2023
MECHANISTIC EVALUATION OF AN AI-DRIVEN CLINICAL DECISION SUPPORT TOOL TO PERSONALIZE THE USE OF ANATOMICAL TESTING IN SUSPECTED CORONARY ARTERY DISEASE
Oikonomou E, Suchard M, Miller E, Velazquez E, Khera R. MECHANISTIC EVALUATION OF AN AI-DRIVEN CLINICAL DECISION SUPPORT TOOL TO PERSONALIZE THE USE OF ANATOMICAL TESTING IN SUSPECTED CORONARY ARTERY DISEASE. Journal Of The American College Of Cardiology 2023, 81: 1360. DOI: 10.1016/s0735-1097(23)01804-1.Peer-Reviewed Original Research
2020
LIMITED TESTING FOR CORONARY ARTERY DISEASE IN PATIENTS WITH NEW-ONSET HEART FAILURE: FINDINGS FROM GET WITH THE GUIDELINES - HEART FAILURE
O'Connor K, Brophy T, Fonarow G, Blankstein R, Swaminathan R, Xu H, Matsouaka R, Albert N, Velazquez E, Yancy C, Heidenreich P, Hernandez A, DeVore A. LIMITED TESTING FOR CORONARY ARTERY DISEASE IN PATIENTS WITH NEW-ONSET HEART FAILURE: FINDINGS FROM GET WITH THE GUIDELINES - HEART FAILURE. Journal Of The American College Of Cardiology 2020, 75: 866. DOI: 10.1016/s0735-1097(20)31493-5.Peer-Reviewed Original ResearchPrevention of cardiovascular disease for historically marginalized racial and ethnic groups living with HIV: A narrative review of the literature
Muiruri C, Longenecker CT, Meissner EG, Okeke NL, Pettit AC, Thomas K, Velazquez E, Bloomfield GS. Prevention of cardiovascular disease for historically marginalized racial and ethnic groups living with HIV: A narrative review of the literature. Progress In Cardiovascular Diseases 2020, 63: 142-148. PMID: 32057785, PMCID: PMC7237291, DOI: 10.1016/j.pcad.2020.02.006.Peer-Reviewed Original ResearchMeSH KeywordsAnti-HIV AgentsCardiovascular DiseasesComorbidityHealth Status DisparitiesHealthcare DisparitiesHIV InfectionsHIV Long-Term SurvivorsHumansPreventive Health ServicesPrognosisProtective FactorsRace FactorsRisk AssessmentRisk FactorsSocial Determinants of HealthSocial MarginalizationSocioeconomic FactorsViral LoadVulnerable PopulationsConceptsHuman immunodeficiency virusCardiovascular diseaseComorbid human immunodeficiency virusNarrative reviewSocial determinantsRacial disparitiesCommon social determinantsEthnic disparities persistEthnic groupsCVD morbidityImmunodeficiency virusClinical practiceTranslation of researchClinical researchDisparities persistDiseaseHealthDisparitiesGroupMorbidityReviewPersonsPrevention
2018
HFrEF other treatment: revascularization
Velazquez E, Petrie M. HFrEF other treatment: revascularization. 2018, 1881-1884. DOI: 10.1093/med/9780198784906.003.0431.Peer-Reviewed Original ResearchRight Ventricular Longitudinal Strain Reproducibility Using Vendor-Dependent and Vendor-Independent Software
Il'Giovine ZJ, Mulder H, Chiswell K, Arges K, Tomfohr J, Hashmi A, Velazquez EJ, Kisslo JA, Samad Z, Rajagopal S. Right Ventricular Longitudinal Strain Reproducibility Using Vendor-Dependent and Vendor-Independent Software. Journal Of The American Society Of Echocardiography 2018, 31: 721-732.e5. PMID: 29525250, PMCID: PMC6825401, DOI: 10.1016/j.echo.2018.01.008.Peer-Reviewed Original ResearchConceptsVendor-independent softwarePeak systolic longitudinal strainRight ventricular functionSingle-center studySystolic longitudinal strainMulticenter clinical trialCongenital heart diseaseRepeated-measures analysisRVLS valuesPulmonary hypertensionVentricular functionVendor-specific softwareHeart diseaseClinical trialsEchocardiographic scansClinical practiceLongitudinal strainWidespread variabilityDiseaseGlobal strainDifferent ultrasound scannersEffect of scannerWide variabilityRegional strainPossible interactions
2017
Approaches to Sustainable Capacity Building for Cardiovascular Disease Care in Kenya
Barasa FA, Vedanthan R, Pastakia SD, Crowe SJ, Aruasa W, Sugut WK, White R, Ogola ES, Bloomfield GS, Velazquez EJ. Approaches to Sustainable Capacity Building for Cardiovascular Disease Care in Kenya. Cardiology Clinics 2017, 35: 145-152. PMID: 27886785, DOI: 10.1016/j.ccl.2016.08.014.Peer-Reviewed Original ResearchConceptsCardiovascular disease careHealth care infrastructureDiseases of povertyMiddle-income countriesDisease careCardiovascular diseaseNoncommunicable diseasesTherapeutic strategiesDiagnostic capacityHigh-quality medicationsCare infrastructureEpidemic levelsHealth careDiseasePhysical injuryCareTraffic accidents
2016
Functional Mitral Regurgitation: Appraising the Evidence Behind Recommended Treatment Strategies
Samad Z, Velazquez EJ. Functional Mitral Regurgitation: Appraising the Evidence Behind Recommended Treatment Strategies. Current Cardiology Reports 2016, 18: 128. PMID: 27796864, DOI: 10.1007/s11886-016-0808-8.Peer-Reviewed Original ResearchTackling NCD in LMIC Achievements and Lessons Learned From the NHLBI–UnitedHealth Global Health Centers of Excellence Program
Engelgau M, Sampson U, Rabadan-Diehl C, Smith R, Miranda J, Bloomfield G, Belis D, Narayan K, National Health L, Rubinstein A, He J, Alam D, Peters D, Wu Y, Yan L, Merson M, Ramirez M, Caballero B, Xavier D, Yusuf S, Prabhakaran D, Narayan K, Kimaiyo S, Velazquez E, Denman C, Cornejo E, de Zapien J, Rosales C, Miranda J, Gilman R, Levitt N, Gaziano T, Ghannem H, Laatikainen T, Rabadan-Diehl C, Engelgau M, Belis D, Sampson U, Smith R, Dianis N, Wolbach T, Matta G, Gutierrez L, Elorriaga N, Poggio R, Irazola V, Bazzano L, Bhuiya A, Wazed A, Khan A, Siddiquee A, Islam A, Khan J, Uddin J, Hasan K, Khanam M, Yunus M, Chowdhury M, Monalisa N, Alam N, Streatfield P, Ahmed S, Parvin S, Ali T, Niessen L, Hossain M, Koehlmoos T, Standing H, Lucas H, Bleich S, Anderson G, Trujillo A, Mirelman A, Hao J, Zhang J, Tian M, Huang P, Luo R, Fang W, Li X, Feng X, Li Z, Deal K, Peterson E, DeLong E, Zhou B, Shi J, Neal B, Jan S, Li N, McMahon S, Zhang J, Sun J, Elliot P, Zhao Y, Zhang Y, Yao C, Sun N, Han Q, Shen R, Niu W, Wang Y, Ke Y, Huang Y, Leeder S, Lopez A, Zhang R, Yu Y, Roman A, Mendoza C, Roche D, Mejicano G, Cordova M, Kroker M, Fort M, Letona P, Kanter R, Garcia R, Murillo S, Chacon V, Montero R, Lopez E, Peña L, Castro M, Dengo A, Ulate E, Alvarado N, Sibrian J, Alegria A, Gutierrez A, Fontes F, Sigamani A, Kamath D, Xavier F, Deepthi K, Anupama M, Mathu N, George N, Rahul P, Pais P, Girish P, Thomas S, Usha T, Thomas T, Joshi R, Chidambaram N, Gupta R, Chow C, Pogue J, O'Donnell M, Devereaux P, Misquith D, Agrawal T, Fathima F, Reddy K, Shivashankar R, Ajay V, Khan H, Kadir M, Masood M, Fatmi Z, Krishnan A, Singh K, Tandon N, Khadgawat R, Menon V, Sethi B, Unnikrishnan A, Hutcheson M, Ali M, Cunningham S, Patel S, Gujral U, Desai A, Mohan D, Pradeepa R, Mohan V, Viswanathan V, Sahay R, Shah S, Bantwal G, Varthakavi P, Nair M, Akwanalo C, Lagat D, Barasa F, Koech M, Sugut W, Korir B, Mosol P, Ali S, Sherman C, Carter J, Bloomfield G, Binanay C, Vedanthan R, Bernabé-Ortiz A, León-Velarde F, Smith G, Málaga G, García H, Casas J, Sacksteder K, Smeeth L, Huicho L, Rivera M, Gamboa R, Ebrahim S, Montori V, Wise R, Checkley W, Diette G, Nojilana B, Majikela-Dlangamandla B, Sylvester C, Malan J, Murphy K, Steyn K, van Niekerk L, Mash R, Puoane T, Kim G, Pandya A, Abrahams-Gessel S, Rhode H, Pather M, Andrade A, Garcia B, Velasco C, Medina D, Bravo D, Munguia D, Bateman E, Castro F, Schneider H, Ibarra I, Zulu J, Felix J, Tribe K, Bobrow K, Fairall L, Folb N, Murillo N, Pacheco N, Rodriguez P, Navarro P, Flores R, Van Zyl Smit R, Meddoza R, Surka S, Van Haght S, Hernandez Y, Tsolekile L, Jeridi G, Harrabi I, Maatoug J, Boughammoura L, Chaieb L, Mrizek N, Gaha R, Limam K, Amimi S, Gaha K, Gamra H, Al'Absi M, Vartiainen E, Moore C, Spillan D, Cooper K, Mitchell M, Kirby R, Gao Y, Aluko E. Tackling NCD in LMIC Achievements and Lessons Learned From the NHLBI–UnitedHealth Global Health Centers of Excellence Program. Global Heart 2016, 11: 5-15. PMID: 27102018, PMCID: PMC4843818, DOI: 10.1016/j.gheart.2015.12.016.Peer-Reviewed Original ResearchConceptsHealth centersUnitedHealth GroupNoncommunicable disease burdenPriority health issuesBiomedical Research CentreMiddle-income countriesBlood InstituteLung diseaseNational HeartDisease burdenHealth issuesSpecific country settingsCountry settingsProgram’s overall goalSettingFuture investigatorsResearch CenterLungCenterDiseaseNCD
2015
Building Sustainable Capacity for Cardiovascular Care at a Public Hospital in Western Kenya
Binanay CA, Akwanalo CO, Aruasa W, Barasa FA, Corey GR, Crowe S, Esamai F, Einterz R, Foster MC, Gardner A, Kibosia J, Kimaiyo S, Koech M, Korir B, Lawrence JE, Lukas S, Manji I, Maritim P, Ogaro F, Park P, Pastakia SD, Sugut W, Vedanthan R, Yanoh R, Velazquez EJ, Bloomfield GS. Building Sustainable Capacity for Cardiovascular Care at a Public Hospital in Western Kenya. Journal Of The American College Of Cardiology 2015, 66: 2550-2560. PMID: 26653630, PMCID: PMC4680855, DOI: 10.1016/j.jacc.2015.09.086.Peer-Reviewed Original ResearchConceptsMiddle-income countriesPublic referral hospitalCardiovascular disease deathsWorld Health Organization frameworkResource-limited settingsHealth care systemReferral hospitalSubspecialty careDisease deathsCardiovascular healthChronic diseasesCardiovascular diseaseCardiovascular careMedical CenterCardiovascular servicesInfectious diseasesHealth systemCare systemDiseaseHealth partnershipsHospitalStepwise approachCareWestern KenyaAcademic partnershipsGenetic mutations in African patients with atrial fibrillation: Rationale and design of the Study of Genetics of Atrial Fibrillation in an African Population (SIGNAL)
Bloomfield GS, Temu TM, Akwanalo CO, Chen PS, Emonyi W, Heckbert SR, Koech MM, Manji I, Shen C, Vatta M, Velazquez EJ, Wessel J, Kimaiyo S, Inui TS. Genetic mutations in African patients with atrial fibrillation: Rationale and design of the Study of Genetics of Atrial Fibrillation in an African Population (SIGNAL). American Heart Journal 2015, 170: 455-464.e5. PMID: 26385028, PMCID: PMC4575772, DOI: 10.1016/j.ahj.2015.06.008.Peer-Reviewed Original ResearchConceptsValvular atrial fibrillationNonvalvular atrial fibrillationValvular heart diseaseAtrial fibrillationHeart diseaseCurrent tobacco smokingHistory of strokeCase-control studyGroup morbidityGenetic associationTobacco smokingSaharan AfricaMean ageAfrican patientsCardiovascular diseaseClinical phenotypingFibrillationPrimary analysisPatientsControl populationGenetic testingMorbidityDiseaseGenetic mutationsMost participantsImplementation of Management Strategies for Diabetes and Hypertension From Local to Global Health in Cardiovascular Diseases
Bloomfield GS, Wang TY, Boulware LE, Califf RM, Hernandez AF, Velazquez EJ, Peterson ED, Li JS. Implementation of Management Strategies for Diabetes and Hypertension From Local to Global Health in Cardiovascular Diseases. Global Heart 2015, 10: 31-38. PMID: 25754564, PMCID: PMC4754665, DOI: 10.1016/j.gheart.2014.12.010.Peer-Reviewed Original ResearchConceptsCardiovascular diseaseNetwork-based careFuture cardiovascular diseasePopulation risk stratificationUniversity Health CentreSuccessful treatment interventionsChronic conditionsHealth centersTreatment interventionsHypertensionDiabetesImproved healthGlobal healthMajor causal factorDiseaseHealthManagement strategiesCausal factorsPrevalenceCare
2011
Chronic noncommunicable cardiovascular and pulmonary disease in sub-Saharan Africa: An academic model for countering the epidemic
Bloomfield GS, Kimaiyo S, Carter EJ, Binanay C, Corey GR, Einterz RM, Tierney WM, Velazquez EJ. Chronic noncommunicable cardiovascular and pulmonary disease in sub-Saharan Africa: An academic model for countering the epidemic. American Heart Journal 2011, 161: 842-847. PMID: 21570512, PMCID: PMC3093664, DOI: 10.1016/j.ahj.2010.12.020.Peer-Reviewed Original ResearchConceptsPulmonary diseaseChronic diseasesNoncommunicable diseasesChronic noncommunicable diseasesMaternal diseaseWorldwide epidemicPulmonary medicinePatient careWorldwide deathsClinical researchDiseaseCardiovascular medicineMajor causeUnprecedented burdenInternational academic partnershipsCareSaharan AfricaWestern KenyaEpidemicBurdenAcademic partnershipsTraining curriculumResearch training curriculumMedicineMyocardial Viability and Survival in Ischemic Left Ventricular Dysfunction
Bonow RO, Maurer G, Lee KL, Holly TA, Binkley PF, Desvigne-Nickens P, Drozdz J, Farsky PS, Feldman AM, Doenst T, Michler RE, Berman DS, Nicolau JC, Pellikka PA, Wrobel K, Alotti N, Asch FM, Favaloro LE, She L, Velazquez EJ, Jones RH, Panza JA. Myocardial Viability and Survival in Ischemic Left Ventricular Dysfunction. New England Journal Of Medicine 2011, 364: 1617-1625. PMID: 21463153, PMCID: PMC3290901, DOI: 10.1056/nejmoa1100358.Peer-Reviewed Original ResearchMeSH KeywordsAgedCardiovascular DiseasesCombined Modality TherapyCoronary Artery BypassCoronary Artery DiseaseEchocardiography, StressFemaleFollow-Up StudiesHeart FailureHumansKaplan-Meier EstimateMaleMiddle AgedMyocardial IschemiaMyocardiumProportional Hazards ModelsStatistics, NonparametricTomography, Emission-Computed, Single-PhotonVentricular Dysfunction, LeftConceptsCoronary artery diseaseVentricular dysfunctionMedical therapyMyocardial viabilityArtery diseaseViable myocardiumSurvival benefitBaseline variablesIschemic left ventricular dysfunctionDifferential survival benefitSubstudy of patientsCoronary artery bypassLeft ventricular dysfunctionDobutamine echocardiographyUnderwent assessmentPatientsCABGDysfunctionTreatment assignmentTherapyMyocardiumDiseaseGreater likelihoodMortalityTrials
2004
Usefulness of myocardial viability or ischemia in predicting long-term survival for patients with severe left ventricular dysfunction undergoing revascularization
Liao L, Cabell CH, Jollis JG, Velazquez EJ, Smith WT, Anstrom KJ, Pappas PA, Ryan T, Kisslo JA, Landolfo CK. Usefulness of myocardial viability or ischemia in predicting long-term survival for patients with severe left ventricular dysfunction undergoing revascularization. The American Journal Of Cardiology 2004, 93: 1275-1279. PMID: 15135703, DOI: 10.1016/j.amjcard.2004.01.071.Peer-Reviewed Original ResearchConceptsSevere left ventricular dysfunctionLeft ventricular dysfunctionVentricular dysfunctionDobutamine stress echocardiographySignificant survival advantageLong-term survivalCoronary diseaseStress echocardiographyViable myocardiumMyocardial viabilityPrognostic powerSurvival advantagePatientsRevascularizationDysfunctionEchocardiographyIschemiaMyocardiumDiseaseMonths
2002
A Reappraisal of Myocardial Viability Testing in Patients with Coronary Artery Disease and Left Ventricular Dysfunction: Can Meta-Analysis Be Trusted?
Bourque J, Velazquez E, Borges-Neto S, Hasselblad V, O’Connor C. A Reappraisal of Myocardial Viability Testing in Patients with Coronary Artery Disease and Left Ventricular Dysfunction: Can Meta-Analysis Be Trusted? Cardiology 2002, 2: 204-205. DOI: 10.1159/000065943.Commentaries, Editorials and Letters