Conditioned Hallucinations and Prior Overweighting Are State-Sensitive Markers of Hallucination Susceptibility
Kafadar E, Fisher VL, Quagan B, Hammer A, Jaeger H, Mourgues C, Thomas R, Chen L, Imtiaz A, Sibarium E, Negreira AM, Sarisik E, Polisetty V, Benrimoh D, Sheldon AD, Lim C, Mathys C, Powers AR. Conditioned Hallucinations and Prior Overweighting Are State-Sensitive Markers of Hallucination Susceptibility. Biological Psychiatry 2022, 92: 772-780. PMID: 35843743, PMCID: PMC10575690, DOI: 10.1016/j.biopsych.2022.05.007.Peer-Reviewed Original ResearchConceptsCH rateIncoming sensory evidenceSensory evidencePerceptual statesTask performanceComputational psychiatrySubset of participantsPrior expectationsHallucination severityBehavioral dataSymptom severityPast experienceStable measureHallucinationsPsychotic symptomsHallucination frequencyTaskSymptom expressionBayesian modelState markerHallucinatorsNonhallucinatorsOverweightingPerceptionSymptom riskMeasuring Voluntary Control Over Hallucinations: The Yale Control Over Perceptual Experiences (COPE) Scales
Mourgues C, Hammer A, Fisher V, Kafadar E, Quagan B, Bien C, Jaeger H, Thomas R, Sibarium E, Negreira AM, Sarisik E, Polisetty V, Eken H, Imtiaz A, Niles H, Sheldon AD, Powers AR. Measuring Voluntary Control Over Hallucinations: The Yale Control Over Perceptual Experiences (COPE) Scales. Schizophrenia Bulletin 2022, 48: 673-683. PMID: 35089361, PMCID: PMC9077437, DOI: 10.1093/schbul/sbab144.Peer-Reviewed Original ResearchConceptsAuditory verbal hallucinationsPositive clinical outcomesClinical outcomesPilot studyQuality of lifeConvergent validityFrequent auditory verbal hallucinationsExperiences ScaleClinical measuresConventional treatmentNovel interventionsSymptom severitySignificant distressClinical scalesComprehensive batteryPsychosis-spectrum diagnosisVerbal hallucinationsSound psychometric propertiesAVH contentVoluntary controlPsychometric propertiesHallucinationsControl ScaleValidation studyIntervention