2023
URINE TOXICOLOGY PROFILES OF EMERGENCY DEPARTMENT PATIENTS WITH UNTREATED OPIOID USE DISORDER: A MULTI-SITE VIEW
Cowan E, Perrone J, Dziura J, Edelman E, Hawk K, Herring A, McCormack R, Murphy A, Phadke M, Fiellin D, D'Onofrio G. URINE TOXICOLOGY PROFILES OF EMERGENCY DEPARTMENT PATIENTS WITH UNTREATED OPIOID USE DISORDER: A MULTI-SITE VIEW. Journal Of Emergency Medicine 2023, 65: e357-e365. PMID: 37716904, PMCID: PMC10591927, DOI: 10.1016/j.jemermed.2023.06.007.Peer-Reviewed Original ResearchUrine drug screensOpioid use disorderEmergency departmentUntreated opioid use disorderAdult ED patientsOpioid overdose deathsED patientsOnly opioidCommon opioidsOverdose deathsUse disordersCommon drugsOpioidsPolysubstance useDrug useDrug screensAmphetamine-type stimulantsFentanylPatientsAddiction treatmentStimulantsParticipantsBuprenorphineMethadoneBenzodiazepinesConcordance between controlled substance receipt and post-mortem toxicology in opioid-detected overdose deaths: A statewide analysis
Howell B, Black A, Grau L, Lin H, Greene C, Lee H, Heimer R, Hawk K, D'Onofrio G, Fiellin D, Becker W. Concordance between controlled substance receipt and post-mortem toxicology in opioid-detected overdose deaths: A statewide analysis. Drug And Alcohol Dependence 2023, 244: 109788. PMID: 36738634, PMCID: PMC9975083, DOI: 10.1016/j.drugalcdep.2023.109788.Peer-Reviewed Original ResearchConceptsPost-mortem toxicologyOverdose deathsChief Medical ExaminerBenzodiazepine prescribingBenzodiazepine prescriptionsPrimary outcomePreventable deathsOpioid overdosesOpioidsAddiction servicesBenzodiazepinesMental healthStudy periodDeathMedical examinersConcordanceStatewide analysisSubstantial numberReceiptDaysDepartmentMedicationsToxicologyFentanylPrescribing
2019
Association of Prescribed Opioids With Increased Risk of Community-Acquired Pneumonia Among Patients With and Without HIV
Edelman EJ, Gordon KS, Crothers K, Akgün K, Bryant KJ, Becker WC, Gaither JR, Gibert CL, Gordon AJ, Marshall BDL, Rodriguez-Barradas MC, Samet JH, Justice AC, Tate JP, Fiellin DA. Association of Prescribed Opioids With Increased Risk of Community-Acquired Pneumonia Among Patients With and Without HIV. JAMA Internal Medicine 2019, 179: 297-304. PMID: 30615036, PMCID: PMC6439696, DOI: 10.1001/jamainternmed.2018.6101.Peer-Reviewed Original ResearchConceptsVeterans Aging Cohort StudyCommunity-acquired pneumoniaImmunosuppressive propertiesPrescribed opioidsCaP riskHIV statusMedian morphine equivalent daily doseVeterans Health Administration medical centersMorphine equivalent daily doseEquivalent daily doseAging Cohort StudyCase-control studyImmune-related outcomesRace/ethnicityIndex dateOpioid exposureCohort studyDaily doseOpioid propertiesStratified analysisMedical CenterMAIN OUTCOMEOpioidsMedicaid dataHIV
2017
Prescribing opioids safely in the emergency department study: Predictors of emergency department discharge with high morphine milligram equivalent prescription
Hawk K, Weiner S, Dziura J, Fiellin D, DaEun D, Nelson L, Hoppe J, Perrone J, D’Onofrio G. Prescribing opioids safely in the emergency department study: Predictors of emergency department discharge with high morphine milligram equivalent prescription. Drug And Alcohol Dependence 2017, 171: e86. DOI: 10.1016/j.drugalcdep.2016.08.242.Peer-Reviewed Original Research
2016
The impact of prescribed opioids on CD4 cell count recovery among HIV‐infected patients newly initiating antiretroviral therapy
Edelman E, Gordon K, Tate J, Becker W, Bryant K, Crothers K, Gaither, Gibert C, Gordon A, Marshall B, Rodriguez‐Barradas M, Samet J, Skanderson M, Justice A, Fiellin D. The impact of prescribed opioids on CD4 cell count recovery among HIV‐infected patients newly initiating antiretroviral therapy. HIV Medicine 2016, 17: 728-739. PMID: 27186715, PMCID: PMC5053822, DOI: 10.1111/hiv.12377.Peer-Reviewed Original ResearchConceptsCD4 cell countBaseline CD4 cell countCell countPrescribed opioidsImmunosuppressive propertiesVeterans Aging Cohort Study (VACS) dataCD4 cell count recoveryAntiretroviral therapy responseCell count recoveryShort-term opioidsViral load suppressionCohort study dataOverall disease severityYear of initiationPrimary independent variableOpioid durationAntiretroviral therapyCount recoveryComorbid conditionsPharmacy dataOpioid propertiesTherapy responseOpioidsPatientsHIV
2015
Incident non-medical use of prescription opioids is associated with heroin initiation among U.S. veterans: A prospective cohort study
Banerjee G, Edelman E, Barry D, Becker W, Cerda M, Crystal S, Gaither J, Gordon A, Gordon K, Kerns R, Martins S, Fiellin D, Marshall B. Incident non-medical use of prescription opioids is associated with heroin initiation among U.S. veterans: A prospective cohort study. Drug And Alcohol Dependence 2015, 156: e14-e15. DOI: 10.1016/j.drugalcdep.2015.07.958.Peer-Reviewed Original Research
2013
Treating Pain in Patients Receiving Methadone Maintenance for Opioid Dependence
Alford D, Barry D, Fiellin D. Treating Pain in Patients Receiving Methadone Maintenance for Opioid Dependence. 2013, 31-37. DOI: 10.1007/978-1-4614-6974-2_3.ChaptersPain complaintsOpioid dependenceMethadone maintenanceChronic painOpioid-dependent patientsIllicit opioid useTreatment of painOpioid usePrescription opioidsMaintenance treatmentPain perceptionClinical challengePainPsychiatric disordersPatientsMethadonePhysiologic toleranceEffective coping skillsComplaintsOpioidsMedicationsTreatmentCoping skillsLoss of controlAddiction
2012
Previous Use of Alcohol, Cigarettes, and Marijuana and Subsequent Abuse of Prescription Opioids in Young Adults
Fiellin LE, Tetrault JM, Becker WC, Fiellin DA, Hoff RA. Previous Use of Alcohol, Cigarettes, and Marijuana and Subsequent Abuse of Prescription Opioids in Young Adults. Journal Of Adolescent Health 2012, 52: 158-163. PMID: 23332479, PMCID: PMC3552239, DOI: 10.1016/j.jadohealth.2012.06.010.Peer-Reviewed Original ResearchConceptsPrescription opioidsPrevious marijuana usePrevious substance usePrevious alcoholMarijuana useSubsequent abuseYoung womenSubstance useYoung adulthoodCommunity-dwelling individualsLogistic regression analysisCurrent abusePrevious alcohol useClinical dataOpioidsDrug useSubstance abuseAlcohol useCigarettesPrevention effortsPrevious useYoung adultsYoung individualsYoung menYear olds
2010
Substance Use in Patients with Sexually Transmitted Infections: Results from a National U.S. Survey
Tetrault JM, Fiellin DA, Niccolai LM, Sullivan LE. Substance Use in Patients with Sexually Transmitted Infections: Results from a National U.S. Survey. American Journal On Addictions 2010, 19: 504-509. PMID: 20958845, DOI: 10.1111/j.1521-0391.2010.00087.x.Peer-Reviewed Original ResearchConceptsAlcohol abuse/dependenceAbuse/dependenceSubstance usePast-year alcohol useMarijuana usePast-month bingeTransmitted InfectionsPrescription opioidsGeneral populationCocaine useNonmedical useAlcohol useHeavy drinkingSTIsNational U.S. SurveyPatientsInfectionOpioidsCliniciansPrevalenceBingeDiagnosisU.S. survey
2008
Narrative review: buprenorphine for opioid-dependent patients in office practice.
Sullivan LE, Fiellin DA. Narrative review: buprenorphine for opioid-dependent patients in office practice. Annals Of Internal Medicine 2008, 148: 662-70. PMID: 18458279, PMCID: PMC3694223, DOI: 10.7326/0003-4819-148-9-200805060-00006.Peer-Reviewed Original ResearchConceptsOpioid dependencePrescription opioidsPartial opioid agonistOpioid-dependent patientsOpioid-dependent personsUse of buprenorphineOffice-based treatmentBuprenorphine-naloxone combinationClinical presentationIllicit opioidsOpioid agonistsPatient populationOpioidsBuprenorphineOffice practicePatientsTreatmentRecent dataPhysiciansAbuseAgonistsPrevalenceHeroin
2007
Non-medical use, abuse and dependence on prescription opioids among U.S. adults: Psychiatric, medical and substance use correlates
Becker WC, Sullivan LE, Tetrault JM, Desai RA, Fiellin DA. Non-medical use, abuse and dependence on prescription opioids among U.S. adults: Psychiatric, medical and substance use correlates. Drug And Alcohol Dependence 2007, 94: 38-47. PMID: 18063321, DOI: 10.1016/j.drugalcdep.2007.09.018.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgoraphobiaAlcohol DrinkingChildChronic DiseaseCross-Sectional StudiesDiagnostic and Statistical Manual of Mental DisordersDrug PrescriptionsFactor Analysis, StatisticalFemaleHealth StatusHumansMaleOpioid-Related DisordersPainPanic DisorderPhobic DisordersPrevalenceSurveys and QuestionnairesUnited StatesConceptsAbuse/dependenceNon-medical usePast-year non-medical usePrescription opioidsLower self-rated health statusNon-medical prescription opioid useAgoraphobic symptomsSelf-rated health statusPrescription opioid useSubstance use correlatesCross-sectional surveyRespondents 18 yearsOpioid useMultivariable analysisPrescription medicationsMultivariable associationsOpioidsHealth statusSubstance misuseDrug useMeet criteriaU.S. adultsPoor healthSubstance useUse correlatesGender and non‐medical use of prescription opioids: results from a national US survey*
Tetrault JM, Desai RA, Becker WC, Fiellin DA, Concato J, Sullivan LE. Gender and non‐medical use of prescription opioids: results from a national US survey*. Addiction 2007, 103: 258-268. PMID: 18042194, DOI: 10.1111/j.1360-0443.2007.02056.x.Peer-Reviewed Original ResearchConceptsPast-year non-medical useNon-medical usePrescription opioidsDrug useSedative/tranquilizer useIllicit drug use disordersAlcohol abuse/dependenceDrug use disordersSerious mental illnessAbuse/dependenceIllicit drug useIllicit substance useSelf-reported alcoholGender-specific factorsCigarette smokingPrescription medicationsRisk factorsOpioidsUse disordersTranquilizer useGender-related factorsMental illnessUS residenceGreater riskSubstance use