2014
Enhancing the detection of barcoded reads in high throughput DNA sequencing data by controlling the false discovery rate
Buschmann T, Zhang R, Brash DE, Bystrykh LV. Enhancing the detection of barcoded reads in high throughput DNA sequencing data by controlling the false discovery rate. BMC Bioinformatics 2014, 15: 264. PMID: 25099007, PMCID: PMC4133078, DOI: 10.1186/1471-2105-15-264.Peer-Reviewed Original ResearchCommon Contaminants in Next-Generation Sequencing That Hinder Discovery of Low-Abundance Microbes
Laurence M, Hatzis C, Brash DE. Common Contaminants in Next-Generation Sequencing That Hinder Discovery of Low-Abundance Microbes. PLOS ONE 2014, 9: e97876. PMID: 24837716, PMCID: PMC4023998, DOI: 10.1371/journal.pone.0097876.Peer-Reviewed Original ResearchConceptsLow-abundance microbesNCBI genome databaseHigh-throughput sequencingShotgun DNA librariesUnbiased high-throughput sequencingNovel microbesGenome databaseDNA libraryNext-generation sequencingComplete genomeGenome ProjectKnown sequencesSequencing runMicrobesSequencing applicationsGenomeCommon contaminantsSequencingLaboratory contaminantsClinical specimensGenusNCBISpeciesDiversityReads
2012
Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma
Krauthammer M, Kong Y, Ha BH, Evans P, Bacchiocchi A, McCusker J, Cheng E, Davis MJ, Goh G, Choi M, Ariyan S, Narayan D, Dutton-Regester K, Capatana A, Holman EC, Bosenberg M, Sznol M, Kluger HM, Brash DE, Stern DF, Materin MA, Lo RS, Mane S, Ma S, Kidd KK, Hayward NK, Lifton RP, Schlessinger J, Boggon TJ, Halaban R. Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma. Nature Genetics 2012, 44: 1006-1014. PMID: 22842228, PMCID: PMC3432702, DOI: 10.1038/ng.2359.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overCase-Control StudiesDNA Mutational AnalysisExomeFemaleGene FrequencyGenetic Predisposition to DiseaseHumansMaleMelanomaMiddle AgedModels, MolecularMutationProto-Oncogene Proteins B-rafProto-Oncogene Proteins p21(ras)Rac1 GTP-Binding ProteinSequence Analysis, DNASkin NeoplasmsUveal NeoplasmsConceptsSun-exposed melanomas
2004
Donor DNA in a renal cell carcinoma metastasis from a bone marrow transplant recipient
Chakraborty A, Lazova R, Davies S, Bäckvall H, Ponten F, Brash D, Pawelek J. Donor DNA in a renal cell carcinoma metastasis from a bone marrow transplant recipient. Bone Marrow Transplantation 2004, 34: 183-186. PMID: 15195072, DOI: 10.1038/sj.bmt.1704547.Peer-Reviewed Original Research