2000
Ionic Mechanisms Underlying Repetitive High-Frequency Burst Firing in Supragranular Cortical Neurons
Brumberg J, Nowak L, McCormick D. Ionic Mechanisms Underlying Repetitive High-Frequency Burst Firing in Supragranular Cortical Neurons. Journal Of Neuroscience 2000, 20: 4829-4843. PMID: 10864940, PMCID: PMC6772270, DOI: 10.1523/jneurosci.20-13-04829.2000.Peer-Reviewed Original ResearchConceptsLayer II/III pyramidal neuronsHigh-frequency burst dischargesAction potential generationAction potentialsPyramidal neuronsCortical neuronsBurst dischargesHigh-frequency burst firingVisual cortical slicesAction potential burstsFirst action potentialBurst-firing modeHigh-frequency burstsPotential generationIonic mechanismsIntrinsic burstsCortical slicesLocal cortical networksBurst firingNeocortical neuronsIntracellular recordingsPostsynaptic neuronsATX IIQX-314Single spiking
1999
Ca2+‐Mediated Up‐Regulation of Ih in the Thalamus: How Cell‐Intrinsic Ionic Currents May Shape Network Activity
LÜTHI A, McCORMICK D. Ca2+‐Mediated Up‐Regulation of Ih in the Thalamus: How Cell‐Intrinsic Ionic Currents May Shape Network Activity. Annals Of The New York Academy Of Sciences 1999, 868: 765-769. PMID: 10414362, DOI: 10.1111/j.1749-6632.1999.tb11354.x.Peer-Reviewed Original Research
1998
Periodicity of Thalamic Synchronized Oscillations: the Role of Ca2+-Mediated Upregulation of Ih
Lüthi A, McCormick D. Periodicity of Thalamic Synchronized Oscillations: the Role of Ca2+-Mediated Upregulation of Ih. Neuron 1998, 20: 553-563. PMID: 9539128, DOI: 10.1016/s0896-6273(00)80994-0.Peer-Reviewed Original ResearchConceptsPersistent activationRefractory periodHyperpolarization-activated cation current IhNeural network oscillationsSynchronized network activityWave seizuresRole of Ca2Synchronized dischargesThalamocortical cellsThalamocortical networkElectrophysiological propertiesMediated UpregulationSpindle wavesCurrent IhConstituent neuronsNetwork oscillationsAbnormal patternsActivation curveTime courseNetwork activityUpregulationActivationCritical determinant