2003
Cellular and Network Mechanisms of Slow Oscillatory Activity (<1 Hz) and Wave Propagations in a Cortical Network Model
Compte A, Sanchez-Vives M, McCormick D, Wang X. Cellular and Network Mechanisms of Slow Oscillatory Activity (<1 Hz) and Wave Propagations in a Cortical Network Model. Journal Of Neurophysiology 2003, 89: 2707-2725. PMID: 12612051, DOI: 10.1152/jn.00845.2002.Peer-Reviewed Original ResearchConceptsSlow oscillatory activityOscillatory activityUp statesSpontaneous spike dischargeMinority of neuronsSlow-wave sleepStrong recurrent excitationSpike dischargesTonic firingCerebrospinal fluidDown statePharmacological manipulationRecurrent excitationCortical network modelSlow adaptation currentBiophysical network modelInput resistancePhysiological effectsSlow oscillationsPatchy connectionsInhibition blocksVivo dataNeuronsSingle neuron behaviorBath solution
1994
Developmental changes in electrophysiological properties of LGNd neurons during reorganization of retinogeniculate connections
Ramoa A, McCormick D. Developmental changes in electrophysiological properties of LGNd neurons during reorganization of retinogeniculate connections. Journal Of Neuroscience 1994, 14: 2089-2097. PMID: 8158259, PMCID: PMC6577110, DOI: 10.1523/jneurosci.14-04-02089.1994.Peer-Reviewed Original ResearchConceptsLGNd neuronsImmature neuronsAction potentialsElectrophysiological propertiesLittle spike frequency adaptationDependent action potentialsAction potential activityEarly postnatal lifeWhole-cell recordingsEarly postnatal developmentPatch-clamp techniqueSpike frequency adaptationHigh input resistanceDorsal LGNImmature synapsesCritical developmental periodRetinogeniculate connectionsMembrane potentialPostnatal weekIntracellular injectionPostnatal lifePostnatal developmentNeuronsInput resistanceFrequency adaptation
1987
Post‐natal development of electrophysiological properties of rat cerebral cortical pyramidal neurones.
McCormick D, Prince D. Post‐natal development of electrophysiological properties of rat cerebral cortical pyramidal neurones. The Journal Of Physiology 1987, 393: 743-762. PMID: 2895811, PMCID: PMC1192421, DOI: 10.1113/jphysiol.1987.sp016851.Peer-Reviewed Original ResearchConceptsCortical pyramidal neuronesPost-natal developmentImmature neuronesAction potentialsPyramidal neuronesCortical layer V pyramidal neuronsElectrophysiological propertiesRat sensorimotor cortical slicesLayer V pyramidal neuronsDependent action potentialsApparent input resistanceSensorimotor cortical slicesThird week postPyramidal neuronsCortical slicesIntracellular recordingsWeek postCortical neuronesNeuronesInput resistanceAdult neuronesLonger durationSpecific membrane resistanceInward rectificationAge
1985
Two types of muscarinic response to acetylcholine in mammalian cortical neurons.
McCormick D, Prince D. Two types of muscarinic response to acetylcholine in mammalian cortical neurons. Proceedings Of The National Academy Of Sciences Of The United States Of America 1985, 82: 6344-6348. PMID: 3862134, PMCID: PMC391050, DOI: 10.1073/pnas.82.18.6344.Peer-Reviewed Original ResearchConceptsGamma-aminobutyric acidInput resistanceMuscarinic responsesPyramidal neuronsPyramidal cellsInhibitory neurotransmitter gamma-aminobutyric acidNeurotransmitter gamma-aminobutyric acidShort-latency depolarizationsShort-latency inhibitionMammalian cortical neuronsNeuronal input resistanceSlow excitatory responsesApplication of acetylcholineVoltage-dependent depolarizationCholinergic inhibitionExcitatory responsesCholinergic receptorsVoltage-dependent increaseCortical slicesGABAergic interneuronsNicotinic antagonistsCholinergic agonistsCortical neuronsSlow depolarizationNeocortical neurons