2024
In-Hospital Delirium and Disability and Cognitive Impairment After COVID-19 Hospitalization
Kaushik R, McAvay G, Murphy T, Acampora D, Araujo K, Charpentier P, Chattopadhyay S, Geda M, Gill T, Kaminski T, Lee S, Li J, Cohen A, Hajduk A, Ferrante L. In-Hospital Delirium and Disability and Cognitive Impairment After COVID-19 Hospitalization. JAMA Network Open 2024, 7: e2419640. PMID: 38954414, PMCID: PMC11220565, DOI: 10.1001/jamanetworkopen.2024.19640.Peer-Reviewed Original ResearchConceptsIn-hospital deliriumChart-Based Delirium Identification InstrumentOlder adultsFunctional disabilityCOVID-19 hospitalizationCognitive impairmentCohort studyAssociated with increased functional disabilityHospitalized older adultsIncreased functional disabilityAssociation of deliriumPostdischarge follow-upRisk of deliriumTertiary care systemFollow-upPresence of cognitive impairmentProspective cohort studyLogistic regression modelsOlder survivorsCare systemIncreasing cognitive impairmentMain OutcomesCOVID-19Hospital dischargePrimary outcome
2003
The effects of a targeted multicomponent delirium intervention on postdischarge outcomes for hospitalized older adults
Bogardus ST, Desai MM, Williams CS, Leo-Summers L, Acampora D, Inouye SK. The effects of a targeted multicomponent delirium intervention on postdischarge outcomes for hospitalized older adults. The American Journal Of Medicine 2003, 114: 383-390. PMID: 12714128, DOI: 10.1016/s0002-9343(02)01569-3.Peer-Reviewed Original ResearchConceptsSelf-rated healthFunctional statusIntervention groupMulticomponent interventionBetter functional statusHigh-risk patientsGood self-rated healthHospital-based interventionsHospitalized older adultsHealth care utilizationHigh-risk subgroupsHome health visitsOutcomes 6 monthsNursing home placementAcademic medical centerDelirium interventionPostdischarge outcomesHospital dischargeHealth visitsCare utilizationRisk factorsMedical CenterControl groupCognitive statusBeneficial effects
2001
Multicomponent Targeted Intervention to Prevent Delirium in Hospitalized Older Patients
Rizzo J, Bogardus S, Leo-Summers L, Williams C, Acampora D, Inouye S. Multicomponent Targeted Intervention to Prevent Delirium in Hospitalized Older Patients. Medical Care 2001, 39: 740-752. PMID: 11458138, DOI: 10.1097/00005650-200107000-00010.Peer-Reviewed Original ResearchConceptsHospitalized older personsOlder personsIntermediate riskRisk groupsHigh riskRisk factor intervention strategyCost-effective treatment optionHospitalized Older PatientsIntermediate-risk cohortPrevention of deliriumUsual hospital careIntermediate-risk groupOverall health care costsAcute confusional stateEffective treatment optionHigh-risk groupHealth care costsDelirium preventionPrevent DeliriumUsual careHospital daysOlder PatientsHospitalized patientsConfusional stateRisk cohort
1999
A Multicomponent Intervention to Prevent Delirium in Hospitalized Older Patients
Inouye S, Bogardus S, Charpentier P, Leo-Summers L, Acampora D, Holford T, Cooney L. A Multicomponent Intervention to Prevent Delirium in Hospitalized Older Patients. New England Journal Of Medicine 1999, 340: 669-676. PMID: 10053175, DOI: 10.1056/nejm199903043400901.Peer-Reviewed Original ResearchConceptsSeverity of deliriumRisk factorsCognitive impairmentRecurrence rateIntervention groupRisk factor intervention strategyHearing impairmentVisual impairmentHospitalized Older PatientsPatients 70 yearsPrevention of deliriumUsual care unitsUsual care groupGeneral medicine serviceEffective treatment strategiesDuration of episodesPrevent DeliriumOlder patientsRate of usePrimary outcomeSleep medicationPoor outcomePrimary preventionPatient's deliriumTeaching hospital