2024
Associations between parental psychopathology and youth functional emotion regulation brain networks
Karl V, Beck D, Eilertsen E, Morawetz C, Wiker T, Aksnes E, Norbom L, Ferschmann L, MacSweeney N, Voldsbekk I, Andreassen O, Westlye L, Gee D, Engen H, Tamnes C. Associations between parental psychopathology and youth functional emotion regulation brain networks. Developmental Cognitive Neuroscience 2024, 70: 101476. PMID: 39541797, DOI: 10.1016/j.dcn.2024.101476.Peer-Reviewed Original ResearchParental psychopathologyYouth psychopathologyEmotion regulationAssociated with children's emotion regulationResting-state functional magnetic resonance imaging dataAdolescent Brain Cognitive Development StudyIntergenerational transmission of psychopathologyAssociated with lower connectivityFunctional magnetic resonance imaging dataTransmission of psychopathologyChildren's emotion regulationCognitive Development StudyMagnetic resonance imaging dataParental mental healthPFC networksPsychopathologyBrain networksParental internalizingMediation analysisCognitive aspectsMental healthConnectivity patternsIntergenerational transmissionNetwork connectivityYouth
2021
Genetic variation in endocannabinoid signaling is associated with differential network‐level functional connectivity in youth
Sisk LM, Rapuano KM, Conley MI, Greene AS, Horien C, Rosenberg MD, Scheinost D, Constable RT, Glatt CE, Casey BJ, Gee DG. Genetic variation in endocannabinoid signaling is associated with differential network‐level functional connectivity in youth. Journal Of Neuroscience Research 2021, 100: 731-743. PMID: 34496065, PMCID: PMC8866205, DOI: 10.1002/jnr.24946.Peer-Reviewed Original ResearchConceptsEndocannabinoid signalingAllele carriersLower anxiety symptomsC385A polymorphismNetwork-level functional connectivityEnhanced endocannabinoid signalingLarge-scale resting-state brain networksAnxiety symptomsResting-state brain networksGenotype-associated differencesBrain networksFronto-amygdala connectivityFunctional connectionsCognitive Development StudyNetwork-level changesPotential protective factorsAdolescent Brain Cognitive Development (ABCD) studyEndocannabinoid systemNetwork-level differencesYounger ageFunctional connectivityProtective factorsNeural phenotypesAnxiety disordersNeural connectivity