2006
Co-Opting Macrophage Traits in Cancer Progression: A Consequence of Tumor Cell Fusion?
Pawelek J, Chakraborty A, Lazova R, Yilmaz Y, Cooper D, Brash D, Handerson T. Co-Opting Macrophage Traits in Cancer Progression: A Consequence of Tumor Cell Fusion? Contributions To Microbiology 2006, 13: 138-155. PMID: 16627963, DOI: 10.1159/000092970.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsMeSH KeywordsBone Marrow NeoplasmsBreast NeoplasmsCell FusionDisease ProgressionHumansHybrid CellsMacrophagesMelanomaNeoplasmsConceptsCell fusionHuman cancersMacrophage traitsWide diversityCancer cellsTumor-associated macrophagesTumor cell fusionsBranched oligosaccharidesMultidrug resistance proteinN-glycansCancer progressionTumor initiationResistance proteinStroma productionTraitsComplex diseasesMultiple rolesCommon traitsHigh expressionGrowth factorNumerous animal tumor modelsImmune evasionDiversityMutagenic actionMost cancers
1993
Local recurrence versus new primary: Clinical analysis of 82 breast relapses and potential applications for genetic fingerprinting
Haffty B, Carter D, Flynn S, Fischer D, Brash D, Simons J, Ziegler A, Fischer J. Local recurrence versus new primary: Clinical analysis of 82 breast relapses and potential applications for genetic fingerprinting. International Journal Of Radiation Oncology • Biology • Physics 1993, 27: 575-583. PMID: 8226151, DOI: 10.1016/0360-3016(93)90382-6.Peer-Reviewed Original ResearchConceptsNew primary tumorsBreast relapsePrimary tumorTrue recurrenceNew primaryConservative surgeryLocal recurrencePathological criteriaRadiation therapyOriginal tumorSurvival rateClinical pathological analysisSecond primary tumorsShorter median timeTrue local recurrenceSignificant prognostic implicationsDNA flow cytometryLocal relapseMedian timePrognostic implicationsResidual diseaseTumor bedPathological analysisRelapseTherapeutic implications