1998
Skin precancer.
Brash DE, Pontén J. Skin precancer. Cancer Surveys 1998, 32: 69-113. PMID: 10489624.ChaptersConceptsTP53 mutationsClonal expansionCell carcinomaHair follicle originHigh-risk papillomasRegression of dysplasiaTP53 mutant clonesSquamous cell carcinomaBasal cell carcinomaRegression of melanomaCell of originPrecancerous eventsBCC tumorsMelanoma cell linesGenetics of melanomaPrecancerous lesionsRelative riskFamilial predispositionSuch lesionsImmunosuppressant drugsDysplastic naeviNormal skinPrecancerChemotherapeutic agentsMelanoma
1996
Sunlight and sunburn in human skin cancer: p53, apoptosis, and tumor promotion.
Brash DE, Ziegler A, Jonason AS, Simon JA, Kunala S, Leffell DJ. Sunlight and sunburn in human skin cancer: p53, apoptosis, and tumor promotion. Journal Of Investigative Dermatology Symposium Proceedings 1996, 1: 136-42. PMID: 9627707.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsSquamous cell carcinomaCell carcinomaActinic keratosisBasal cell carcinomaHuman skin cancerP53 tumor suppressor geneP53-mutated cellsSunburn cellsApoptotic keratinocytesSkin cancerP53 mutationsNormal skinTumor initiatorTumor promotionFunction of p53Cellular proofreadingTumor suppressor geneCarcinomaMouse skinClonal expansionP53 geneCarcinogenic DNA lesionsP53 allelePrecancerous cellsSunlight exposure