2015
Chemiexcitation of melanin derivatives induces DNA photoproducts long after UV exposure
Premi S, Wallisch S, Mano CM, Weiner AB, Bacchiocchi A, Wakamatsu K, Bechara EJ, Halaban R, Douki T, Brash DE. Chemiexcitation of melanin derivatives induces DNA photoproducts long after UV exposure. Science 2015, 347: 842-847. PMID: 25700512, PMCID: PMC4432913, DOI: 10.1126/science.1256022.Peer-Reviewed Original ResearchConceptsDark cyclobutane pyrimidine dimersExcited electronic statesUltraviolet photonsUV photonsElectronic statesTriplet stateSunlight-induced melanomaCytosine-containing cyclobutane pyrimidine dimersEnergy transferPhotonsPicosecondsElectronsUV exposureRadiationChemiexcitationEnergyStatePhotoproducts
2009
Influence of cytosine methylation on ultraviolet-induced cyclobutane pyrimidine dimer formation in genomic DNA
Rochette PJ, Lacoste S, Therrien JP, Bastien N, Brash DE, Drouin R. Influence of cytosine methylation on ultraviolet-induced cyclobutane pyrimidine dimer formation in genomic DNA. Mutation Research/Fundamental And Molecular Mechanisms Of Mutagenesis 2009, 665: 7-13. PMID: 19427505, DOI: 10.1016/j.mrfmmm.2009.02.008.Peer-Reviewed Original ResearchConceptsLigation-mediated PCRX chromosomeFMR1 geneGenomic DNAInactive X chromosomeDimer formationCyclobutane pyrimidine dimer formationTumor suppressor genePyrimidine dimer formationConstitutive methylationCytosine methylationMethylated cytosineUnmethylated cytosinesSuppressor geneP53 tumor suppressor geneGenesMethylationCPD formationChromosomesCytosineDNAMutationsSunlight-induced mutationsDipyrimidine sitesPGK1
1986
The C-C (6-4) UV photoproduct is mutagenic in Escherichia coli.
Glickman BW, Schaaper RM, Haseltine WA, Dunn RL, Brash DE. The C-C (6-4) UV photoproduct is mutagenic in Escherichia coli. Proceedings Of The National Academy Of Sciences Of The United States Of America 1986, 83: 6945-6949. PMID: 3529093, PMCID: PMC386627, DOI: 10.1073/pnas.83.18.6945.Peer-Reviewed Original Research
1982
New Approaches to DNA Damage and Repair: The Ultraviolet Light Example
Haseltine W, Gordon L, Lindan C, Lippke J, Brash D, Lo K, Royer-Pokora B. New Approaches to DNA Damage and Repair: The Ultraviolet Light Example. 1982, 20: 315-332. PMID: 7115270, DOI: 10.1007/978-1-4613-3476-7_21.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements