2013
Synapse Location during Growth Depends on Glia Location
Shao Z, Watanabe S, Christensen R, Jorgensen EM, Colón-Ramos DA. Synapse Location during Growth Depends on Glia Location. Cell 2013, 154: 337-350. PMID: 23870123, PMCID: PMC3808971, DOI: 10.1016/j.cell.2013.06.028.Peer-Reviewed Original Research
2011
A conserved PTEN/FOXO pathway regulates neuronal morphology during C. elegans development
Christensen R, de la Torre-Ubieta L, Bonni A, Colón-Ramos DA. A conserved PTEN/FOXO pathway regulates neuronal morphology during C. elegans development. Development 2011, 138: 5257-5267. PMID: 22069193, PMCID: PMC3210501, DOI: 10.1242/dev.069062.Peer-Reviewed Original ResearchMeSH KeywordsAnalysis of VarianceAnimalsAnimals, Genetically ModifiedCaenorhabditis elegansCaenorhabditis elegans ProteinsForkhead Transcription FactorsImmunohistochemistryMicroscopy, FluorescenceNeuritesNeurogenesisPhosphatidylinositol 3-KinaseProtein IsoformsRNA InterferenceRNA, Small InterferingSignal TransductionTranscription FactorsTransgenesConceptsDAF-16/FOXOPI3KDAF-18/PTENC. elegans developmentSignal transduction cascadeNeurite outgrowthMajor negative regulatorPI3K pathway activityDaf-18Caenorhabditis elegansDAF-16Transduction cascadeFOXO pathwayNegative regulatorNeuronal cell morphologyNovel roleFOXOMammalian neuronsCorrect developmentPathway activityF isoformsNovel mechanismCell morphologyPathwayNeuronal morphology