2013
Muscular effects of statins in the elderly female: a review
Bhardwaj S, Selvarajah S, Schneider E. Muscular effects of statins in the elderly female: a review. Clinical Interventions In Aging 2013, Volume 8: 47-59. PMID: 23355775, PMCID: PMC3552608, DOI: 10.2147/cia.s29686.Peer-Reviewed Original ResearchMeSH KeywordsAgedAgingCell DeathComorbidityDrug InteractionsFemaleGenetic Predisposition to DiseaseHumansHydroxymethylglutaryl-CoA Reductase InhibitorsIncidenceMuscular DiseasesMyositisPolyisoprenyl PhosphatesQuality of LifeRhabdomyolysisSesquiterpenesSex FactorsUbiquinoneConceptsMuscle disordersElderly femalesMuscular effectsMuscle-related side effectsIncidence of statinLong-term outcomesOverall patient complianceOlder adult womenOverall incidenceCardiovascular healthElderly womenPatient complianceStatinsSide effectsAdult womenOlder individualsYoung individualsAppropriate useDisordersSignificant reductionVulnerable groupsIncidenceWomenFemalesPatients
2011
Premorbid Statin Use Is Associated With Improved Survival and Functional Outcomes in Older Head-Injured Individuals
Schneider E, Efron D, MacKenzie E, Rivara F, Nathens A, Jurkovich G. Premorbid Statin Use Is Associated With Improved Survival and Functional Outcomes in Older Head-Injured Individuals. Journal Of Trauma And Acute Care Surgery 2011, 71: 815-819. PMID: 21986733, DOI: 10.1097/ta.0b013e3182319de5.Peer-Reviewed Original ResearchMeSH KeywordsAgedCardiovascular DiseasesComorbidityCraniocerebral TraumaFemaleGlasgow Coma ScaleHospital MortalityHumansHydroxymethylglutaryl-CoA Reductase InhibitorsMaleRegression AnalysisRiskTreatment OutcomeConceptsPreinjury statin usePremorbid statin useAbbreviated Injury ScoreStatin useFunctional outcomeCardiovascular comorbiditiesStatin usersFunctional recoveryHead traumaMonths postinjuryExtended Glasgow Outcome Scale scoreGlasgow Outcome Scale scoreExtended Glasgow Outcome ScaleHours of admissionTraumatic brain injury victimsGlasgow Outcome ScaleSevere head traumaTime of injuryPossible protective agentsHead-injured individualsBrain injury victimsHospital deathHospital mortalityInjury characteristicsInjury score
2008
Preinjury Statin Use is Associated With Improved In-Hospital Survival in Elderly Trauma Patients
Efron D, Sorock G, Haut E, Chang D, Schneider E, MacKenzie E, Cornwell E, Jurkovich G. Preinjury Statin Use is Associated With Improved In-Hospital Survival in Elderly Trauma Patients. Journal Of Trauma And Acute Care Surgery 2008, 64: 66-74. PMID: 18188101, DOI: 10.1097/ta.0b013e31815b842a.Peer-Reviewed Original ResearchMeSH KeywordsAgedCardiovascular DiseasesCohort StudiesComorbidityConfounding Factors, EpidemiologicFemaleHospital MortalityHumansHydroxymethylglutaryl-CoA Reductase InhibitorsLogistic ModelsMaleMultivariate AnalysisOdds RatioRetrospective StudiesWounds and InjuriesConceptsPreinjury statin useElderly trauma patientsStatin useElderly patientsHospital mortalityTrauma patientsRetrospective observational cohort studyNew Injury Severity ScoreCerebral midline shiftIn-Hospital SurvivalMultivariable adjusted oddsBeta-blocker useObservational cohort studySignificant survival benefitGlutaryl-CoA reductase inhibitorsInjury Severity ScoreGlasgow Coma ScaleTime of injurySevere traumatic injurySample of patientsTrauma center treatmentCardiovascular comorbiditiesHospital deathStatin therapyCohort study