Association of Maternal Prepregnancy Body Mass Index With Fetal Growth and Neonatal Thalamic Brain Connectivity Among Adolescent and Young Women
Spann MN, Scheinost D, Feng T, Barbato K, Lee S, Monk C, Peterson BS. Association of Maternal Prepregnancy Body Mass Index With Fetal Growth and Neonatal Thalamic Brain Connectivity Among Adolescent and Young Women. JAMA Network Open 2020, 3: e2024661. PMID: 33141162, PMCID: PMC7610195, DOI: 10.1001/jamanetworkopen.2020.24661.Peer-Reviewed Original ResearchConceptsMaternal prepregnancy BMIMaternal prepregnancy body mass indexPrepregnancy body mass indexNeonatal functional connectivityPrepregnancy BMIBody mass indexFetal growthFunctional connectivityFetal weightMass indexMAIN OUTCOMEHigher maternal prepregnancy body mass indexElectronic health record reviewAdverse long-term outcomesProspective longitudinal cohort studyColumbia University Irving Medical CenterBrain connectivityHigher maternal BMIHealth record reviewLong-term outcomesRoutine prenatal careLongitudinal cohort studyMajor health problemFetal head circumferenceTime of recruitmentIdentification of a brain fingerprint for overweight and obesity
Farruggia MC, van Kooten MJ, Perszyk EE, Burke MV, Scheinost D, Constable RT, Small DM. Identification of a brain fingerprint for overweight and obesity. Physiology & Behavior 2020, 222: 112940. PMID: 32417645, PMCID: PMC7321926, DOI: 10.1016/j.physbeh.2020.112940.Peer-Reviewed Original ResearchConceptsPercent body fatWaist circumferenceBody fatWhole-brain functional connectivityBrain network patternsGlucose toleranceBlood insulinObesityOverweightPathophysiological phenotypesFunctional connectivity networksFunctional connectivityMilkshake consumptionBrain correlatesBrain fingerprintsBMIAdiposityBrainCircumferenceConnectivity networksFatDiabetesPathophysiologyCentral roleInsulin