2024
Atypical Interpersonal Problem-Solving and Resting-state Functional Connectivity in Adolescents with Maltreatment Experience
Gerin M, Viding E, Puetz V, Armbruster-Genc D, Rankin G, McCrory E. Atypical Interpersonal Problem-Solving and Resting-state Functional Connectivity in Adolescents with Maltreatment Experience. Current Neuropharmacology 2024, 22: 290-301. PMID: 37818587, PMCID: PMC10788892, DOI: 10.2174/1570159x22666231002145440.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentBrainChildGyrus CinguliHumansMagnetic Resonance ImagingMental DisordersMental HealthNeural PathwaysConceptsResting-state functional connectivityPosterior cingulate cortexMedial prefrontal cortexMental health symptomsMaltreatment experiencesSocial functioningLingual gyrusFunctional connectivityHealth symptomsInterpersonal problem-solving skillsRetrosplenial cortexElevated mental health symptomsDefault mode network hubInterpersonal problem solvingPoor social functioningAdverse environmental experiencesProblem-solving performanceNon-maltreated peersProblem-solving skillsExperiences of abuseSeed-based analysisNeurocognitive processingNeurocognitive functioningMental health disordersEarly adversity
2023
A systematic review of childhood maltreatment and resting state functional connectivity
Gerin M, Viding E, Herringa R, Russell J, McCrory E. A systematic review of childhood maltreatment and resting state functional connectivity. Developmental Cognitive Neuroscience 2023, 64: 101322. PMID: 37952287, PMCID: PMC10665826, DOI: 10.1016/j.dcn.2023.101322.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAmygdalaBrainBrain MappingChildChild AbuseGyrus CinguliHumansMagnetic Resonance ImagingConceptsResting-state functional connectivityAnterior cingulate cortexFunctional connectivityCingulate cortexChildhood maltreatmentAltered functional connectivityState functional connectivityDorsal anterior cingulate cortexNegative psychiatric outcomesVentral anterior cingulate cortexDorsolateral prefrontal cortexRsFC alterationsAltered connectivityInclusion criteriaAmygdala connectivityNineteen studiesPsychiatric outcomesFuture symptomsSystematic reviewBrain regionsClinical disordersBrain circuitsAnterior insulaPrefrontal cortexMaltreatment exposure
2022
Altered reward and effort processing in children with maltreatment experience: a potential indicator of mental health vulnerability
Armbruster-Genç D, Valton V, Neil L, Vuong V, Freeman Z, Packer K, Kiffin M, Roiser J, Viding E, McCrory E. Altered reward and effort processing in children with maltreatment experience: a potential indicator of mental health vulnerability. Neuropsychopharmacology 2022, 47: 1063-1070. PMID: 35149765, PMCID: PMC8832084, DOI: 10.1038/s41386-022-01284-7.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentChildChild AbuseGyrus CinguliHumansLongitudinal StudiesMagnetic Resonance ImagingMental HealthRewardConceptsFunctional magnetic resonance imagingInternalizing symptomsHistory of maltreatmentAnterior cingulate cortexEffort processingEffort-based decision-making taskDecision-making taskEffort-based decisionElevated internalizing symptomsNon-maltreated childrenImpact of maltreatmentMental health vulnerabilitiesFuture internalizing symptomsNeural indicesACC activationAltered rewardBehavioral indicesMaltreatment experiencesLatent vulnerabilityCingulate cortexEffort sensitivityGroup differencesRewardMaltreatmentLongitudinal study
2018
Evidence for Depressogenic Spontaneous Thoughts and Altered Resting-State Connectivity in Adolescents With a Maltreatment History
Hoffmann F, Viding E, Puetz V, Gerin M, Sethi A, Rankin G, McCrory E. Evidence for Depressogenic Spontaneous Thoughts and Altered Resting-State Connectivity in Adolescents With a Maltreatment History. Journal Of The American Academy Of Child & Adolescent Psychiatry 2018, 57: 687-695.e4. PMID: 30196872, DOI: 10.1016/j.jaac.2018.05.020.Peer-Reviewed Original Research
2015
Grey Matter Volumes in Children with Conduct Problems and Varying Levels of Callous-Unemotional Traits
Sebastian C, De Brito S, McCrory E, Hyde Z, Lockwood P, Cecil C, Viding E. Grey Matter Volumes in Children with Conduct Problems and Varying Levels of Callous-Unemotional Traits. Research On Child And Adolescent Psychopathology 2015, 44: 639-649. PMID: 26364620, PMCID: PMC4830891, DOI: 10.1007/s10802-015-0073-0.Peer-Reviewed Original Research
2013
Cortical Thickness, Surface Area, and Gyrification Abnormalities in Children Exposed to Maltreatment: Neural Markers of Vulnerability?
Kelly P, Viding E, Wallace G, Schaer M, De Brito S, Robustelli B, McCrory E. Cortical Thickness, Surface Area, and Gyrification Abnormalities in Children Exposed to Maltreatment: Neural Markers of Vulnerability? Biological Psychiatry 2013, 74: 845-852. PMID: 23954109, DOI: 10.1016/j.biopsych.2013.06.020.Peer-Reviewed Original ResearchConceptsCortical thicknessLingual gyrusAnterior cingulateLeft middle temporal areaSuperior frontal gyrusBrain volume differencesAtypical neural structureCortical surface areaMiddle temporal areaPrevious neuroimaging studiesGyrification abnormalitiesTemporal lobePsychiatric disordersLocal gyrificationPsychiatric riskHistory of abuseStructural abnormalitiesTemporal areaClinical disordersBiological markersOrbitofrontal cortexPrefrontal cortexBrain structuresGyrusNeuroimaging studiesNeural responses to fearful eyes in children with conduct problems and varying levels of callous–unemotional traits
Sebastian C, McCrory E, Dadds M, Cecil C, Lockwood P, Hyde Z, De Brito S, Viding E. Neural responses to fearful eyes in children with conduct problems and varying levels of callous–unemotional traits. Psychological Medicine 2013, 44: 99-109. PMID: 23510564, DOI: 10.1017/s0033291713000482.Peer-Reviewed Original ResearchConceptsFunctional magnetic resonance imagingSubgenual anterior cingulate cortexImportant translational implicationsNeural responsesAnterior cingulate cortexAmygdala responseMagnetic resonance imagingFearful eyesConduct problemsTrial participantsEye conditionsCingulate cortexCortex responsesResonance imagingEvidence baseAmygdala reactivityTranslational implicationsHeterogeneous groupTD controlsEyesChildrenFear recognition deficitsNeural levelParticipantsLow levels
2010
Effects of stressful life events on human brain structure: A longitudinal voxel-based morphometry study
Papagni S, Benetti S, Arulanantham S, McCrory E, McGuire P, Mechelli A. Effects of stressful life events on human brain structure: A longitudinal voxel-based morphometry study. Stress 2010, 14: 227-232. PMID: 21034297, DOI: 10.3109/10253890.2010.522279.Peer-Reviewed Original ResearchConceptsGray matter volumePost-traumatic stress disorderStressful life eventsNumber of SLEsPsychiatric diagnosisLongitudinal voxel-based morphometry studyVoxel-based morphometry studyGray matter changesFormal psychiatric diagnosisMagnetic resonance imagingRisk of illnessLife eventsMatter changesParahippocampal gyrusMatter volumeAnterior cingulateHealthy adultsMorphometry studyMental disordersResonance imagingBrain regionsBrain structuresStress disorderAnatomical scansTime points