2000
Molecular Determinants of Hair Cell Phenotypic Heterogeneity—Differential Expression of K Channel Genes
Navaratnam D, Oberholtzer J. Molecular Determinants of Hair Cell Phenotypic Heterogeneity—Differential Expression of K Channel Genes. 2000, 55-68. DOI: 10.1007/978-1-4615-4223-0_4.Peer-Reviewed Original ResearchChannel genesGene expressionAuditory receptor epitheliumAdditional gene productsK channel genesBK channel variantsLevel of transcriptionHair cellsPotassium channel genesRNA processingAlternative splicingSingle geneGene productsReceptor hair cellsReceptor epitheliumExpression patternsComplex patternsGenesMolecular determinantsChannel variantsLarge familyChick basilar papillaPhenotypic heterogeneityBasilar papillaChannel isoforms
1995
Permeation Properties and Differential Expression across the Auditory Receptor Epithelium of an Inward Rectifier K+ Channel Cloned from the Chick Inner Ear *
Navaratnam D, Escobar L, Covarrubias M, Oberholtzer J. Permeation Properties and Differential Expression across the Auditory Receptor Epithelium of an Inward Rectifier K+ Channel Cloned from the Chick Inner Ear *. Journal Of Biological Chemistry 1995, 270: 19238-19245. PMID: 7642595, DOI: 10.1074/jbc.270.33.19238.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid SequenceAnimalsBariumBase SequenceBasilar MembraneChickensCloning, MolecularDNA, ComplementaryEpitheliumEvoked PotentialsGene Expression RegulationGlutamic AcidHair Cells, AuditoryMolecular Sequence DataPotassium Channel BlockersPotassium ChannelsPotassium Channels, Inwardly RectifyingSequence Homology, Amino AcidXenopusConceptsAuditory receptor epitheliumDifferential expressionSingle-channel conductanceExcellent model systemSite-directed mutagenesisPutative pore regionIon channel genesInward rectifier potassium channelChick inner earCochlear sensory epitheliumReceptor epitheliumChick cochlear hair cellsChannel genesPrimary structureCochlear hair cellsNative channelsRectifier potassium channelSensory epitheliumExternal vestibulePore regionModel systemHair cellsPotassium channelsExpressionInward rectifier potassium current