2017
Ictal-Interictal Continuum: When to Worry About the Continuous Electroencephalography Pattern
Cormier J, Maciel CB, Gilmore EJ. Ictal-Interictal Continuum: When to Worry About the Continuous Electroencephalography Pattern. Seminars In Respiratory And Critical Care Medicine 2017, 38: 793-806. PMID: 29262437, DOI: 10.1055/s-0037-1607987.Peer-Reviewed Original ResearchConceptsNonconvulsive status epilepticusIctal-interictal continuumNonconvulsive seizuresEEG patternsSecondary brain injuryContinuous electroencephalography monitoringCritical care physiciansClear clinical significanceIIC patternsIll patientsStatus epilepticusCare physiciansCEEG monitoringElectroencephalography monitoringSeizure riskBrain injuryGuideline statementsClinical dilemmaClinical significanceNeuronal stressClinical approachDefinitive guidelinesElectroencephalography patternsPotential associationEarly detection
2015
Acute brain failure in severe sepsis: a prospective study in the medical intensive care unit utilizing continuous EEG monitoring
Gilmore EJ, Gaspard N, Choi HA, Cohen E, Burkart KM, Chong DH, Claassen J, Hirsch LJ. Acute brain failure in severe sepsis: a prospective study in the medical intensive care unit utilizing continuous EEG monitoring. Intensive Care Medicine 2015, 41: 686-694. PMID: 25763756, DOI: 10.1007/s00134-015-3709-1.Peer-Reviewed Original ResearchConceptsNonconvulsive seizuresSevere sepsisEEG reactivityPeriodic dischargesLate seizuresSOFA scoreAPACHE IIFunctional outcomeContinuous sedationHigh riskLower riskMedical intensive care unitLong-term cognitive outcomesPresence of sedationAPACHE II scoreGood functional outcomeNonconvulsive status epilepticusIntensive care unitContinuous EEG monitoringAcute brain failureAcademic medical centerNew epilepsyII scoreClinical seizuresMedical ICU