Colorimetric detection of proteins based on target-induced activation of aptazyme
Wu D, Gao T, Lei L, Yang D, Mao X, Li G. Colorimetric detection of proteins based on target-induced activation of aptazyme. Analytica Chimica Acta 2016, 942: 68-73. PMID: 27720123, DOI: 10.1016/j.aca.2016.09.010.Peer-Reviewed Original ResearchConceptsTarget proteinsDetection of proteinsCost-effective detectionAntibody-based assaysAptazymesTarget-induced activityGold nanoparticlesConformational changesDNA linkersProteinDetection of analytesProtein assayCross-linked gold nanoparticlesSignal amplificationEconomical synthesisAssayColorimetric detection of proteinDetection limitAssay methodSignal recognitionColorimetric detectionAnalytical performanceDetection methodGrowth factorDetection of vascular endothelial growth factorOne-Step Modification of Electrode Surface for Ultrasensitive and Highly Selective Detection of Nucleic Acids with Practical Applications
Li C, Wu D, Hu X, Xiang Y, Shu Y, Li G. One-Step Modification of Electrode Surface for Ultrasensitive and Highly Selective Detection of Nucleic Acids with Practical Applications. Analytical Chemistry 2016, 88: 7583-7590. PMID: 27374134, DOI: 10.1021/acs.analchem.6b01250.Peer-Reviewed Original ResearchConceptsElectrode surfaceCapture probeAccessibility of target moleculesSingle-base discrimination abilityFunctionalized electrode surfaceTarget moleculesUnique probe designSignal probeHairpin DNAProtein repelling abilityComplex samplesRigid scaffoldsDetection of nucleic acidsOne-step modificationBinding modelElectrodeOne-stepAcid sensorsMoleculesNucleic acid sensorsProbe bindingNucleic acidsSurfaceMicro-RNAsPractical applicationsProximity ligation-induced assembly of DNAzymes for simple and cost-effective colourimetric detection of proteins with high sensitivity
Wei L, Wang X, Wu D, Li C, Yin Y, Li G. Proximity ligation-induced assembly of DNAzymes for simple and cost-effective colourimetric detection of proteins with high sensitivity. Chemical Communications 2016, 52: 5633-5636. PMID: 27032382, DOI: 10.1039/c6cc00205f.Peer-Reviewed Original Research