2018
Structural correlates of cognitive impairment in normal pressure hydrocephalus
Peterson KA, Mole TB, Keong NCH, DeVito EE, Savulich G, Pickard JD, Sahakian BJ. Structural correlates of cognitive impairment in normal pressure hydrocephalus. Acta Neurologica Scandinavica 2018, 139: 305-312. PMID: 30428124, PMCID: PMC6492129, DOI: 10.1111/ane.13052.Peer-Reviewed Original ResearchConceptsNormal pressure hydrocephalusNPH patientsNeuropsychiatric symptomsPressure hydrocephalusNeuropsychiatric measuresNeuropsychological testsStructure volumesStriatal volume lossDeep gray matter structuresMeasures of apathySubcortical deep gray matter structuresT1-weighted magnetic resonanceGray matter structuresNAcc volumeSmaller caudateNeuropsychiatric changesHealthy controlsPathological basisNPH groupCaudate nucleusNucleus accumbensCaudate volumePatientsSubcortical regionsCognitive impairment
2007
Caudate structural abnormalities in idiopathic normal pressure hydrocephalus
DeVito E, Salmond C, Owler B, Sahakian B, Pickard J. Caudate structural abnormalities in idiopathic normal pressure hydrocephalus. Acta Neurologica Scandinavica 2007, 116: 328-332. PMID: 17922726, DOI: 10.1111/j.1600-0404.2007.00906.x.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAtrophyBasal Ganglia DiseasesCaudate NucleusCerebrospinal Fluid PressureCorpus CallosumDisease ProgressionFemaleHumansHydrocephalus, Normal PressureImage Processing, Computer-AssistedIntracranial HypertensionLateral VentriclesMagnetic Resonance ImagingMaleMiddle AgedPredictive Value of TestsConceptsNormal pressure hydrocephalusPressure hydrocephalusIdiopathic normal pressure hydrocephalusManual volumetric analysisVoxel-based morphometric analysisCaudate nucleus volumeStructural volumetric changesINPH patientsReversible dementiaINPH groupHealthy controlsCaudate nucleusStructural abnormalitiesCognitive deficitsVolumetric analysisNucleus volumeHydrocephalusRegion of interestROI measurementsINPHMorphometric analysisAffective changes