Structural correlates of cognitive impairment in normal pressure hydrocephalus
Peterson KA, Mole TB, Keong NCH, DeVito EE, Savulich G, Pickard JD, Sahakian BJ. Structural correlates of cognitive impairment in normal pressure hydrocephalus. Acta Neurologica Scandinavica 2018, 139: 305-312. PMID: 30428124, PMCID: PMC6492129, DOI: 10.1111/ane.13052.Peer-Reviewed Original ResearchMeSH KeywordsAdultBrainCognitive DysfunctionFemaleHumansHydrocephalus, Normal PressureMagnetic Resonance ImagingMaleMiddle AgedConceptsNormal pressure hydrocephalusNPH patientsNeuropsychiatric symptomsPressure hydrocephalusNeuropsychiatric measuresNeuropsychological testsStructure volumesStriatal volume lossDeep gray matter structuresMeasures of apathySubcortical deep gray matter structuresT1-weighted magnetic resonanceGray matter structuresNAcc volumeSmaller caudateNeuropsychiatric changesHealthy controlsPathological basisNPH groupCaudate nucleusNucleus accumbensCaudate volumePatientsSubcortical regionsCognitive impairment