2020
Association of Maternal Prepregnancy Body Mass Index With Fetal Growth and Neonatal Thalamic Brain Connectivity Among Adolescent and Young Women
Spann MN, Scheinost D, Feng T, Barbato K, Lee S, Monk C, Peterson BS. Association of Maternal Prepregnancy Body Mass Index With Fetal Growth and Neonatal Thalamic Brain Connectivity Among Adolescent and Young Women. JAMA Network Open 2020, 3: e2024661. PMID: 33141162, PMCID: PMC7610195, DOI: 10.1001/jamanetworkopen.2020.24661.Peer-Reviewed Original ResearchConceptsMaternal prepregnancy BMIMaternal prepregnancy body mass indexPrepregnancy body mass indexNeonatal functional connectivityPrepregnancy BMIBody mass indexFetal growthFunctional connectivityFetal weightMass indexMAIN OUTCOMEHigher maternal prepregnancy body mass indexElectronic health record reviewAdverse long-term outcomesProspective longitudinal cohort studyColumbia University Irving Medical CenterBrain connectivityHigher maternal BMIHealth record reviewLong-term outcomesRoutine prenatal careLongitudinal cohort studyMajor health problemFetal head circumferenceTime of recruitment
2018
Maternal Immune Activation During the Third Trimester Is Associated with Neonatal Functional Connectivity of the Salience Network and Fetal to Toddler Behavior
Spann MN, Monk C, Scheinost D, Peterson BS. Maternal Immune Activation During the Third Trimester Is Associated with Neonatal Functional Connectivity of the Salience Network and Fetal to Toddler Behavior. Journal Of Neuroscience 2018, 38: 2877-2886. PMID: 29487127, PMCID: PMC5852665, DOI: 10.1523/jneurosci.2272-17.2018.Peer-Reviewed Original ResearchConceptsMaternal immune activationC-reactive proteinFetal heart rate variabilityNeonatal functional connectivityInterleukin-6Postmenstrual ageImmune activationSalience networkFunctional connectivityPsychiatric disordersCRP levelsEpidemiological studiesMaternal C-reactive proteinResting-state imaging dataC-reactive protein levelsMaternal CRP levelsMaternal IL-6Months postmenstrual agePrenatal maternal immune activationSame psychiatric disordersWeeks postmenstrual ageIL-6 levelsAlters functional connectivityAltered brain developmentSame gestational age