2006
Modulation of intracortical synaptic potentials by presynaptic somatic membrane potential
Shu Y, Hasenstaub A, Duque A, Yu Y, McCormick D. Modulation of intracortical synaptic potentials by presynaptic somatic membrane potential. Nature 2006, 441: 761-765. PMID: 16625207, DOI: 10.1038/nature04720.Peer-Reviewed Original ResearchConceptsIntracortical synaptic potentialsSomatic membrane potentialCerebral cortexMembrane potentialPostsynaptic potentialsSynaptic potentialsSynaptic activityEpileptic seizuresAction potentialsSensory stimulationNeuronal communicationMembrane potential changesNeuronal signalsRecording pointsSole formPossible alternative mechanismSeizuresCortexAxonsNeurons
2001
ON THE CELLULAR AND NETWORK BASES OF EPILEPTIC SEIZURES
McCormick D, Contreras D. ON THE CELLULAR AND NETWORK BASES OF EPILEPTIC SEIZURES. Annual Review Of Physiology 2001, 63: 815-846. PMID: 11181977, DOI: 10.1146/annurev.physiol.63.1.815.Peer-Reviewed Original ResearchConceptsCerebral cortexEpileptic seizuresSynchronized burstsRhythmic burst dischargesSpike-wave activityIntrinsic membrane propertiesForm of seizuresPeriod of hyperpolarizationLoss of balanceRecurrent excitatory connectionsEpileptic syndromesSeizure dischargesPyramidal neuronsTonic depolarizationEpileptiform activitySeizure generationBurst dischargesInhibitory neuronsInhibitory influenceInterictal spikesNormal brain rhythmsSynaptic plasticityAction potentialsSeizuresMammalian forebrain
1999
Chapter 17 Thalamic and thalamocortical mechanisms underlying 3 Hz spike-and-wave discharges
Destexhe A, McCormick D, Sejnowski T. Chapter 17 Thalamic and thalamocortical mechanisms underlying 3 Hz spike-and-wave discharges. Progress In Brain Research 1999, 121: 289-307. PMID: 10551033, DOI: 10.1016/s0079-6123(08)63080-0.Peer-Reviewed Original Research
1996
What Stops Synchronized Thalamocortical Oscillations?
Bal T, McCormick D. What Stops Synchronized Thalamocortical Oscillations? Neuron 1996, 17: 297-308. PMID: 8780653, DOI: 10.1016/s0896-6273(00)80161-0.Peer-Reviewed Original Research
1995
Thalamocortical Interactions
Huguenard J, McCormick D, Coulter D. Thalamocortical Interactions. 1995, 156-173. DOI: 10.1093/acprof:oso/9780195083309.003.0011.Peer-Reviewed Original Research
1994
From Cellular to Network Mechanisms of a Thalamic Synchronized Oscillation
Bal T, von Krosigk M, McCormick D. From Cellular to Network Mechanisms of a Thalamic Synchronized Oscillation. Research And Perspectives In Neurosciences 1994, 129-143. DOI: 10.1007/978-3-642-85148-3_8.Peer-Reviewed Original ResearchSpindle wavesDorsal lateral geniculate nucleusFerret dorsal lateral geniculate nucleusIntracellular recording techniquesLateral geniculate nucleusGeneralized epilepsyAbsence seizuresGABAA receptorsSlice preparationGeniculate nucleusPharmacological blockSynaptic networksNeural circuitsRecording techniquesCortical systemsPhysiological basisIonic conductancesEpilepsySeizuresLGNdSynchronized oscillations
1993
Cellular Mechanisms of a Synchronized Oscillation in the Thalamus
von M, Bal T, McCormick D. Cellular Mechanisms of a Synchronized Oscillation in the Thalamus. Science 1993, 261: 361-364. PMID: 8392750, DOI: 10.1126/science.8392750.Peer-Reviewed Original ResearchConceptsInhibitory postsynaptic potentialsSpindle wavesPostsynaptic potentialsAbsence seizuresRelay cellsFerret lateral geniculate nucleusRhythmic population activityGABAB inhibitory postsynaptic potentialsReceptor-mediated inhibitionSeizure-like activityLateral geniculate nucleusGABAB receptorsRebound burstsGABAB antagonistRelay neuronsPerigeniculate nucleusGeniculate nucleusPharmacological blockNeuronal activityCortical systemsCellular mechanismsPopulation activitySeizuresCellsThalamus
1992
Neurotransmitter Actions in the Thalamus and Cerebral Cortex
McCormick D. Neurotransmitter Actions in the Thalamus and Cerebral Cortex. Journal Of Clinical Neurophysiology 1992, 9: 212-223. PMID: 1350591, DOI: 10.1097/00004691-199204010-00004.Peer-Reviewed Original ResearchConceptsGamma-aminobutyric acidCerebral cortexThalamocortical activityInhibitory amino acidsSleep-wake cyclePostsynaptic actionsCortical neuronsNeurotransmitter actionEpileptic seizuresSynaptic informationTransmitter actionThalamusNorepinephrineAcetylcholineCortexNeurotransmittersSeizuresExcitabilityNeocortexHistamineExcitatoryState of activityNeuronsActivity