The protocol of the Application of Economics & Social psychology to improve Opioid Prescribing Safety trial 2 (AESOPS-2): Availability of opioid harm
Kelley M, Persell S, Linder J, Friedberg M, Meeker D, Fox C, Goldstein N, Knight T, Zein D, Sullivan M, Doctor J. The protocol of the Application of Economics & Social psychology to improve Opioid Prescribing Safety trial 2 (AESOPS-2): Availability of opioid harm. Contemporary Clinical Trials 2021, 112: 106650. PMID: 34896295, PMCID: PMC8869359, DOI: 10.1016/j.cct.2021.106650.Peer-Reviewed Original ResearchConceptsProportion of patientsOpioid-related overdosesOpioid prescribingOpioid-related harmsOpioid use disorderTrial 2Mixed effects regression modelsHarmful patient outcomesDaily MMEMorphine equivalentsPatient overdoseUsual careOpioid usePrimary outcomePrescriber awarenessOpioid harmsPrescribing SafetyPrevention recommendationsIntervention groupPatient outcomesOpioid overdosesUse disordersTreat differencesDisease controlAdditional outcomesThe protocol of the Application of Economics & Social psychology to improve Opioid Prescribing Safety Trial 1 (AESOPS-1): Electronic health record nudges
Kelley M, Persell S, Linder J, Friedberg M, Meeker D, Fox C, Goldstein N, Knight T, Zein D, Rowe T, Sullivan M, Doctor J. The protocol of the Application of Economics & Social psychology to improve Opioid Prescribing Safety Trial 1 (AESOPS-1): Electronic health record nudges. Contemporary Clinical Trials 2021, 103: 106329. PMID: 33636344, PMCID: PMC8089040, DOI: 10.1016/j.cct.2021.106329.Peer-Reviewed Original ResearchConceptsEHR-based interventionsElectronic health recordsPrimary careLong-term opioid useHigh-risk prescriptionsProportion of patientsPrimary care clinicsTrial 1Mixed-effects regression modelsPersistence of effectsDaily MMEMorphine equivalentsNoncancer painLack of evidenceOpioid prescribingOpioid useSecondary outcomesDaily dosePrimary outcomeCare clinicsIntervention armPrescribing SafetyClinical guidelinesControl armIntervention period