Featured Publications
The risk of cardiometabolic disorders in lean non-alcoholic fatty liver disease: A longitudinal study
Aneni E, Bittencourt M, Teng C, Cainzos-Achirica M, Osondu C, Soliman A, Al-Mallah M, Buddoff M, Parise E, Santos R, Nasir K. The risk of cardiometabolic disorders in lean non-alcoholic fatty liver disease: A longitudinal study. American Journal Of Preventive Cardiology 2020, 4: 100097. PMID: 34327473, PMCID: PMC8315654, DOI: 10.1016/j.ajpc.2020.100097.Peer-Reviewed Original ResearchLean non-alcoholic fatty liver diseaseNon-alcoholic fatty liver diseaseFatty liver diseaseAlcohol Use Disorders Identification TestLean individualsAtherogenic dyslipidemiaElevated glucoseElevated BPLiver diseaseFatty liverCardiovascular risk stratificationYoung asymptomatic individualsHealth promotion evaluationDisorders Identification TestAppropriate preventive measuresMedian followNAFLD individualsCardiometabolic consequencesCardiometabolic disordersRisk stratificationAsymptomatic individualsHigh riskBlood samplesAnthropometric measuresPopulation cohortBlood pressure is associated with the presence and severity of nonalcoholic fatty liver disease across the spectrum of cardiometabolic risk
Aneni EC, Oni ET, Martin SS, Blaha MJ, Agatston AS, Feldman T, Veledar E, Conçeicao RD, Carvalho JA, Santos RD, Nasir K. Blood pressure is associated with the presence and severity of nonalcoholic fatty liver disease across the spectrum of cardiometabolic risk. Journal Of Hypertension 2015, 33: 1207-1214. PMID: 25693058, DOI: 10.1097/hjh.0000000000000532.Peer-Reviewed Original ResearchConceptsNonobese hypertensive patientsPrevalence of NAFLDMetabolic risk factorsHypertensive patientsNormal BPRisk factorsHigh Blood Pressure classificationNonalcoholic fatty liver diseaseHealthy middle-aged menBlood pressure groupJoint National CommitteeDevelopment of hypertensionFatty liver diseaseYearly physical examinationMiddle-aged menBlood pressure classificationBP controlPrehypertensive patientsCardiometabolic riskCross-sectional relationshipBlood pressureNAFLD severityLiver diseaseNormotensive individualsPhysical examination
2022
Cardiometabolic disorders, inflammation and the incidence of non-alcoholic fatty liver disease: A longitudinal study comparing lean and non-lean individuals
Aneni E, Saeed G, Bittencourt M, Cainzos-Achirica M, Osondu C, Budoff M, Parise E, Santos R, Nasir K. Cardiometabolic disorders, inflammation and the incidence of non-alcoholic fatty liver disease: A longitudinal study comparing lean and non-lean individuals. PLOS ONE 2022, 17: e0266505. PMID: 35385529, PMCID: PMC8985996, DOI: 10.1371/journal.pone.0266505.Peer-Reviewed Original ResearchConceptsNon-alcoholic fatty liver diseaseRisk of NAFLDElevated blood glucoseElevated blood pressureFatty liver diseaseBlood glucoseLean individualsBlood pressureCardiometabolic disordersPhysical inactivityWaist circumferenceLiver diseaseDevelopment of NAFLDHigh-sensitivity C-reactive proteinCardiovascular disease risk stratificationSensitivity C-reactive proteinCardiometabolic risk factorsAlcohol Use Disorders Identification TestC-reactive proteinMain exposure variableDisease risk stratificationHospital Israelita Albert EinsteinDisorders Identification TestAppropriate preventive measuresAtherogenic dyslipidemia
2020
Non-Alcoholic Fatty Liver Disease Modifies Serum Gamma-Glutamyl Transferase in Cigarette Smokers
Oni ET, Figueredo V, Aneni E, Veladar E, McEvoy JW, Blaha MJ, Blumenthal RS, Conceicao RD, Carvalho JAM, Santos RD, Nasir K. Non-Alcoholic Fatty Liver Disease Modifies Serum Gamma-Glutamyl Transferase in Cigarette Smokers. Journal Of Clinical Medicine Research 2020, 12: 472-482. PMID: 32849935, PMCID: PMC7430878, DOI: 10.14740/jocmr3932.Peer-Reviewed Original ResearchNon-alcoholic fatty liver diseaseGamma-glutamyl transferaseSerum gamma-glutamyl transferaseClinical cardiovascular diseaseHigh GGT levelsGGT levelsNAFLD statusOxidative stressAbsence of NAFLDPresence of NAFLDPrevalence of NAFLDFatty liver diseaseImpact of smokingCross-sectional associationsCV riskCardiovascular riskCurrent smokersCurrent smokingMultivariable adjustmentLiver diseaseCigarette smokersEffect modificationCardiovascular diseaseHealthy subjectsSmoking