2016
Real-time Tumor Oxygenation Changes After Single High-dose Radiation Therapy in Orthotopic and Subcutaneous Lung Cancer in Mice: Clinical Implication for Stereotactic Ablative Radiation Therapy Schedule Optimization
Song C, Hong BJ, Bok S, Lee CJ, Kim YE, Jeon SR, Wu HG, Lee YS, Cheon GJ, Paeng JC, Carlson DJ, Kim HJ, Ahn GO. Real-time Tumor Oxygenation Changes After Single High-dose Radiation Therapy in Orthotopic and Subcutaneous Lung Cancer in Mice: Clinical Implication for Stereotactic Ablative Radiation Therapy Schedule Optimization. International Journal Of Radiation Oncology • Biology • Physics 2016, 95: 1022-1031. PMID: 27130790, DOI: 10.1016/j.ijrobp.2016.01.064.Peer-Reviewed Original ResearchConceptsStereotactic ablative radiation therapyTumor/brain ratiosAblative radiation therapyRadiation therapyDay 0Day 6Brain ratioSingle doseVascular collapseHigh-dose irradiationDay 2Single high-dose irradiationHigh-dose radiation therapyTumor hypoxiaSyngeneic Lewis lung carcinomaHoechst 33342 perfusionTumor oxygenation changesRadiation therapy schedulesLewis lung carcinomaOrthotopic lung tumorsOptimal fractionation schedulePositron emission tomography (PET) imagingEmission Tomography ImagingTumor hypoxia levelsFluorescence-activated cell
2015
High-dose and fractionation effects in stereotactic radiation therapy: Analysis of tumor control data from 2965 patients
Shuryak I, Carlson DJ, Brown JM, Brenner DJ. High-dose and fractionation effects in stereotactic radiation therapy: Analysis of tumor control data from 2965 patients. Radiotherapy And Oncology 2015, 115: 327-334. PMID: 26058991, DOI: 10.1016/j.radonc.2015.05.013.Peer-Reviewed Original ResearchConceptsMulti-fraction stereotactic radiotherapyStereotactic radiotherapyTumoricidal mechanismsTumor controlHigh dosesSingle-dose stereotactic radiotherapySingle-fraction treatmentStereotactic radiation therapyTumor control dataBrain metastasesLung tumorsSRT patientsRadiation therapyTreatment dosesLow dosesSRT treatmentDosesLinear-quadratic modelPatientsFraction numberTreatmentLung dataLQ modelControl dataMetastasisSynthesis of [18F]FMISO in a flow-through microfluidic reactor: Development and clinical application
Zheng MQ, Collier L, Bois F, Kelada OJ, Hammond K, Ropchan J, Akula MR, Carlson DJ, Kabalka GW, Huang Y. Synthesis of [18F]FMISO in a flow-through microfluidic reactor: Development and clinical application. Nuclear Medicine And Biology 2015, 42: 578-584. PMID: 25779036, DOI: 10.1016/j.nucmedbio.2015.01.010.Peer-Reviewed Original Research
2013
Dose Escalation, Not “New Biology,” Can Account for the Efficacy of Stereotactic Body Radiation Therapy With Non-Small Cell Lung Cancer
Brown JM, Brenner DJ, Carlson DJ. Dose Escalation, Not “New Biology,” Can Account for the Efficacy of Stereotactic Body Radiation Therapy With Non-Small Cell Lung Cancer. International Journal Of Radiation Oncology • Biology • Physics 2013, 85: 1159-1160. PMID: 23517805, PMCID: PMC3608927, DOI: 10.1016/j.ijrobp.2012.11.003.Peer-Reviewed Original Research
2009
DMLC motion tracking of moving targets for intensity modulated arc therapy treatment – a feasibility study
Zimmerman J, Korreman S, Persson G, Cattell H, Svatos M, Sawant A, Venkat R, Carlson D, Keall P. DMLC motion tracking of moving targets for intensity modulated arc therapy treatment – a feasibility study. Acta Oncologica 2009, 48: 245-250. PMID: 18720056, DOI: 10.1080/02841860802266722.Peer-Reviewed Original Research