2024
Intracellular calcium links milk stasis to lysosome-dependent cell death during early mammary gland involution
Jeong J, Lee J, Talaia G, Kim W, Song J, Hong J, Yoo K, Gonzalez D, Athonvarangkul D, Shin J, Dann P, Haberman A, Kim L, Ferguson S, Choi J, Wysolmerski J. Intracellular calcium links milk stasis to lysosome-dependent cell death during early mammary gland involution. Cellular And Molecular Life Sciences 2024, 81: 29. PMID: 38212474, PMCID: PMC10784359, DOI: 10.1007/s00018-023-05044-8.Peer-Reviewed Original Research
2015
Autophagy in the CNS and Periphery Coordinate Lipophagy and Lipolysis in the Brown Adipose Tissue and Liver
Martinez-Lopez N, Garcia-Macia M, Sahu S, Athonvarangkul D, Liebling E, Merlo P, Cecconi F, Schwartz GJ, Singh R. Autophagy in the CNS and Periphery Coordinate Lipophagy and Lipolysis in the Brown Adipose Tissue and Liver. Cell Metabolism 2015, 23: 113-127. PMID: 26698918, PMCID: PMC4715637, DOI: 10.1016/j.cmet.2015.10.008.Peer-Reviewed Original ResearchMeSH KeywordsAdipocytes, BrownAdipose Tissue, BrownAmino Acid SequenceAnimalsAutophagyCold TemperatureFemaleHypothalamusLipaseLipid DropletsLipolysisLiverLysosomesMaleMice, Inbred C57BLMice, TransgenicMicrotubule-Associated ProteinsMolecular Sequence DataNeuronsOxygen ConsumptionPro-OpiomelanocortinConceptsBrown adipose tissuePOMC neuronsLipid utilizationPeripheral tissuesAdipose tissueProopiomelanocortin neuronsInter-organ communicationCentral autophagyCold-induced activationATGLAutophagosome marker LC3LipolysisNeuronsTargeted activationLipase ATGLLipophagyIntegrative physiologyTissueMiceLiverAutophagyAutophagy proteinsCytosolic lipasesCold inducesActivation