2024
Manifestations of human atherosclerosis across vascular beds
Jovin D, Sumpio B, Greif D. Manifestations of human atherosclerosis across vascular beds. JVS-Vascular Insights 2024, 2: 100089. DOI: 10.1016/j.jvsvi.2024.100089.Peer-Reviewed Original ResearchVascular bedClinical managementCarotid arteryCommon risk factorsPeripheral arterial diseaseManagement of carotidClinical management of atherosclerosisEtiology of mortalityIntervention outcomesModel of atherogenesisPathology of atherosclerotic lesionsMedical therapyMeta-analysesTreatment responseFibrotic componentManagement of atherosclerosisLower extremitiesMale sexClinical studiesArtery diseaseMetabolic factorsPeripheral atherosclerosisRisk factorsIndividual patientsVascular territories
2010
Targeting Robo4-Dependent Slit Signaling to Survive the Cytokine Storm in Sepsis and Influenza
London NR, Zhu W, Bozza FA, Smith MC, Greif DM, Sorensen LK, Chen L, Kaminoh Y, Chan AC, Passi SF, Day CW, Barnard DL, Zimmerman GA, Krasnow MA, Li DY. Targeting Robo4-Dependent Slit Signaling to Survive the Cytokine Storm in Sepsis and Influenza. Science Translational Medicine 2010, 2: 23ra19. PMID: 20375003, PMCID: PMC2875996, DOI: 10.1126/scitranslmed.3000678.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCadherinsCapillary PermeabilityCateninsCell LineCytokinesDelta CateninDisease Models, AnimalEndothelium, VascularHumansInfluenza A Virus, H5N1 SubtypeIntercellular Signaling Peptides and ProteinsLipopolysaccharidesMiceMice, Inbred C57BLNerve Tissue ProteinsOrthomyxoviridae InfectionsProtein BindingProtein StabilityProtein TransportReceptors, Cell SurfaceReceptors, ImmunologicSepsisSignal TransductionConceptsInnate immune responseImmune systemCytokine stormImmune responseInfectious agentsHost innate immune responseCurrent medical therapyMultiple inflammatory cytokinesBacterial endotoxin exposureHost immune systemInnate immune systemMultiple infectious agentsAdditional immune responsesPolymicrobial sepsisMedical therapyOrgan failureInflammatory cytokinesCytokine releaseTumor necrosisEndotoxin exposureTissue edemaInterleukin-1betaVascular permeabilityTherapeutic strategiesAnimal models