2005
Insulin auto-antigenicity in type 1 diabetes (Reply)
Hafler D, Kent S, Chen Y, Bregoli L, Clemmings S, Hering B, Kenyon N, Ricordi C. Insulin auto-antigenicity in type 1 diabetes (Reply). Nature 2005, 438: e5-e6. DOI: 10.1038/nature04424.Peer-Reviewed Original Research
1994
T cell anergy
Lasalle J, Hafler D. T cell anergy. The FASEB Journal 1994, 8: 601-608. PMID: 8005388, DOI: 10.1096/fasebj.8.9.8005388.Peer-Reviewed Original ResearchConceptsImmunologic self toleranceAutoreactive T cellsT cell anergyMHC class IIT cellsClonal anergyT cell presentationT cell clonal anergySelf antigensCell anergySelf toleranceCell presentationClass IIAutologous T cellsAbsence of costimulationHuman T cellsSecondary unresponsivenessHigh extracellular concentrationsAntigenic stimulationAntigen presentationAntigen resultsAnergyPrimary proliferationPeptide antigensAntigen