2009
Dynamics of α-globin locus chromatin structure and gene expression during erythroid differentiation of human CD34+ cells in culture
Mahajan MC, Karmakar S, Newburger PE, Krause DS, Weissman SM. Dynamics of α-globin locus chromatin structure and gene expression during erythroid differentiation of human CD34+ cells in culture. Experimental Hematology 2009, 37: 1143-1156.e3. PMID: 19607874, PMCID: PMC2997688, DOI: 10.1016/j.exphem.2009.07.001.Peer-Reviewed Original ResearchMeSH KeywordsAlpha-GlobinsAntigens, CD34CCCTC-Binding FactorCells, CulturedChromatin Assembly and DisassemblyEnhancer Elements, GeneticErythroid Precursor CellsErythropoiesisErythropoietinGATA1 Transcription FactorGene Expression Regulation, DevelopmentalGlycophorinsHematopoietic Cell Growth FactorsHistonesHumansInsulator ElementsNF-E2 Transcription Factor, p45 SubunitProtein BindingRepressor ProteinsRNA Polymerase IITranscription FactorsConceptsAlpha-globin lociTranscription factor recruitmentChromatin structureGATA-1Transcription factorsErythroid differentiationGene expressionFactor recruitmentPol IIQuantitative polymerase chain reaction analysisAlpha-globin gene expressionKey erythroid transcription factorsErythroid transcription factorsNF-E2Chromatin immunoprecipitation-quantitative polymerase chain reaction analysisAlpha-globin genesUpstream activator sitesBeta-like genesPolymerase chain reaction analysisChain reaction analysisStages of erythropoiesisGlobin promoterDifferent differentiation stagesFactor CTCFHistone modifications
1997
Gotta find GATA a friend
Krause D, Perkins A. Gotta find GATA a friend. Nature Medicine 1997, 3: 960-961. PMID: 9288719, DOI: 10.1038/nm0997-960.Commentaries, Editorials and Letters