Cell therapy of critical limb ischemia-problems and prospects.
Osipova O, Saaya S, Karpenko A, Zakian S, Aboian E. Cell therapy of critical limb ischemia-problems and prospects. Vasa 2019, 48: 461-471. PMID: 30969159, DOI: 10.1024/0301-1526/a000787.Peer-Reviewed Original ResearchMeSH KeywordsAmputation, SurgicalCell- and Tissue-Based TherapyCritical IllnessGenetic TherapyHumansIschemiaLimb SalvageTreatment OutcomeVascular Surgical ProceduresConceptsCritical limb ischemiaCell therapyStem cellsHuman trial dataGene therapyIndirect revascularizationSurgical revascularizationLimb ischemiaCLI treatmentCritical limbClinical trialsParacrine effectsFuture stem cellTherapyTrial dataAngiogenesis gene therapyVasculogenic propertiesProgenitor cellsPutative mechanismsRevascularizationCellsIschemiaPatientsActive substances