2019
Decreases in Blood Pressure During Thrombectomy Are Associated With Larger Infarct Volumes and Worse Functional Outcome
Petersen NH, Ortega-Gutierrez S, Wang A, Lopez GV, Strander S, Kodali S, Silverman A, Zheng-Lin B, Dandapat S, Sansing LH, Schindler JL, Falcone GJ, Gilmore EJ, Amin H, Cord B, Hebert RM, Matouk C, Sheth KN. Decreases in Blood Pressure During Thrombectomy Are Associated With Larger Infarct Volumes and Worse Functional Outcome. Stroke 2019, 50: 1797-1804. PMID: 31159701, PMCID: PMC6787912, DOI: 10.1161/strokeaha.118.024286.Peer-Reviewed Original ResearchConceptsFinal infarct volumeWorse functional outcomeInfarct volumeEndovascular thrombectomyFunctional outcomeOcclusion strokeCerebral infarction 2b/3 reperfusionPressure reductionLarge vessel intracranial occlusionsGreater infarct growthBlood pressure reductionComprehensive stroke centerPercent of patientsBlood pressure managementLarger infarct volumesModified Rankin ScaleRankin Scale scoreMultivariable logistic regressionRelative hypotensionSustained hypotensionInfarct progressionNinety patientsInfarct growthIschemic penumbraIschemic stroke
2012
Impact of Prolonged Periodic Epileptiform Discharges on Coma Prognosis
Ong C, Gilmore E, Claassen J, Foreman B, Mayer SA. Impact of Prolonged Periodic Epileptiform Discharges on Coma Prognosis. Neurocritical Care 2012, 17: 39-44. PMID: 22700361, DOI: 10.1007/s12028-012-9728-7.Peer-Reviewed Original ResearchConceptsRecovery of consciousnessComatose patientsElectrographic seizuresCEEG monitoringEpileptiform dischargesAdmission Glasgow Coma Scale scoreGlasgow Coma Scale scoreHypoxic-ischemic encephalopathyGlasgow Outcome ScaleTime of dischargeContinuous EEG monitoringNumber of AEDsPeriodic epileptiform dischargesComa prognosisResultsMean ageMedian durationCommon diagnosisIntracerebral hemorrhageFocal hypermetabolismNeuro-ICUSubarachnoid hemorrhageFrequent findingOutcome ScaleClinical significanceLikelihood of survival