Featured Publications
The Association Between Obstructive Sleep Apnea and Abnormal 82Rubidium Cardiac PET Perfusion Myocardial Flow Reserve
Aneni E, Thorn S, Feher A, Hong Chen J, Sinusas A, Yaggi H, Miller E. The Association Between Obstructive Sleep Apnea and Abnormal 82Rubidium Cardiac PET Perfusion Myocardial Flow Reserve. JACC Cardiovascular Imaging 2023, 16: 856-858. PMID: 36881426, PMCID: PMC10718199, DOI: 10.1016/j.jcmg.2022.11.024.Peer-Reviewed Original ResearchAtherosclerotic plaque in individuals without known cardiovascular disease but with established obstructive sleep apnea and at high risk of obstructive sleep apnea
Walia H, Khosla A, Saxena A, Aneni E, Ali S, Valero-Elizondo J, Cainzos-Achirica M, Feldman T, Fialkow J, Nasir K. Atherosclerotic plaque in individuals without known cardiovascular disease but with established obstructive sleep apnea and at high risk of obstructive sleep apnea. American Journal Of Preventive Cardiology 2023, 14: 100497. PMID: 37131984, PMCID: PMC10149201, DOI: 10.1016/j.ajpc.2023.100497.Peer-Reviewed Original ResearchObstructive sleep apneaCoronary plaquesHigh riskSleep apneaLower riskBerlin questionnaireRisk factorsCT angiographySignificant associationMultivariable logistic regression analysisCardiovascular risk factorsCVD risk factorsLarge U.S. cohortCoronary CT angiographyLogistic regression analysisPopulation-based sampleComposition of plaquesLogistic regression modelsOSA cohortOSA presenceCoronary atherosclerosisOSA severityOSA categoriesSubgroup analysisCardiovascular disease
2024
Association between high risk of obstructive sleep apnea and inflammatory markers in a population sample of young and middle-aged adults in the Miami Heart Study.
Khosla A, Nasir K, Saxena A, Aneni E, Ali S, Valero-Elizondo J, Cainzos-Achirica M, Feldman T, Fialkow J, Walia H. Association between high risk of obstructive sleep apnea and inflammatory markers in a population sample of young and middle-aged adults in the Miami Heart Study. Journal Of Clinical Sleep Medicine 2024 PMID: 38975989, DOI: 10.5664/jcsm.11274.Peer-Reviewed Original ResearchHigh risk of obstructive sleep apneaRisk of obstructive sleep apneaObstructive sleep apneaHs-CRPCardiovascular disease risk factorsFree of cardiovascular diseaseInflammatory markersHigh riskCardiovascular diseaseIL-6Sleep apneaLow risk of obstructive sleep apneaTNF-aObstructive sleep apnea screeningLow riskRisk factorsLevels of inflammatory markersLevels of hs-CRPTNF-a levelsCVD-free participantsHeart StudyBerlin questionnaireIndividuals free of cardiovascular diseaseSubclinical inflammationPoisson regression analysisLinks Between Obstructive Sleep Apnea and Myocardial Blood Flow Changes Impacting Adverse Cardiovascular Disease-related Outcomes
Aneni E, Sinusas A, Emokpae M, Thorn S, Yaggi H, Miller E. Links Between Obstructive Sleep Apnea and Myocardial Blood Flow Changes Impacting Adverse Cardiovascular Disease-related Outcomes. Current Cardiology Reports 2024, 26: 723-734. PMID: 38806976, DOI: 10.1007/s11886-024-02072-z.Peer-Reviewed Original ResearchObstructive sleep apneaCoronary microvascular dysfunctionAbnormal myocardial blood flowSevere obstructive sleep apneaMyocardial flow reserveMyocardial blood flowSleep apneaModerate to severe obstructive sleep apneaAbnormal myocardial flow reserveRecent FindingsRecent studiesDisease-related outcomesBlood flow changesMyocardial blood flow changesCardiovascular disease-related outcomesMicrovascular dysfunctionClinical impactCPAPReviewRecent studiesStructural abnormalitiesCoronary microcirculationFindingsRecent studiesFlow reserveCardiac workBlood flowApnea