Not All Seeds Are Created Equal: Seed Classification Is Predictive of Outcomes in Retinoblastoma
Berry JL, Bechtold M, Shah S, Zolfaghari E, Reid M, Jubran R, Kim JW. Not All Seeds Are Created Equal: Seed Classification Is Predictive of Outcomes in Retinoblastoma. Ophthalmology 2017, 124: 1817-1825. PMID: 28655537, DOI: 10.1016/j.ophtha.2017.05.034.Peer-Reviewed Original ResearchMeSH KeywordsAntineoplastic Agents, AlkylatingAntineoplastic Combined Chemotherapy ProtocolsCarboplatinChildChild, PreschoolCryotherapyEtoposideFemaleFollow-Up StudiesHumansInfantInfusions, IntravenousIntravitreal InjectionsLaser CoagulationMaleMelphalanNeoplasm SeedingRetinal NeoplasmsRetinoblastomaRetrospective StudiesSalvage TherapyVincristineVitreous BodyConceptsIntra-arterial chemotherapyIntravitreal melphalanIntravenous chemotherapyVitreous seedingSalvage rateRetrospective reviewIVM injectionsOverall globe salvage ratePrimary intra-arterial chemotherapyGlobe salvage rateNonrandomized retrospective reviewOutcome of retinoblastomaRecurrent vitreous seedingPrimary outcome measureActive retinoblastomaVitreous seedsGlobe salvageIntravitreal chemotherapySingle centerIntravitreal injectionMore injectionsGrade 3Outcome measuresSecondary measuresEffective treatmentTreatment Outcomes of Focal Laser Consolidation during Chemoreduction for Group B Retinoblastoma
Kim JW, Aziz HA, McGovern K, Zolfaghari E, Jubran RF, Murphree AL, Berry JL. Treatment Outcomes of Focal Laser Consolidation during Chemoreduction for Group B Retinoblastoma. Ophthalmology Retina 2017, 1: 361-368. PMID: 31047562, PMCID: PMC7448755, DOI: 10.1016/j.oret.2017.01.014.Peer-Reviewed Original ResearchGlobe salvage rateGroup B tumorsTumor sizeB tumorsChorioretinal scarsSalvage rateTreatment outcomesPosterior fundusSingle-institution retrospective chart reviewScar sizeOverall globe salvage rateInitial laser treatmentMedian percent reductionRetrospective chart reviewGroup B eyesEnd of treatmentVertical diameterOriginal tumor sizeFinal scar sizeAssociation of timingLaser treatmentPerifoveal lesionsSystemic chemoreductionSystemic chemotherapyChart review