2014
Common Contaminants in Next-Generation Sequencing That Hinder Discovery of Low-Abundance Microbes
Laurence M, Hatzis C, Brash DE. Common Contaminants in Next-Generation Sequencing That Hinder Discovery of Low-Abundance Microbes. PLOS ONE 2014, 9: e97876. PMID: 24837716, PMCID: PMC4023998, DOI: 10.1371/journal.pone.0097876.Peer-Reviewed Original ResearchConceptsLow-abundance microbesNCBI genome databaseHigh-throughput sequencingShotgun DNA librariesUnbiased high-throughput sequencingNovel microbesGenome databaseDNA libraryNext-generation sequencingComplete genomeGenome ProjectKnown sequencesSequencing runMicrobesSequencing applicationsGenomeCommon contaminantsSequencingLaboratory contaminantsClinical specimensGenusNCBISpeciesDiversityReads
2006
Co-Opting Macrophage Traits in Cancer Progression: A Consequence of Tumor Cell Fusion?
Pawelek J, Chakraborty A, Lazova R, Yilmaz Y, Cooper D, Brash D, Handerson T. Co-Opting Macrophage Traits in Cancer Progression: A Consequence of Tumor Cell Fusion? Contributions To Microbiology 2006, 13: 138-155. PMID: 16627963, DOI: 10.1159/000092970.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsCell fusionHuman cancersMacrophage traitsWide diversityCancer cellsTumor-associated macrophagesTumor cell fusionsBranched oligosaccharidesMultidrug resistance proteinN-glycansCancer progressionTumor initiationResistance proteinStroma productionTraitsComplex diseasesMultiple rolesCommon traitsHigh expressionGrowth factorNumerous animal tumor modelsImmune evasionDiversityMutagenic actionMost cancers