Netrin instructs synaptic vesicle clustering through Rac GTPase, MIG-10, and the actin cytoskeleton
Stavoe AK, Colón-Ramos DA. Netrin instructs synaptic vesicle clustering through Rac GTPase, MIG-10, and the actin cytoskeleton. Journal Of Cell Biology 2012, 197: 75-88. PMID: 22451697, PMCID: PMC3317799, DOI: 10.1083/jcb.201110127.Peer-Reviewed Original ResearchMeSH KeywordsActin CytoskeletonAnimalsCaenorhabditis elegansCaenorhabditis elegans ProteinsNerve Tissue ProteinsNetrinsRac GTP-Binding ProteinsSynaptic VesiclesConceptsActive zone proteinsActin cytoskeletonUNC-40Synaptic vesiclesSynapse assemblyVesicle clusteringCED-10/Rac1CED-5/DOCK180Receptor UNC-40/DCCPresynaptic regionUNC-40/DCCNetrin receptor UNC-40/DCCZone proteinSynaptic vesicle clusteringSeparate pathways downstreamRole of netrinsCED-5MIG-10Subcellular localizationRac GTPasePathways downstreamCytoskeletonCell migrationNetrinVesicles