2024
Central and peripheral physiological responses to decision making in hoarding disorder
Levy H, Naples A, Collett S, McPartland J, Tolin D. Central and peripheral physiological responses to decision making in hoarding disorder. International Journal Of Psychophysiology 2024, 205: 112437. PMID: 39265723, PMCID: PMC11502253, DOI: 10.1016/j.ijpsycho.2024.112437.Peer-Reviewed Original ResearchError-related negativityHoarding disorderControl participantsAlpha asymmetryPsychophysiological responsesIncreased frontal negativityGo/No-Go taskHealthy control participantsDecision-making taskPeripheral nervous system activityResponse to decisionsAnxiety disordersFrontal negativityNeurobiological modelsGo taskNeutral taskPsychiatric diagnosisExcessive clutterPsychophysiological measuresPersonal possessionsExaggerated activationDisordersNull resultsNervous system activityTaskThe relationship between momentary experiential avoidance and anxiety symptoms
Sain K, Lord K, Knowles K, Everhardt K, Tolin D. The relationship between momentary experiential avoidance and anxiety symptoms. Anxiety Stress & Coping 2024, ahead-of-print: 1-13. PMID: 39104256, DOI: 10.1080/10615806.2024.2383769.Peer-Reviewed Original ResearchEcological momentary assessmentExperiential avoidanceAnxiety-related disordersAnxiety symptomsClinical sample of participantsSample of treatment-seeking patientsAssociated with greater anxietyAnxiety-related psychopathologySocial anxiety disorderBidirectional relationshipTreatment-seeking patientsTrend-level associationsSample of participantsIn-the-momentNonclinical undergraduatesAnxiety disordersMomentary assessmentGreater anxietyPerceived stressAnxietyBaseline assessmentClinical samplesDisordersTime pointsAssessment periodReductions in Anxiety are Associated with Decreased Expressive Suppression and Increased Cognitive Reappraisal After Cognitive-Behavioral Treatment: A Naturalistic Study in Youth
Knowles K, Tolin D. Reductions in Anxiety are Associated with Decreased Expressive Suppression and Increased Cognitive Reappraisal After Cognitive-Behavioral Treatment: A Naturalistic Study in Youth. Child Psychiatry & Human Development 2024, 1-8. PMID: 38530590, DOI: 10.1007/s10578-024-01684-4.Peer-Reviewed Original ResearchCognitive-behavioral therapyObsessive-compulsive disorderCognitive reappraisalExpressive suppressionAnxious youthSessions of cognitive-behavioral therapyEmotion regulation strategy usePrimary obsessive-compulsive disorderObsessive-compulsive disorder symptomsRegulation strategy useCognitive-behavioral treatmentTreatment-seeking sampleAnxiety-related disordersEmotion regulation strategiesEmotion regulation abilitiesEmotion regulation skillsMeasures of anxietyPost-treatment anxietyAssociated with anxiety reductionAnxiety disordersCognitive-behavioralEmotion regulationBroad deficitsRegulation skillsNaturalistic studyAn investigation of the role of estradiol in fear reduction during a single session of exposure therapy
Levy H, Mullins J, Tolin D. An investigation of the role of estradiol in fear reduction during a single session of exposure therapy. Cognitive Behaviour Therapy 2024, 53: 364-376. PMID: 38299480, DOI: 10.1080/16506073.2024.2313743.Peer-Reviewed Original ResearchObsessive-compulsive disorderExposure therapyAnxiety disordersPrimary obsessive-compulsive disorderSubjective distress ratingsAnxiety specialty clinicLow estradiol groupFear extinctionSubjective distressFear reductionExposure sessionsBrief delayDistress ratingsRecall delayAnxietyTherapy researchExposure outcomesDisordersSpecialty clinicsHigher estradiolDistressPrimary diagnosisEndogenous estradiolRecallEstradiol groupSymptom distress and psychosocial functioning improve bidirectionally during cognitive-behavioral therapy for anxiety disorders
Lord K, Tolin D. Symptom distress and psychosocial functioning improve bidirectionally during cognitive-behavioral therapy for anxiety disorders. Journal Of Anxiety Disorders 2024, 103: 102843. PMID: 38310753, DOI: 10.1016/j.janxdis.2024.102843.Peer-Reviewed Original ResearchCognitive-behavioral therapyPsychosocial functioningAnxiety disordersSymptom distressEfficacy of cognitive-behavioral therapySessions of cognitive-behavioral therapyPresence of comorbid depressionIndicators of psychosocial functioningAnxiety disorder symptomsOutcome Questionnaire-45Measures of symptom distressCross-lagged analysisSocial role performanceInterpersonal problemsAnxiety symptomsDisorder symptomsComorbid depressionSymptom reductionSymptom ameliorationLow levels of severityLevels of severityAnxietyEffect sizeDistressAssociated with changes
2023
The DIAMOND-KID: Psychometric Properties of a Structured Diagnostic Interview for DSM-5 Anxiety, Mood, and Obsessive-Compulsive and Related Disorders in Children and Adolescents
Tolin D, Sain K, Davis E, Gilliam C, Hannan S, Springer K, Stubbing J, George J, Jean A, Goldblum R, Katz B, Everhardt K, Darrow S, Ohr E, Young M, Serchuk M. The DIAMOND-KID: Psychometric Properties of a Structured Diagnostic Interview for DSM-5 Anxiety, Mood, and Obsessive-Compulsive and Related Disorders in Children and Adolescents. Assessment 2023, 30: 2351-2363. PMID: 36632642, DOI: 10.1177/10731911221143994.Peer-Reviewed Original ResearchConceptsSelf-report measuresDiagnostic InterviewSemi-structured diagnostic interviewObsessive-compulsive disorderGeneralized anxiety disorderSymptoms of anxietyDSM-5 AnxietyPediatric psychiatric disordersTest-retest reliability dataDisorder childrenAdolescent versionTest-retest reliabilityObsessive-CompulsiveAnxiety disordersConvergent validitySemi-structured interviewsQuestionable rangePsychometric propertiesAnxietyMoodRelated disordersInterrater reliability dataInitial interviewParents/guardiansGroup comparisonsExposure therapy for anxiety disorders
Stanton C, Tolin D. Exposure therapy for anxiety disorders. 2023, 857-865. DOI: 10.1016/b978-0-323-91497-0.00065-5.Peer-Reviewed Original Research
2021
Hoarding Disorder
Worden B, Tolin D. Hoarding Disorder. 2021, 63-86. DOI: 10.1093/med-psych/9780190052775.003.0005.Peer-Reviewed Original ResearchLow Estradiol May Not Impede Cognitive Restructuring in Women With Anxiety Disorders.
Levy H, Jean A, Ching T, Nett A, Mullins J, Tolin D. Low Estradiol May Not Impede Cognitive Restructuring in Women With Anxiety Disorders. Journal Of Cognitive Psychotherapy 2021, 35: 212-220. PMID: 34362860, DOI: 10.1891/jcpsy-d-20-00038.Peer-Reviewed Original ResearchConceptsCognitive restructuringCognitive reappraisalAnxiety disordersCR taskExtinction-based therapiesSubjective distress ratingsPrimary anxiety disorderSkin conductance responsesLow estradiol groupFear extinctionNegative affectPsychophysiological arousalConductance responsesDistress ratingsCR outcomesCR abilityLow estradiolCR skillsExtinction processPrior researchTaskReappraisalEstradiol groupDisordersAcquisitionPsychophysiological assessment of stress reactivity and recovery in anxiety disorders
Tolin DF, Lee E, Levy HC, Das A, Mammo L, Katz BW, Diefenbach GJ. Psychophysiological assessment of stress reactivity and recovery in anxiety disorders. Journal Of Anxiety Disorders 2021, 82: 102426. PMID: 34022509, DOI: 10.1016/j.janxdis.2021.102426.Peer-Reviewed Original ResearchConceptsGeneralized anxiety disorderCognitive behavioral therapyAnxiety disordersPanic disorderStressor phaseCBT outcomeHigh-frequency heart rate variabilityFrequency heart rate variabilityPsychophysiological reactivityEnd-tidal CODSM-5 anxiety disordersSpecialty outpatient clinicsHealthy control participantsHeart rate variabilityAdult patientsOutpatient clinicRate recoveryPatientsReactivity phaseResting phaseAnxious patientsAutonomic recoveryRate variabilityControl participantsDiminished changes
2019
Inhibitory Learning for Anxiety-Related Disorders
Tolin D. Inhibitory Learning for Anxiety-Related Disorders. Cognitive And Behavioral Practice 2019, 26: 225-236. DOI: 10.1016/j.cbpra.2018.07.008.Peer-Reviewed Original Research
2018
An Evaluation of the Effectiveness of a Transdiagnostic Bibliotherapy Program for Anxiety and Related Disorders: Results From Two Studies Using a Benchmarking Approach
Wootton B, Steinman S, Czerniawski A, Norris K, Baptie C, Diefenbach G, Tolin D. An Evaluation of the Effectiveness of a Transdiagnostic Bibliotherapy Program for Anxiety and Related Disorders: Results From Two Studies Using a Benchmarking Approach. Cognitive Therapy And Research 2018, 42: 565-580. DOI: 10.1007/s10608-018-9921-x.Peer-Reviewed Original ResearchCognitive behavior therapyGroup effect sizesRelated disordersPrimary outcome measureEvidence-based treatmentsTreatment of anxietyMixed anxiety disordersEffect sizeFirst studyOpen trialOutcome measuresEffective treatmentStudy participantsAnxiety disordersDisordersBehavior therapyTreatmentPatientsSignificant reductionInterventionFollowAnxietyTrialsPreliminary supportParticipants
2017
582 Functional Connectivity Changes following Repetitive Transcranial Magnetic Stimulation (rTMS) in Individuals with Generalized Anxiety Disorder
Assaf M, Rabany L, Zertuche L, Bragdon L, Tolin D, Goethe J, Diefenbach G. 582 Functional Connectivity Changes following Repetitive Transcranial Magnetic Stimulation (rTMS) in Individuals with Generalized Anxiety Disorder. Biological Psychiatry 2017, 81: s235. DOI: 10.1016/j.biopsych.2017.02.452.Peer-Reviewed Original ResearchCognitive Control in Generalized Anxiety Disorder: Relation of Inhibition Impairments to Worry and Anxiety Severity
Hallion L, Tolin D, Assaf M, Goethe J, Diefenbach G. Cognitive Control in Generalized Anxiety Disorder: Relation of Inhibition Impairments to Worry and Anxiety Severity. Cognitive Therapy And Research 2017, 41: 610-618. DOI: 10.1007/s10608-017-9832-2.Peer-Reviewed Original ResearchGeneralized anxiety disorderAnxiety severityCognitive controlNoGo taskInhibition impairmentAnxiety disordersGo/NoGo performanceGo/NoGo taskTests of inhibitionNeurocognitive interventionsStroop performanceCognitive modelTrait worryGAD statusGAD symptomsGAD diagnosisWorse performanceQualified supportStroopTaskWorryImpairmentTheoretical modelHealthy controlsDisorders
2016
Exposure Therapy for Anxiety Disorders
Steinman S, Wootton B, Tolin D. Exposure Therapy for Anxiety Disorders. 2016, 186-191. DOI: 10.1016/b978-0-12-397045-9.00266-4.Peer-Reviewed Original Research
2015
Comorbidity in Hoarding Disorder
Frost R, Steketee G, Tolin D. Comorbidity in Hoarding Disorder. FOCUS The Journal Of Lifelong Learning In Psychiatry 2015, 13: 244-251. DOI: 10.1176/appi.focus.130218.Peer-Reviewed Original ResearchMajor depressive disorderObsessive-compulsive disorderImpulse control disordersControl disordersRates of MDDRate of OCDHD participantsHigh comorbidity ratesParticipants meeting criteriaSpecific anxiety disordersSerious methodological shortcomingsPsychiatric comorbiditySample of peopleDepressive disorderComorbidity patternsComorbidity ratesMeeting criteriaComorbiditiesDistinct disordersAnxiety disordersLarge-scale studiesDisordersHoarding DisorderInattentive ADHDCompulsive disorderDevelopment of an Anxiety Sensitivity (AS) Intervention for High-AS Individuals in Substance Use Disorders Treatment
Worden B, Davis E, Genova M, Tolin D. Development of an Anxiety Sensitivity (AS) Intervention for High-AS Individuals in Substance Use Disorders Treatment. Cognitive Therapy And Research 2015, 39: 343-355. DOI: 10.1007/s10608-014-9666-0.Peer-Reviewed Original ResearchAnxiety sensitivity interventionAnxiety sensitivitySubstance use disordersSubstance useAnxiety Sensitivity IndexCurrent open trialOutpatient SUD treatment programPercent days abstinentAnxiety subscale scoresCognitive challengingProblematic anxietyInteroceptive exposureNonclinical rangeAnxiety symptomsSUD treatment programsAnxiety disordersDepression AnxietySubjective reportsSubstance use disorder treatmentDays abstinentClinical rangeUse disorder treatmentTreatment programDisorder treatmentSubscale scores
2014
Beating a Dead Dodo Bird: Looking at Signal vs. Noise in Cognitive-Behavioral Therapy for Anxiety Disorders
Tolin D. Beating a Dead Dodo Bird: Looking at Signal vs. Noise in Cognitive-Behavioral Therapy for Anxiety Disorders. Clinical Psychology Science And Practice 2014, 21: 351-362. DOI: 10.1111/cpsp.12080.Peer-Reviewed Original Research
2012
Metacognitive Beliefs in Late-Life Generalized Anxiety Disorder
Diefenbach G, Gilliam C, Tolin D. Metacognitive Beliefs in Late-Life Generalized Anxiety Disorder. Journal Of Experimental Psychopathology 2012, 3: 768-781. DOI: 10.5127/jep.021911.Peer-Reviewed Original Research
2005
Mindfulness- and Acceptance-Based Behavior Therapy for Obsessive-Compulsive Disorder
Hannan S, Tolin D. Mindfulness- and Acceptance-Based Behavior Therapy for Obsessive-Compulsive Disorder. Series In Anxiety And Related Disorders 2005, 271-299. DOI: 10.1007/0-387-25989-9_11.Peer-Reviewed Original Research