2016
Prevalence and Clinical, Endoscopic, and Pathological Features of Duodenitis in Children
Alper A, Hardee S, Rojas‐Velasquez D, Escalera S, Morotti RA, Pashankar DS. Prevalence and Clinical, Endoscopic, and Pathological Features of Duodenitis in Children. Journal Of Pediatric Gastroenterology And Nutrition 2016, 62: 314-316. PMID: 26252915, PMCID: PMC4724230, DOI: 10.1097/mpg.0000000000000942.Peer-Reviewed Original ResearchConceptsAssociated gastritisEndoscopic appearancePathological featuresCeliac diseaseClinical diagnosisDiagnosis of duodenitisPositive celiac serologyInflammatory bowel diseaseHelicobacter pylori infectionPatient's clinical diagnosisCeliac serologyAbdominal painUpper endoscopyVillous changesBowel diseaseCommon indicationUlcerative colitisCommon etiologyCrohn's diseasePylori infectionPathology reportsDuodenitisCommon causeEndoscopic dataLarge cohort
2014
Histopathology of Duodenal Mucosal Lesions in Pediatric Patients with Inflammatory Bowel Disease: Statistical Analysis to Identify Distinctive Features
Hardee S, Alper A, Pashankar DS, Morotti RA. Histopathology of Duodenal Mucosal Lesions in Pediatric Patients with Inflammatory Bowel Disease: Statistical Analysis to Identify Distinctive Features. Pediatric And Developmental Pathology 2014, 17: 450-454. PMID: 25207874, DOI: 10.2350/14-07-1529-oa.1.Peer-Reviewed Original ResearchConceptsUpper gastrointestinal tractVillous bluntingIntraepithelial lymphocytesPediatric patientsDuodenal lesionsDifferent etiopathogenesisUlcerative colitisCrohn's diseaseInflammatory bowel disease patientsCases of duodenitisDuodenal mucosal lesionsBowel disease patientsInflammatory bowel diseasePresence of granulomasAge-matched controlsLamina propria eosinophilsKruskal-Wallis testingCeliac groupDuodenal pathologyDuodenitis casesAssociated gastritisBowel diseaseCrypt hyperplasiaMucosal lesionsPediatric population
2001
Effect of Long-term Omeprazole Treatment on Antral G and D Cells in Children
Pashankar D, Israel D, Jevon G, Buchan A. Effect of Long-term Omeprazole Treatment on Antral G and D Cells in Children. Journal Of Pediatric Gastroenterology And Nutrition 2001, 33: 537-542. PMID: 11740225, DOI: 10.1097/00005176-200111000-00005.Peer-Reviewed Original ResearchConceptsLong-term omeprazole therapyD cell numbersAge-matched control groupG-cell numberOmeprazole therapyControl groupD cellsEndoscopic antral biopsy specimensAge groupsLong-term omeprazole treatmentErosive reflux esophagitisAntral biopsy specimensEffect of omeprazoleSignificant increaseDifferent age groupsReflux esophagitisGastrin secretionOmeprazole administrationBiopsy specimensHealthy childrenOmeprazole treatmentParacrine mannerOmeprazoleAntral glandsTherapyEfficacy and optimal dose of daily polyethylene glycol 3350 for treatment of constipation and encopresis in children
Pashankar D, Bishop W. Efficacy and optimal dose of daily polyethylene glycol 3350 for treatment of constipation and encopresis in children. The Journal Of Pediatrics 2001, 139: 428-432. PMID: 11562624, DOI: 10.1067/mpd.2001.117002.Peer-Reviewed Original ResearchConceptsChronic constipationStool frequencyStool consistencyOptimal dosePolyethylene glycol 3350Weekly stool frequencyTreatment of constipationMean effective doseFisher's exact testSignificant adverse effectsStudent's t-testFecal retentionSoft stoolDaily administrationInitial doseMean doseConstipationExact testEffective doseDoseAdverse effectsT-testChildrenTreatmentEfficacyOmeprazole Maintenance Therapy for Gastroesophageal Reflux Disease After Failure of Fundoplication
Pashankar D, Blair G, Israel D. Omeprazole Maintenance Therapy for Gastroesophageal Reflux Disease After Failure of Fundoplication. Journal Of Pediatric Gastroenterology And Nutrition 2001, 32: 145-149. PMID: 11321383, DOI: 10.1097/00005176-200102000-00010.Peer-Reviewed Original ResearchConceptsSymptoms of GERGastroesophageal refluxGastroesophageal reflux diseaseReflux diseaseRecurrence of GERFailure of fundoplicationGrade II esophagitisLong-term omeprazoleOmeprazole maintenance therapySeverity of esophagitisClinical adverse effectsSevere gastroesophageal refluxSubsequent surgical interventionLong-term drugsBenign gastric polypsMaintenance therapyPeptic strictureEsophageal dilatationFurther surgeryHiatal herniaTherapeutic challengeSurgical interventionGastric polypsMean ageClinical assessment
1999
Vitiligo and Crohn's disease in children.
Pashankar D, Prendiville J, Israel D. Vitiligo and Crohn's disease in children. Journal Of Pediatric Gastroenterology And Nutrition 1999, 28: 227-9. PMID: 9932864, DOI: 10.1097/00005176-199902000-00029.Peer-Reviewed Original Research
1997
Gastrostomy in children with Crohn’s disease
PASHANKAR D, ISRAEL D. Gastrostomy in children with Crohn’s disease. Archives Of Disease In Childhood 1997, 77: 368. PMID: 9389249, PMCID: PMC1717357, DOI: 10.1136/adc.77.4.368a.Peer-Reviewed Original Research