2016
Appendectomy does not decrease the risk of future colectomy in UC: results from a large cohort and meta-analysis
Parian A, Limketkai B, Koh J, Brant SR, Bitton A, Cho JH, Duerr RH, McGovern DP, Proctor DD, Regueiro MD, Rioux JD, Schumm P, Taylor KD, Silverberg MS, Steinhart AH, Hernaez R, Lazarev M. Appendectomy does not decrease the risk of future colectomy in UC: results from a large cohort and meta-analysis. Gut 2016, 66: 1390. PMID: 27196594, PMCID: PMC5065377, DOI: 10.1136/gutjnl-2016-311550.Peer-Reviewed Original ResearchConceptsUC diagnosisDisease courseImpact of appendectomyRisk of colectomyTiming of appendectomyIndependent risk factorMilder disease courseSeverity of diseaseDevelopment of UCColectomy rateFuture colectomyEarly appendectomyClinical courseMultivariable analysisRisk factorsAppendectomyColectomyLarge cohortHigh riskPatientsDiagnosisConsortium databaseNational InstituteRiskUC
2013
The Influence of Depression on Quality of Life in Patients with Inflammatory Bowel Disease
Zhang CK, Hewett J, Hemming J, Grant T, Zhao H, Abraham C, Oikonomou I, Kanakia M, Cho JH, Proctor DD. The Influence of Depression on Quality of Life in Patients with Inflammatory Bowel Disease. Inflammatory Bowel Diseases 2013, 19: 1732-1739. PMID: 23669400, PMCID: PMC4623582, DOI: 10.1097/mib.0b013e318281f395.Peer-Reviewed Original ResearchConceptsInflammatory bowel diseaseDisease activity indexHR-QOLCrohn's diseaseUlcerative colitisDisease activityBowel diseaseQuality of lifeActivity indexShort Inflammatory Bowel Disease QuestionnaireDepression InventoryInflammatory bowel disease practiceCrohn's Disease Activity IndexInflammatory Bowel Disease QuestionnairePatients' HR-QOLSeo activity indexBowel Disease QuestionnaireHealth-related qualityPoorer HR-QOLChronic inflammatory disordersPrevalence of depressionBeck Depression Inventory-IIDiagnosis of depressionCross-sectional studyImportance of depression
2011
Prospective Evaluation of Acute Graft-Versus-Host Disease
Aslanian H, Chander B, Robert M, Cooper D, Proctor D, Seropian S, Jain D. Prospective Evaluation of Acute Graft-Versus-Host Disease. Digestive Diseases And Sciences 2011, 57: 720-725. PMID: 22011927, DOI: 10.1007/s10620-011-1938-x.Peer-Reviewed Original ResearchConceptsAcute GVHDHost diseaseLower endoscopyRectal biopsyDiagnostic yieldGastrointestinal tractAllogeneic bone marrow transplantationAcute Graft-VersusCases of GVHDLower gastrointestinal involvementOptimal endoscopic approachDiagnosis of GVHDNon-specific symptomsStem cell transplantationBone marrow transplantationUpper gastrointestinal tractLower gastrointestinal tractUpper intestinal tractMajority of casesColonic GVHDGastrointestinal GVHDGastrointestinal involvementGraft-VersusGVHD casesIntestinal GVHD
2009
Phenotypic and Genotypic Characteristics of Inflammatory Bowel Disease in French Canadians: Comparison With a Large North American Repository
Elkadri A, Bitton A, Cohen A, Griffiths A, Deslandres C, Proctor D, McGovern D, Langelier D, Bernard E, Torres E, Wild G, Nguyen G, Jobin G, Aumais G, Steinhart H, Rioux J, Cho J, Bhat M, Silverberg M, Regueiro M, Goyette P, Pare P, Lahaie R, Duerr R, Brant S, Dassopoulos T. Phenotypic and Genotypic Characteristics of Inflammatory Bowel Disease in French Canadians: Comparison With a Large North American Repository. The American Journal Of Gastroenterology 2009, 104: 2233. PMID: 19513023, PMCID: PMC2742627, DOI: 10.1038/ajg.2009.267.Peer-Reviewed Original ResearchConceptsInflammatory bowel diseaseCrohn's diseaseBowel diseaseUlcerative colitisSingle nucleotide polymorphismsManagement of IBDCaucasian IBD populationsSmall bowel diseaseFrench-Canadian patientsExtraintestinal manifestationsCurrent smokersFormer smokersIBD phenotypeIBD populationCD patientsSmoking statusIncreased prevalenceKidney diseaseSurgical historyCaucasian patientsDisease behaviorFamily historyPatientsAnatomical locationDisease