2007
Effects of Marijuana Smoking on Pulmonary Function and Respiratory Complications: A Systematic Review
Tetrault JM, Crothers K, Moore BA, Mehra R, Concato J, Fiellin DA. Effects of Marijuana Smoking on Pulmonary Function and Respiratory Complications: A Systematic Review. JAMA Internal Medicine 2007, 167: 221-228. PMID: 17296876, PMCID: PMC2720277, DOI: 10.1001/archinte.167.3.221.Peer-Reviewed Original ResearchConceptsRespiratory complicationsPulmonary functionMarijuana smokingRespiratory symptomsSystematic reviewChallenge studiesEvaluated study qualityObstructive lung diseaseAirway responsesLung diseaseEmbase databasesStudy qualityIndependent reviewersShort-term exposureSmokingComplicationsPhysiologic dataConsistent associationMarijuana administrationClinical applicabilityBronchodilationSymptomsMarijuana useAssociationOverall quality
2006
The Association Between Marijuana Smoking and Lung Cancer: A Systematic Review
Mehra R, Moore BA, Crothers K, Tetrault J, Fiellin DA. The Association Between Marijuana Smoking and Lung Cancer: A Systematic Review. JAMA Internal Medicine 2006, 166: 1359-1367. PMID: 16832000, DOI: 10.1001/archinte.166.13.1359.Peer-Reviewed Original ResearchConceptsLung cancerMarijuana smokingLung cancer risk factorsCancer risk factorsPotential adverse health outcomesPersons 18 yearsAdverse health outcomesFurther rigorous studiesEnglish-language studiesLung changesTobacco smokingTobacco smokersHistopathologic abnormalitiesHistopathologic findingsEmbase databasesPremalignant changesRisk factorsObservational studyMarijuana exposureMethodologic deficienciesTobacco useNineteen studiesSmokingTar exposureLack of adjustment