2024
RATES OF PRETERM BIRTH AND LOW BIRTH WEIGHT IN IVF COMPARED TO UNASSISTED CONCEPTION: A COMPARISON OF 36,930 IVF-CONCEIVED WITH 79,391,393 UNASSISTED PREGNANCIES OVER 20 YEARS (2003-2022)
Reig A, Seli E. RATES OF PRETERM BIRTH AND LOW BIRTH WEIGHT IN IVF COMPARED TO UNASSISTED CONCEPTION: A COMPARISON OF 36,930 IVF-CONCEIVED WITH 79,391,393 UNASSISTED PREGNANCIES OVER 20 YEARS (2003-2022). Fertility And Sterility 2024, 122: e280. DOI: 10.1016/j.fertnstert.2024.07.874.Peer-Reviewed Original Research
2021
Emerging follicular activation strategies to treat women with poor ovarian response and primary ovarian insufficiency
Reig A, Herraiz S, Pellicer A, Seli E. Emerging follicular activation strategies to treat women with poor ovarian response and primary ovarian insufficiency. Current Opinion In Obstetrics & Gynecology 2021, 33: 241-248. PMID: 33896920, DOI: 10.1097/gco.0000000000000703.Peer-Reviewed Original ResearchConceptsPoor ovarian responsePrimary ovarian insufficiencyLive birthsOngoing pregnancyOvarian responseOvarian insufficiencyAutologous platelet-rich plasmaBone marrow transplantFemale reproductive agingPlatelet-rich plasmaIntraovarian injectionOvarian transplantationMarrow transplantReproductive agingFertility treatmentReproductive medicineWomenPregnancyBirthInsufficiencyPrevious reportsPreliminary studyMechanical disruptionAkt stimulationCutting-edge strategiesNoninvasive prenatal testing in women undergoing in vitro fertilization with preimplantation genetic testing
Klimczak AM, Seli E, Scott RT. Noninvasive prenatal testing in women undergoing in vitro fertilization with preimplantation genetic testing. Current Opinion In Obstetrics & Gynecology 2021, 33: 184-187. PMID: 33797422, DOI: 10.1097/gco.0000000000000707.Peer-Reviewed Original ResearchConceptsPreimplantation genetic testingGenetic testingNoninvasive prenatal testing resultsPositive test resultsPrenatal screening toolPositive predictive valuePrenatal testing resultsPregnant womenEuploid embryosPredictive valueNoninvasive prenatal testingScreening toolWomenRecent evidenceIVFPrenatal testingPGTPregnancyPrevalencePrenatalTesting
2019
The association between assisted reproductive technologies and low birth weight.
Reig A, Seli E. The association between assisted reproductive technologies and low birth weight. Current Opinion In Obstetrics & Gynecology 2019, 31: 183-187. PMID: 30893135, DOI: 10.1097/gco.0000000000000535.Peer-Reviewed Original ResearchConceptsLow birth weightFresh embryo transferFrozen embryo transferBirth weightNumber of embryosEmbryo transferReproductive technologiesART-conceived pregnanciesComparable birth weightMain risk factorsEndometrial preparationPerinatal outcomesMultiple gestationsRisk factorsAssisted reproductionPrematurityNewbornsIncidenceRecent studiesPregnancyGestationWeight
2011
Preterm deliveries that result from multiple pregnancies associated with assisted reproductive technologies in the USA: a cost analysis
Bromer JG, Ata B, Seli M, Lockwood CJ, Seli E. Preterm deliveries that result from multiple pregnancies associated with assisted reproductive technologies in the USA: a cost analysis. Current Opinion In Obstetrics & Gynecology 2011, 23: 168-173. PMID: 21372712, DOI: 10.1097/gco.0b013e32834551cd.Peer-Reviewed Original ResearchConceptsMultiple pregnanciesPreterm deliveryPreterm infantsNumber of embryosInfant deliveryAssisted reproductive technology cyclesElective single embryo transferART live birthsReproductive technology cyclesSingle embryo transferFinancial burdenART neonatesART twinsMedical complicationsART cyclesLive birthsSubstantial burdenMean costPregnancyEmbryo transferART tripletsInfantsHealthcare expendituresHealth science policyReproductive technologies
2010
Assisted reproduction in a patient with Klippel-Trenaunay syndrome: management of thrombophilia and consumptive coagulopathy
Martin JR, Pels SG, Paidas M, Seli E. Assisted reproduction in a patient with Klippel-Trenaunay syndrome: management of thrombophilia and consumptive coagulopathy. Journal Of Assisted Reproduction And Genetics 2010, 28: 217-219. PMID: 21188495, PMCID: PMC3082665, DOI: 10.1007/s10815-010-9526-0.Peer-Reviewed Original ResearchConceptsKlippel-Trenaunay syndromeConsumptive coagulopathyChronic consumptive coagulopathyManagement of thrombophiliaDeep venous thrombosisExtensive port-wine stainsPort-wine stainsObstetrical riskThromboembolic eventsVenous thrombosisBone hypertrophyLymphatic malformationsCongenital malformationsSoft tissueAssisted reproductionCoagulopathyWine stainsPregnancyPatientsSyndromeMalformationsGestational surrogatesHypercoagulabilityThrombosisComplicationsReceiver operating characteristic (ROC) analysis of day 5 morphology grading and metabolomic Viability Score on predicting implantation outcome
Seli E, Bruce C, Botros L, Henson M, Roos P, Judge K, Hardarson T, Ahlström A, Harrison P, Henman M, Go K, Acevedo N, Siques J, Tucker M, Sakkas D. Receiver operating characteristic (ROC) analysis of day 5 morphology grading and metabolomic Viability Score on predicting implantation outcome. Journal Of Assisted Reproduction And Genetics 2010, 28: 137-144. PMID: 21063765, PMCID: PMC3059520, DOI: 10.1007/s10815-010-9501-9.Peer-Reviewed Original ResearchConceptsSingle embryo transferFetal cardiac activityMorphologic gradingViability scoreWeeks of gestationPregnancy outcomesIVF outcomesIVF centerCharacteristic analysisMorphology gradingImplantation outcomesEmbryo transferDay 5ResultsThe areaConclusionsOur findingsPregnancyEmbryo culture medium samplesCardiac activityComposite scoreScoresCleavage rateOutcomesCulture medium samplesEmbryo morphologyGradingEconomics of assisted reproductive technologies
Ata B, Seli E. Economics of assisted reproductive technologies. Current Opinion In Obstetrics & Gynecology 2010, 22: 183-188. PMID: 20125015, DOI: 10.1097/gco.0b013e3283373c13.Peer-Reviewed Original ResearchConceptsART utilization ratesNumber of embryosMultiple pregnanciesPocket expensesPrematurity-related complicationsAchievement of pregnancySingle embryo transferCost of ARTReproductive technologiesReimbursement plansNational healthcare expendituresTreatment attemptsART utilizationEconomic burdenEmbryo transferPregnancyHealthcare expendituresReimbursement policiesPublic reimbursementDownstream costsIndustrialized worldUtilization rateComplicationsPatientsPhysiciansThird party reproduction and the aging couple
Luk J, Greenfeld DA, Seli E. Third party reproduction and the aging couple. Maturitas 2010, 66: 389-396. PMID: 20451337, DOI: 10.1016/j.maturitas.2010.03.024.Peer-Reviewed Original ResearchConceptsThird-party reproductionOocyte donationFirst pregnancyInfertility treatmentSignificant success rateAverage ageOocyte donorsSocial workersMore womenCommon formSuccess rateReproductive technologiesLate 30sPregnancyEarly 40sPartner's advancesAgeFemale agePartiesUnited StatesPhysical involvementDonationUterusGratifying experienceNurses
2008
Noninvasive metabolomic profiling of embryo culture media using proton nuclear magnetic resonance correlates with reproductive potential of embryos in women undergoing in vitro fertilization
Seli E, Botros L, Sakkas D, Burns DH. Noninvasive metabolomic profiling of embryo culture media using proton nuclear magnetic resonance correlates with reproductive potential of embryos in women undergoing in vitro fertilization. Fertility And Sterility 2008, 90: 2183-2189. PMID: 18842260, DOI: 10.1016/j.fertnstert.2008.07.1739.Peer-Reviewed Original ResearchMeSH KeywordsBiomarkersCulture MediaEmbryo Culture TechniquesEmbryo ImplantationEmbryo TransferEmbryo, MammalianEmbryonic DevelopmentFemaleFertilization in VitroHumansLive BirthMagnetic Resonance SpectroscopyMetabolomicsPredictive Value of TestsPregnancyPregnancy RateProtonsRetrospective StudiesSensitivity and SpecificityTreatment OutcomeConceptsEmbryo culture mediumNoninvasive metabolomic profilingMetabolomic profilesMetabolomic profilingReproductive technology programViability indexNuclear magnetic resonance metabolomic profilingRetrospective studyART treatmentMAIN OUTCOMEReproductive outcomesCulture mediumDay 3NMR metabolomic profilesGlutamate concentrationMultivariate analysisPregnancy