProportional Hazards ModelsProspective StudiesRecovery of FunctionRisk FactorsStroke VolumeTime FactorsTissue SurvivalTomography, Emission-Computed, Single-PhotonTreatment OutcomeUnited StatesVentricular Dysfunction, LeftVentricular Function, LeftVentricular RemodelingConceptsEnd-systolic volume indexEnd-systolic volumeEffect of CABGIschemic LV dysfunctionMedical therapyMyocardial viabilityLV dysfunctionViable myocardiumLV end-systolic volume indexMedian end-systolic volume indexSmaller end-systolic volumeCoronary artery bypassLV systolic dysfunctionMarker of severityCoronary artery diseaseLeft ventricular remodelingPre-specified criteriaSingle photon emissionSTICH trialSurgical revascularizationArtery bypassDobutamine echocardiographySystolic dysfunctionArtery diseaseIschemic cardiomyopathyInfluence of QRS infarct score and QRS duration prior to transcatheter aortic valve replacement on follow-up left ventricular end systolic volume in patients with new persistent left bundle branch block
Hannink LG, Wagner GS, Kisslo J, Alenezi FA, Shaw LK, Hofmann P, Zusterzeel R, Phelan M, Velazquez EJ, Gorgels AP. Influence of QRS infarct score and QRS duration prior to transcatheter aortic valve replacement on follow-up left ventricular end systolic volume in patients with new persistent left bundle branch block. Journal Of Electrocardiology 2015, 48: 637-642. PMID: 25959263, DOI: 10.1016/j.jelectrocard.2015.04.010.Peer-Reviewed Original ResearchMeSH KeywordsAged, 80 and overAortic Valve StenosisBundle-Branch BlockDiagnosis, Computer-AssistedEchocardiographyElectrocardiographyFemaleFollow-Up StudiesHumansMalePrognosisReproducibility of ResultsRetrospective StudiesRisk AssessmentSensitivity and SpecificityStroke VolumeTranscatheter Aortic Valve ReplacementTreatment OutcomeConceptsLeft bundle branch blockTranscatheter aortic valve replacementPersistent left bundle branch blockVentricular end-systolic volumeAortic valve replacementBundle branch blockEnd-systolic volumeQRS durationInfarct scoreValve replacementVentricular functionBranch blockNew-onset left bundle branch blockLeft ventricular end-systolic volumeNew left bundle branch blockLeft ventricular functionLarger study populationStrict inclusion criteriaSuch predictive valueQRS scoreSystolic volumeInclusion criteriaStudy populationCardiac conditionsPredictive valueImpact of surgical ventricular reconstruction on sphericity index in patients with ischaemic cardiomyopathy: follow‐up from the STICH trial
Choi J, Daly RC, Lin G, Lahr BD, Wiste HJ, Beaver TM, Iacovoni A, Malinowski M, Friedrich I, Rouleau JL, Favaloro RR, Sopko G, Lang IM, White HD, Milano CA, Jones RH, Lee KL, Velazquez EJ, Oh JK. Impact of surgical ventricular reconstruction on sphericity index in patients with ischaemic cardiomyopathy: follow‐up from the STICH trial. European Journal Of Heart Failure 2015, 17: 453-463. PMID: 25779355, PMCID: PMC4664050, DOI: 10.1002/ejhf.256.Peer-Reviewed Original ResearchConceptsSurgical ventricular reconstructionSVR groupSphericity indexVentricular reconstructionTreatment strategiesCoronary artery bypass graft surgeryIschemic Heart Failure (STICH) trialArtery bypass graft surgeryLV end-systolic volumeBypass graft surgeryHeart Failure TrialLV filling pressureEnd-systolic volumeIschemic cardiomyopathy patientsSmaller LV volumesLower sphericity indexImproved LVEFSTICH trialGraft surgeryWorse survivalIschemic cardiomyopathySurgical treatmentClinical outcomesFailure TrialMitral regurgitation
2012
Insights from the STICH trial: Change in left ventricular size after coronary artery bypass grafting with and without surgical ventricular reconstruction
Michler RE, Rouleau JL, Al-Khalidi HR, Bonow RO, Pellikka PA, Pohost GM, Holly TA, Oh JK, Dagenais F, Milano C, Wrobel K, Pirk J, Ali IS, Jones RH, Velazquez EJ, Lee KL, Di Donato M, Investigators S. Insights from the STICH trial: Change in left ventricular size after coronary artery bypass grafting with and without surgical ventricular reconstruction. Journal Of Thoracic And Cardiovascular Surgery 2012, 146: 1139-1145.e6. PMID: 23111018, PMCID: PMC3810307, DOI: 10.1016/j.jtcvs.2012.09.007.Peer-Reviewed Original ResearchConceptsEnd-systolic volume indexCoronary artery bypassSurgical ventricular reconstructionVentricular reconstructionArtery bypassVolume indexSurvival benefitML/Ischemic heart failureSignificant survival benefitEnd-systolic volumeLeft ventricular volumeSTICH trialPostoperative reductionHeart failureImproved survivalSurgical treatmentClinical benefitVentricular sizeImaging assessmentTreatment groupsVentricular volumePatientsBypassTrial data
2007
Mitral regurgitation in myocardial infarction complicated by heart failure, left ventricular dysfunction, or both: prognostic significance and relation to ventricular size and function
Amigoni M, Meris A, Thune JJ, Mangalat D, Skali H, Bourgoun M, Warnica JW, Barvik S, Arnold JM, Velazquez EJ, Van de Werf F, Ghali J, McMurray JJ, Køber L, Pfeffer MA, Solomon SD. Mitral regurgitation in myocardial infarction complicated by heart failure, left ventricular dysfunction, or both: prognostic significance and relation to ventricular size and function. European Heart Journal 2007, 28: 326-333. PMID: 17251259, DOI: 10.1093/eurheartj/ehl464.Peer-Reviewed Original ResearchMeSH KeywordsAgedCardiac VolumeDisease ProgressionEchocardiography, Doppler, ColorElectrocardiographyFemaleHeart FailureHumansMaleMiddle AgedMitral Valve InsufficiencyMyocardial InfarctionObserver VariationPrognosisProspective StudiesRandomized Controlled Trials as TopicRisk FactorsVentricular Dysfunction, LeftVentricular RemodelingConceptsProgression of MRBaseline mitral regurgitationHeart failureMitral regurgitationAcute myocardial infarctionMyocardial infarctionVentricular sizeMR severityHigh-risk myocardial infarctionModerate-severe mitral regurgitationBaseline MR severityWorse LV functionEnd-systolic volumeLarger LV volumesRegurgitant jet areaAtrial area ratioCV mortalityHF hospitalizationCardiovascular outcomesSystolic dysfunctionVentricular dysfunctionEjection fractionIndependent predictorsClinical outcomesLV function
2006
Association of QRS duration and outcomes after myocardial infarction: the VALIANT trial
Yerra L, Anavekar N, Skali H, Zelenkofske S, Velazquez E, McMurray J, Pfeffer M, Solomon SD. Association of QRS duration and outcomes after myocardial infarction: the VALIANT trial. Heart Rhythm 2006, 3: 313-316. PMID: 16500304, DOI: 10.1016/j.hrthm.2005.11.024.Peer-Reviewed Original ResearchMeSH KeywordsAgedAngiotensin-Converting Enzyme InhibitorsAntihypertensive AgentsCohort StudiesElectrocardiographyFemaleFollow-Up StudiesHeart VentriclesHumansMaleMiddle AgedMyocardial InfarctionPrognosisStroke VolumeSurvival RateTetrazolesTreatment OutcomeValineValsartanVentricular Dysfunction, LeftConceptsQRS durationSudden deathCV deathAdverse outcomesMyocardial infarctionPost-myocardial infarction settingUnivariate relative riskLeft ventricular dysfunctionHeart failure patientsSymptoms of HFAcute myocardial infarctionDevelopment of HFEnd-systolic volumeLarger ventricular volumesQRS duration prolongationRecurrent MICardiovascular deathInitial electrocardiogramVentricular dysfunctionAcute MIFailure patientsSystolic functionEjection fractionIndependent predictorsClinical outcomes