2006
Co-Opting Macrophage Traits in Cancer Progression: A Consequence of Tumor Cell Fusion?
Pawelek J, Chakraborty A, Lazova R, Yilmaz Y, Cooper D, Brash D, Handerson T. Co-Opting Macrophage Traits in Cancer Progression: A Consequence of Tumor Cell Fusion? Contributions To Microbiology 2006, 13: 138-155. PMID: 16627963, DOI: 10.1159/000092970.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsCell fusionHuman cancersMacrophage traitsWide diversityCancer cellsTumor-associated macrophagesTumor cell fusionsBranched oligosaccharidesMultidrug resistance proteinN-glycansCancer progressionTumor initiationResistance proteinStroma productionTraitsComplex diseasesMultiple rolesCommon traitsHigh expressionGrowth factorNumerous animal tumor modelsImmune evasionDiversityMutagenic actionMost cancers
1991
A role for sunlight in skin cancer: UV-induced p53 mutations in squamous cell carcinoma.
Brash DE, Rudolph JA, Simon JA, Lin A, McKenna GJ, Baden HP, Halperin AJ, Pontén J. A role for sunlight in skin cancer: UV-induced p53 mutations in squamous cell carcinoma. Proceedings Of The National Academy Of Sciences Of The United States Of America 1991, 88: 10124-10128. PMID: 1946433, PMCID: PMC52880, DOI: 10.1073/pnas.88.22.10124.Peer-Reviewed Original ResearchConceptsSquamous cell carcinomaCell carcinomaP53 mutationsMajor epidemiologic risk factorsUV-induced p53 mutationsInvasive squamous cell carcinomaEpidemiologic risk factorsUV-specific mutationsP53 tumor suppressor geneInternal malignancySwedish patientsRisk factorsSkin cancerTumor progressionTT double-base changesTumor suppressor geneCarcinomaHuman cancersCancerDipyrimidine sitesSuppressor geneT substitutionSkinMutationsPatients