2024
A Digital Cognitive Behavioral Therapy Program for Adults With Alcohol Use Disorder
Kiluk B, Benitez B, DeVito E, Frankforter T, LaPaglia D, O’Malley S, Nich C. A Digital Cognitive Behavioral Therapy Program for Adults With Alcohol Use Disorder. JAMA Network Open 2024, 7: e2435205. PMID: 39325452, PMCID: PMC11428014, DOI: 10.1001/jamanetworkopen.2024.35205.Peer-Reviewed Original ResearchConceptsCognitive behavioral therapyDigital cognitive behavioral therapyAlcohol use disorderAlcohol useCBT programUse disorderCognitive behavioral therapy programCurrent alcohol use disorderTreatment-seeking adultsBehavioral therapy programEvidence-based treatmentsBaseline to 6-month follow-upRates of alcohol useReducing alcohol useTreatment periodRandomized clinical trialsBehavioral therapyOutpatient substancePercentage of daysOutpatient treatmentIntention-to-treat analysisIndividual counselingStudy periodFollow-upIntention-to-treat
2023
Enrollment of Spanish-speaking Latinx adults in clinical trials: Five lessons learned from a randomized study in substance use treatment
Jaramillo Y, DeVito E, Silva M, Rojas Perez O, Benitez B, Frankforter T, Leon K, Paris M. Enrollment of Spanish-speaking Latinx adults in clinical trials: Five lessons learned from a randomized study in substance use treatment. Drug And Alcohol Dependence 2023, 253: 111016. PMID: 37952354, PMCID: PMC10842233, DOI: 10.1016/j.drugalcdep.2023.111016.Peer-Reviewed Original ResearchConceptsRandomized clinical trialsClinical trialsLatinx individualsClinical trial participantsSubstance use treatmentRandomized studySubstance use concernsTrial participantsClinical researchUse treatmentSubstance useTrialsLatinx adultsTreatmentLatinx participantsUse concernsParticipantsRecruitment sitesUnited States
2022
Religiosity and Spirituality in Latinx Individuals with Substance Use Disorders: Association with Treatment Outcomes in a Randomized Clinical Trial
Jaramillo Y, DeVito EE, Frankforter T, Silva MA, Añez LM, Kiluk BD, Carroll KM, Paris M. Religiosity and Spirituality in Latinx Individuals with Substance Use Disorders: Association with Treatment Outcomes in a Randomized Clinical Trial. Journal Of Religion And Health 2022, 61: 4139-4154. PMID: 35305222, PMCID: PMC9482997, DOI: 10.1007/s10943-022-01544-2.Peer-Reviewed Original ResearchConceptsCognitive behavioral therapy treatmentWeb-based cognitive behavioral therapySubstance useCognitive behavioral therapyBehavioral therapy treatmentLatinx adultsMeasures of abstinenceSpanish-language versionSubstance use disordersTreatment outcomesBehavioral therapyBehavior QuestionnaireLatinx individualsProtective factorsAbstinence outcomesUse disordersReligiosity scoresLatinx populationsSix-month followClinical trialsReligiosityRandomized clinical trialsAdditional researchReligious backgroundAdults
2019
Double‐Blind Placebo‐Controlled Trial of Galantamine for Methadone‐Maintained Individuals With Cocaine Use Disorder: Secondary Analysis of Effects on Illicit Opioid Use
Carroll KM, DeVito EE, Yip SW, Nich C, Sofuoglu M. Double‐Blind Placebo‐Controlled Trial of Galantamine for Methadone‐Maintained Individuals With Cocaine Use Disorder: Secondary Analysis of Effects on Illicit Opioid Use. American Journal On Addictions 2019, 28: 238-245. PMID: 31165574, PMCID: PMC9078084, DOI: 10.1111/ajad.12904.Peer-Reviewed Original ResearchConceptsMethadone-maintained individualsOpioid useSecondary analysisMultiple drugsConcurrent cocaine dependenceTrial of galantaminePlacebo-controlled trialDouble-blind placeboIllicit opioid useRandomized clinical trialsCocaine use disorderGalantamine's effectFuture trialsClinical trialsUrine specimenUrine specimensUse disordersOpioidsCholinesterase inhibitorsMaintenance settingCocaine useCocaine dependencePlaceboConcurrent useGalantamine
2017
Functional Neural Changes Following Behavioral Therapies and Disulfiram for Cocaine Dependence
DeVito EE, Dong G, Kober H, Xu J, Carroll KM, Potenza MN. Functional Neural Changes Following Behavioral Therapies and Disulfiram for Cocaine Dependence. Psychology Of Addictive Behaviors 2017, 31: 534-547. PMID: 28714728, PMCID: PMC5548432, DOI: 10.1037/adb0000298.Peer-Reviewed Original ResearchConceptsCognitive behavioral therapyContingency managementPrecentral gyrusNeural activityFrontal gyrusWhole-brain correlation analysesRandomized clinical trialsSample overallBeginning of treatmentForm of treatmentMedial frontal gyrusInferior parietal lobuleCocaine use disorderDifferent treatment componentsMedication daysClinical trialsTreatment outcomesUse disordersTreatment relateFunctional changesParietal lobuleGyrusTreatment componentsGreater reductionTreatment
2014
Gender differences in clinical outcomes for cocaine dependence: Randomized clinical trials of behavioral therapy and disulfiram
DeVito EE, Babuscio TA, Nich C, Ball SA, Carroll KM. Gender differences in clinical outcomes for cocaine dependence: Randomized clinical trials of behavioral therapy and disulfiram. Drug And Alcohol Dependence 2014, 145: 156-167. PMID: 25457739, PMCID: PMC4268325, DOI: 10.1016/j.drugalcdep.2014.10.007.Peer-Reviewed Original ResearchConceptsRandomized clinical trialsClinical trialsClinical outcomesTreatment outcomesCocaine dependenceBehavioral therapyBehavioral treatment conditionsPoor treatment outcomesEvidence-based treatmentsGender differencesWidespread clinical implementationPoor outcomePharmacological treatmentMedication conditionAddiction pharmacotherapyCocaine useSecondary analysisBehavioral treatmentClinical implementationWomenCareful assessmentDisulfiramOutcomesTrialsMen
2011
A preliminary study of the neural effects of behavioral therapy for substance use disorders
DeVito EE, Worhunsky PD, Carroll KM, Rounsaville BJ, Kober H, Potenza MN. A preliminary study of the neural effects of behavioral therapy for substance use disorders. Drug And Alcohol Dependence 2011, 122: 228-235. PMID: 22041256, PMCID: PMC3296894, DOI: 10.1016/j.drugalcdep.2011.10.002.Peer-Reviewed Original ResearchConceptsComputer-assisted cognitive behavioral therapyBehavioral therapySubstance use disordersInferior frontal gyrusCognitive behavioral therapyMaintenance of addictionUse disordersSubstance use outcomesCognitive controlFrontal gyrusTest-retest conditionsNeural effectsComponent of treatmentAnterior cingulateImpulse controlNeural systemsSame taskUse outcomesBOLD signalSubstance useSubstance abuseStroopComparison groupRandomized clinical trialsHealthy controls