2016
Direct vitamin D3 actions on rhesus macaque follicles in three-dimensional culture: assessment of follicle survival, growth, steroid, and antimüllerian hormone production
Xu J, Hennebold JD, Seifer DB. Direct vitamin D3 actions on rhesus macaque follicles in three-dimensional culture: assessment of follicle survival, growth, steroid, and antimüllerian hormone production. Fertility And Sterility 2016, 106: 1815-1820.e1. PMID: 27678030, PMCID: PMC5136302, DOI: 10.1016/j.fertnstert.2016.08.037.Peer-Reviewed Original ResearchConceptsVitamin D3Follicle survivalPreantral follicle survivalAntral folliclesWeek 5High-dose vitamin D3Direct actionAntimüllerian hormone concentrationsAntral follicle diameterPrimate follicular developmentVitamin D3 actionAntral follicle growthDihydroxy vitamin D3Rhesus monkey ovariesSecondary preantral folliclesFemale rhesus macaquesMacaque folliclesPrimate follicleD3 actionAMH concentrationsNational Primate Research CenterAMH productionPrimate Research CenterFollicle diameterMAIN OUTCOME
2005
Metformin reduces serum müllerian-inhibiting substance levels in women with polycystic ovary syndrome after protracted treatment
Fleming R, Harborne L, MacLaughlin DT, Ling D, Norman J, Sattar N, Seifer DB. Metformin reduces serum müllerian-inhibiting substance levels in women with polycystic ovary syndrome after protracted treatment. Fertility And Sterility 2005, 83: 130-136. PMID: 15652898, DOI: 10.1016/j.fertnstert.2004.05.098.Peer-Reviewed Original ResearchConceptsPolycystic ovary syndromeDoses of metforminObese womenOvary syndromeMenstrual frequencyMetformin treatmentHormone changesReproductive hormone changesMonths of treatmentCohort of folliclesUniversity Teaching HospitalOvarian responseOvarian functionTeaching hospitalMAIN OUTCOMEMIS concentrationsProspective treatmentSubstance levelsMetforminMonthsWomenAssessment periodTreatmentSyndromeDoses