2020
Aging protects rat cortical slices against to oxygen-glucose deprivation induced damage
Gul Z, Demircan C, Bagdas D, Buyukuysal RL. Aging protects rat cortical slices against to oxygen-glucose deprivation induced damage. International Journal Of Neuroscience 2020, 130: 1183-1191. PMID: 32064981, DOI: 10.1080/00207454.2020.1730830.Peer-Reviewed Original ResearchConceptsOxygen-glucose deprivationCortical slicesRat cortical slicesMale Sprague-DawleyAged male ratsOGD mediumS100B levelsLactate dehydrogenase leakageCerebral cortexControl conditionYoung slicesMale ratsSprague-DawleyAged animalsBrain regionsBrain tissueReoxygenationMore increaseStaining intensityDehydrogenase leakagePossible involvementMinutes incubationRatsPresent studySimilar decline
2016
Protective Effects of Chlorogenic Acid and its Metabolites on Hydrogen Peroxide-Induced Alterations in Rat Brain Slices: A Comparative Study with Resveratrol
Gul Z, Demircan C, Bagdas D, Buyukuysal R. Protective Effects of Chlorogenic Acid and its Metabolites on Hydrogen Peroxide-Induced Alterations in Rat Brain Slices: A Comparative Study with Resveratrol. Neurochemical Research 2016, 41: 2075-2085. PMID: 27161374, DOI: 10.1007/s11064-016-1919-8.Peer-Reviewed Original ResearchConceptsOxidative stress parametersCortical slicesRat brain slicesRat cortical slicesStress parametersChlorogenic acidChloride stainingProtective effectBrain slicesOxidative stressQuinic acidResveratrolNatural phenolic compoundsMain metaboliteMalondialdehydeCaffeic acidROS levelsIncubation mediumPhenolic compoundsAlterationsIC50 valuesPresent studyStainingΜM H2O2Oxygen species